CosIng Checker
CosIng Checker
EU cosmetic ingredients, restrictions and safety
Login
RestrictedBinding ruleKRNo English translationOfficial-source import checked

치오글라이콜릭애씨드,그 염류 및 에스텔류

Listed by the Korean MFDS as a cosmetic ingredient requiring conditions of use.

All South Korea recordsOpen ingredient profileCompare all marketsOpen official source

Regulatory decision and full conditions

Status
Restricted
Legal role
Binding rule
Regulatory summary
Listed by the Korean MFDS as a cosmetic ingredient requiring conditions of use.
Conditions and restrictions
?퍼머넌트웨 이브용 및 헤어스트레 이트너 제품에 치오글라이 콜릭애씨드 로서 11% (다만, 가온2욕식 헤어스트레 이트너 제품의 경우에는 치오글라이콜 릭애씨드로서 5%, 치오글라이 콜릭애씨드 및 그 염류를 주성분으로 하고 제1제 사용 시 조제하는 발열 2욕식 퍼머넌트웨이 브용 제품의 경우 치오글라이 콜릭애씨드 로서 19%에 해당하는 양) ?제모용 제품에 치오글라이 콜릭애씨드 로서 5% ?염모제에 치오글라이 콜릭애씨드 로서 1% ?사용 후 씻어내는 두발용 제품류에 2% · 기타 제품에는 사용금지 · 치오글라이콜릭애씨드암모늄티오글라이콜레이트에탄올아민티오글라이콜레이트칼슘티오글라이콜레이트소듐티오글라이콜레이트포타슘티오글라이콜레이트스트론튬티오글라이콜레이트칼슘티오글라이콜레이트하이드록사이드마그네슘티오글라이콜레이트시스테아민티오글라이콜레이트

Substance identity

Official source name
치오글라이콜릭애씨드,그 염류 및 에스텔류
CAS
68-11-1; 5421-46-5; 126-97-6; 814-71-1; 367-51-1; 34452-51-2; 38337-95-0; 65208-41-5; 29820-13-1; 63592-16-5; 2368928-49-6
EC
200-677-4
Identity mapping
cas_number
Linked ingredient
THIOGLYCOLIC ACID
Search this identity across the siteCAS 68-11-1CAS 5421-46-5CAS 126-97-6CAS 814-71-1CAS 367-51-1CAS 34452-51-2CAS 38337-95-0CAS 65208-41-5CAS 29820-13-1CAS 63592-16-5CAS 2368928-49-6EC 200-677-4

Linked CosIng identity data

Names and aliases

THIOGLYCOLIC ACID

CosIng description: Mercaptoacetic acid

EU inventory restriction note: III/2a

Recorded cosmetic function: ANTIOXIDANT, DEPILATORY, HAIR WAVING OR STRAIGHTENING, REDUCING

Function pages:ANTIOXIDANT, DEPILATORY, HAIR WAVING OR STRAIGHTENING, REDUCING

View the complete ingredient profile

Cross-market snapshot for this identity

Exact linked records currently present in this site. An absent market means no imported exact match, not permission to use the substance.

8 market datasets
PubChem 2D chemical structure for CAS 126-97-6
CAS 126-97-6PubChem CID 160430

Verified chemistry for CAS 126-97-6

Monoethanolamine thioglycolate

IUPAC name
2-aminoethanol;2-sulfanylacetic acid
Molecular formula
C4H11NO3S
Molecular weight
153.20 g/mol
Exact mass
153.04596439 Da
Monoisotopic mass
153.04596439 Da
Topological polar surface area
84.6 Ų
Molecular complexity
52.0
Formal charge
0
Hydrogen-bond donors
4
Hydrogen-bond acceptors
5
Rotatable bonds
2
Heavy atoms
9
Covalent units
2

Names and synonyms reported to PubChem

Ethanolamine thioglycolate(2-Hydroxyethyl)ammonium mercaptoacetateEINECS 204-815-4EC 204-815-4263SH5220TTHIOGLYCOLIC ACID MONOETHANOLAMINE SALTN-(2-HYDROXYETHYL)AMMONIUM THIOGLYCOLATEETHANOL, 2-AMINO-, MERCAPTOACETATE (SALT)
10 more reported names
RefChem:819297ETHANOLAMINE THIOGLYCOLATE [INCI]UNII-263SH5220TEthanolamine thioglycolate (ca. 85% in water)2-aminoethanol,2-sulfanylacetic acidEthanolamine MercaptoacetateXTJCJAPNPGGFED-UHFFFAOYSA-NAS-75819Sulfanylacetic acid--2-aminoethan-1-ol (1/1)Ethanolamine thioglycolate (~85% in water), AldrichCPR
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D conformers
0
Machine-readable structure identifiers
SMILES
C(CO)N.C(C(=O)O)S
InChI
InChI=1S/C2H7NO.C2H4O2S/c3-1-2-4;3-2(4)1-5/h4H,1-3H2;5H,1H2,(H,3,4)
InChIKey
XTJCJAPNPGGFED-UHFFFAOYSA-N

Evidence from additional scientific databases

NIH PubChem PUG-View
Exact identifier match160430

Attributed physical-property, hazard, environmental and use annotations.

  • Signal: Danger Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H290 (39.1%): May be corrosive to metals [Warning Corrosive to Metals]; H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]; H315 (60.9%): Causes skin irritation [Warning Skin corrosion/irritation]; H317 (39.1%): May cause an allergic skin reaction [Warning Sensitization, Skin]; H319 (60.9%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P234, P261, P264, P264+P265, P270, P272, P280, P301+P316, P302+P352, P305+P351+P338, P321, P330, P332+P317, P333+P317, P337+P317, P362+P364, P390, P405, P406, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 64 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • Signal: Danger Source: Hazardous Chemical Information System (HCIS), Safe Work Australia
  • GHS Hazard Statements: H301: Toxic if swallowed [Danger Acute toxicity, oral]; H312: Harmful in contact with skin [Warning Acute toxicity, dermal]; H315: Causes skin irritation [Warning Skin corrosion/irritation]; H317: May cause an allergic skin reaction [Warning Sensitization, Skin]; H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H330: Fatal if inhaled [Danger Acute toxicity, inhalation]; H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]; H373: May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure] Source: Hazardous Chemical Information System (HCIS), Safe Work Australia
  • Precautionary Statement Codes: P260, P261, P264, P264+P265, P270, P271, P272, P280, P284, P301+P316, P302+P352, P304+P340, P305+P351+P338, P316, P317, P319, P320, P321, P330, P332+P317, P333+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement) Source: Hazardous Chemical Information System (HCIS), Safe Work Australia
  • Cosmetic Ingredient Review Conclusion: Based on the available data, the CIR Expert Panel concluded that ... Ethanolamine Thioglycolate is safe for use in hair straighteners, permanent waves, tonics, dressings, and so forth, wave sets, other non-coloring hair products, and hair dyes and colors, as described in this safety assessment, at concentrations up to 15.2% (as Thioglycolic Acid). Hairdressers should avoid skin contact and minimize consumer skin exposure. Source: Cosmetic Ingredient Review (CIR)
  • Cosmetic Ingredient Review Finding(s): Safe for use in cosmetics, with qualifications Source: Cosmetic Ingredient Review (CIR)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 29820-13-1
CAS 29820-13-1PubChem CID 22039

Verified chemistry for CAS 29820-13-1

(2-(Mercapto-kappaS)acetato(2-)-kappaO)calcium

IUPAC name
calcium 2-sulfidoacetate
Molecular formula
C2H2CaO2S
Molecular weight
130.18 g/mol
Exact mass
129.9401413 Da
Monoisotopic mass
129.9401413 Da
Topological polar surface area
41.1 Ų
Molecular complexity
37.0
Formal charge
0
Hydrogen-bond donors
0
Hydrogen-bond acceptors
3
Rotatable bonds
0
Heavy atoms
6
Covalent units
2

Names and synonyms reported to PubChem

Calcium, (mercaptoacetato(2-)-O,S)-Calcium, [mercaptoacetato(2-)-O,S]-(Mercaptoacetato(2-)-O,S)calciumMercaptoacetic acid, monocalcium saltCalcium, (2-(mercapto-kappaS)acetato(2-)-kappaO)-RefChem:395121253-511-8Calcium thioglycolate (1:1)
12 more reported names
Calcium sulphidoacetatecalcium;2-sulfidoacetateAcetic acid, mercapto-, calcium salt (1:1)Thioglycolic acid calcium saltAcetic acid, 2-mercapto-, calcium salt (1:1)EINECS 249-881-5calcium sulfidoacetateC2H2CaO2SEC 249-881-5Mercaptoacetic Acid Calcium SaltQVCFQEFEMBCIOI-UHFFFAOYSA-LDB-369920
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D conformers
0
Machine-readable structure identifiers
SMILES
C(C(=O)[O-])[S-].[Ca+2]
InChI
InChI=1S/C2H4O2S.Ca/c3-2(4)1-5;/h5H,1H2,(H,3,4);/q;+2/p-2
InChIKey
QVCFQEFEMBCIOI-UHFFFAOYSA-L

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 34452-51-2
CAS 34452-51-2PubChem CID 23688957

Verified chemistry for CAS 34452-51-2

Potassium Thioglycolate

IUPAC name
potassium 2-sulfanylacetate
Molecular formula
C2H3KO2S
Molecular weight
130.21 g/mol
Exact mass
129.94908199 Da
Monoisotopic mass
129.94908199 Da
Topological polar surface area
41.1 Ų
Molecular complexity
46.0
Formal charge
0
Hydrogen-bond donors
1
Hydrogen-bond acceptors
3
Rotatable bonds
1
Heavy atoms
6
Covalent units
2

Names and synonyms reported to PubChem

Potassium 2-mercaptoacetateAcetic acid, mercapto-, monopotassium saltUNII-XP5WZO5W6HXP5WZO5W6HEINECS 252-038-4Acetic acid, 2-mercapto-, potassium salt (1:1)EC 252-038-4Mercaptoacetic acid, monopotassium salt
12 more reported names
RefChem:175626POTASSIUM THIOGLYCOLATE [INCI]252-038-4potassium;2-sulfanylacetatePotassium mercaptoacetatepotassium sulfanylacetatepotassium,2-sulfanylacetatePotassium2-mercaptoacetateC2H3KO2SHYTYHTSMCRDHIM-UHFFFAOYSA-MDB-371697Mercaptoacetic acid potassium, 40 to 44% aqueous solution
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D conformers
0
Machine-readable structure identifiers
SMILES
C(C(=O)[O-])S.[K+]
InChI
InChI=1S/C2H4O2S.K/c3-2(4)1-5;/h5H,1H2,(H,3,4);/q;+1/p-1
InChIKey
HYTYHTSMCRDHIM-UHFFFAOYSA-M

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 367-51-1
CAS 367-51-1PubChem CID 23690444

Verified chemistry for CAS 367-51-1

Sodium Thioglycolate

IUPAC name
sodium 2-sulfanylacetate
Molecular formula
C2H3NaO2S
Molecular weight
114.10 g/mol
Exact mass
113.97514479 Da
Monoisotopic mass
113.97514479 Da
Topological polar surface area
41.1 Ų
Molecular complexity
46.0
Formal charge
0
Hydrogen-bond donors
1
Hydrogen-bond acceptors
3
Rotatable bonds
1
Heavy atoms
6
Covalent units
2

Names and synonyms reported to PubChem

Sodium mercaptoacetateMercaptoacetic acid sodium saltThioglycolate sodiumSodium thioglycollateMercaptoacetic acid, sodium saltsodium sulfanylacetateSodium 2-mercatoethanoateThioglycollic acid, sodium salt
16 more reported names
Acetic acid, mercapto-, monosodium saltThioglycolic acid, sodium saltCCRIS 4874USAF EK-5199EINECS 206-696-4EINECS 253-166-3Thioglycolic acid sodium saltUNII-D94M78P69VCHEBI:86481SODIUM THIOGLYCOLATE [II]SODIUM THIOGLYCOLATE [MI]EC 206-696-4SODIUM THIOGLYCOLATE (II)Sodium 2sulfanylacetateSodium 2mercatoethanoateTHIOGLYCOLATESODIUM
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D conformers
0
Machine-readable structure identifiers
SMILES
C(C(=O)[O-])S.[Na+]
InChI
InChI=1S/C2H4O2S.Na/c3-2(4)1-5;/h5H,1H2,(H,3,4);/q;+1/p-1
InChIKey
GNBVPFITFYNRCN-UHFFFAOYSA-M

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 38337-95-0
CAS 38337-95-0PubChem CID 3084699

Verified chemistry for CAS 38337-95-0

mercaptoacetic acid, strontium salt

IUPAC name
strontium 2-sulfanylacetic acid
Molecular formula
C2H4O2SSr+2
Formula without charge
C2H4O2SSr
Molecular weight
179.74 g/mol
Exact mass
179.89881279 Da
Monoisotopic mass
179.89881279 Da
Topological polar surface area
38.3 Ų
Molecular complexity
42.0
Formal charge
2
Hydrogen-bond donors
2
Hydrogen-bond acceptors
3
Rotatable bonds
1
Heavy atoms
6
Covalent units
2

Names and synonyms reported to PubChem

EINECS 253-888-9RefChem:156554YDYVEEZRHSAYMD-UHFFFAOYSA-N
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D conformers
0
Machine-readable structure identifiers
SMILES
C(C(=O)O)S.[Sr+2]
InChI
InChI=1S/C2H4O2S.Sr/c3-2(4)1-5;/h5H,1H2,(H,3,4);/q;+2
InChIKey
YDYVEEZRHSAYMD-UHFFFAOYSA-N

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 5421-46-5
CAS 5421-46-5PubChem CID 21534

Verified chemistry for CAS 5421-46-5

Ammonium Thioglycolate

Ammonium thioglycolate is an organic ammonium salt having thioglycolate(1) as the counterion. Also known as perm salt, it has use in perming hair. It has a role as an allergen and a reducing agent. It contains a thioglycolate(1-). — ChEBI

IUPAC name
azanium 2-sulfanylacetate
Molecular formula
C2H7NO2S
Molecular weight
109.15 g/mol
Exact mass
109.01974964 Da
Monoisotopic mass
109.01974964 Da
Topological polar surface area
42.1 Ų
Molecular complexity
37.0
Formal charge
0
Hydrogen-bond donors
2
Hydrogen-bond acceptors
3
Rotatable bonds
0
Heavy atoms
6
Covalent units
2

Names and synonyms reported to PubChem

Ammonium mercaptoacetateThioglycolic acid ammonium saltThiofaco A-50Acetic acid, mercapto-, monoammonium saltAmmonium thioglycollateUSAF MO-2ammonium sulfanylacetateHSDB 7167
16 more reported names
Thioglycollic acid, ammonium saltNSC 6954UNII-6P9E788VZZEINECS 226-540-9Mercaptoacetic acid, monoammonium salt6P9E788VZZAI3-26246Acetic acid, 2-mercapto-, ammonium salt (1:1)CHEBI:156555EC 226-540-9NSC-6954AMMONIUM THIOGLYCOLATE [HSDB]Thiofaco A50Ammonium thiogylcollateRefChem:112211Thiogylcollic acid, ammonium salt
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D conformers
0
Machine-readable structure identifiers
SMILES
C(C(=O)[O-])S.[NH4+]
InChI
InChI=1S/C2H4O2S.H3N/c3-2(4)1-5;/h5H,1H2,(H,3,4);1H3
InChIKey
ZZTCCAPMZLDHFM-UHFFFAOYSA-N

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 63592-16-5
CAS 63592-16-5PubChem CID 22027387

Verified chemistry for CAS 63592-16-5

Magnesium Thioglycolate

IUPAC name
magnesium bis(2-sulfanylacetate)
Molecular formula
C4H6MgO4S2
Molecular weight
206.5 g/mol
Exact mass
205.9557927 Da
Monoisotopic mass
205.9557927 Da
Topological polar surface area
82.3 Ų
Molecular complexity
37.0
Formal charge
0
Hydrogen-bond donors
2
Hydrogen-bond acceptors
6
Rotatable bonds
0
Heavy atoms
11
Covalent units
3

Names and synonyms reported to PubChem

UNII-8E96N0WA3XEINECS 264-358-18E96N0WA3XMAGNESIUM, BIS(MERCAPTOACETATO-O,S)-, (T-4)-MAGNESIUM, BIS((MERCAPTO-.KAPPA.S)ACETATO-.KAPPA.O)-, (T-4)-MAGNESIUM, BIS(2-(MERCAPTO-.KAPPA.S)ACETATO-.KAPPA.O)-, (T-4)-RefChem:155278MAGNESIUM THIOGLYCOLATE [INCI]
6 more reported names
MAGNESIUM, BIS((MERCAPTO-KAPPAS)ACETATO-KAPPAO)-, (T-4)-MAGNESIUM, BIS(2-(MERCAPTO-KAPPAS)ACETATO-KAPPAO)-, (T-4)-264-358-1Bis(mercaptoacetato-O,S)magnesiumMagnesium 2-mercaptoacetateMagnesium bis(sulfanylacetate)
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D conformers
0
Machine-readable structure identifiers
SMILES
C(C(=O)[O-])S.C(C(=O)[O-])S.[Mg+2]
InChI
InChI=1S/2C2H4O2S.Mg/c2*3-2(4)1-5;/h2*5H,1H2,(H,3,4);/q;;+2/p-2
InChIKey
ZHALCRSGRSWRHV-UHFFFAOYSA-L

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 65208-41-5
CAS 65208-41-5PubChem CID 56840831

Verified chemistry for CAS 65208-41-5

Calcium sulfidoacetate--water (1/1/3)

IUPAC name
calcium;2-sulfidoacetate;trihydrate
Molecular formula
C2H8CaO5S
Molecular weight
184.23 g/mol
Exact mass
183.9718354 Da
Monoisotopic mass
183.9718354 Da
Topological polar surface area
44.1 Ų
Molecular complexity
37.0
Formal charge
0
Hydrogen-bond donors
3
Hydrogen-bond acceptors
6
Rotatable bonds
0
Heavy atoms
9
Covalent units
5

Names and synonyms reported to PubChem

RefChem:331596C2H8CaO5SUM6R6Q3WPX
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D conformers
0
Machine-readable structure identifiers
SMILES
C(C(=O)[O-])[S-].O.O.O.[Ca+2]
InChI
InChI=1S/C2H4O2S.Ca.3H2O/c3-2(4)1-5;;;;/h5H,1H2,(H,3,4);;3*1H2/q;+2;;;/p-2
InChIKey
LXFGCHNAIROWHI-UHFFFAOYSA-L

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 68-11-1
CAS 68-11-1PubChem CID 1133

Verified chemistry for CAS 68-11-1

Thioglycolic Acid

Thioglycolic acid is a sulfur-containing carboxylic acid. It is a conjugate acid of a thioglycolate(1-). — ChEBI

IUPAC name
2-sulfanylacetic acid
Molecular formula
C2H4O2S
Molecular weight
92.12 g/mol
Exact mass
91.99320054 Da
Monoisotopic mass
91.99320054 Da
XLogP3
0.1
Topological polar surface area
38.3 Ų
Molecular complexity
42.0
Formal charge
0
Hydrogen-bond donors
2
Hydrogen-bond acceptors
3
Rotatable bonds
1
Heavy atoms
5
Covalent units
1

Names and synonyms reported to PubChem

mercaptoacetic acid2-Mercaptoacetic acid2-Thioglycolic acidThioglycollic acidAcetic acid, mercapto-Sulfanylacetic acidThiovanic acidMercaptoessigsaeure
16 more reported names
Glycolic acid, thio-USAF CB-35Acide thioglycoliqueGlycolic acid, 2-thio-Mercaptoethanoic acidKyselina thioglykolovaKyselina merkaptooctovaalpha-Mercaptoacetic acidNSC-18947857H94KHMCHEBI:300652-mercaptoethanoic acidRefChem:897804200-677-4Acetic acid, 2-mercapto-mercapto acetic acid
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D pharmacophore features
3
3D rings
0
3D hydrophobes
0
3D acceptor features
2
3D donor features
0
3D anionic centres
1
3D cationic centres
0
3D conformers
2
Effective 3D rotors
1.0
Machine-readable structure identifiers
SMILES
C(C(=O)O)S
InChI
InChI=1S/C2H4O2S/c3-2(4)1-5/h5H,1H2,(H,3,4)
InChIKey
CWERGRDVMFNCDR-UHFFFAOYSA-N

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 814-71-1
CAS 814-71-1PubChem CID 13141

Verified chemistry for CAS 814-71-1

Calcium Thioglycolate

IUPAC name
calcium bis(2-sulfanylacetate)
Molecular formula
C4H6CaO4S2
Molecular weight
222.3 g/mol
Exact mass
221.9333419 Da
Monoisotopic mass
221.9333419 Da
Topological polar surface area
82.3 Ų
Molecular complexity
37.0
Formal charge
0
Hydrogen-bond donors
2
Hydrogen-bond acceptors
6
Rotatable bonds
0
Heavy atoms
11
Covalent units
3

Names and synonyms reported to PubChem

Acetic acid, mercapto-, calcium salt (2:1)EbacreamDepilCalcium thioglycollateCalcium mercaptoacetateJullyVikorCalcium bis(mercaptoacetate)
16 more reported names
Acetic acid, 2-mercapto-, calcium salt (2:1)Mercaptoacetic acid calcium derivativeRefChem:122917Secret Dig Hair Removal FoamSecret Dig hair removal spray foamSecret Dig Hair Removal Foam SpraySecret Dig hair removal spray. foam212-402-5249-881-5SurgexCalcium 2-mercaptoacetatecalcium;2-sulfanylacetateUNII-J96129652NEINECS 212-402-5HSDB 1962calcium bis(sulfanylacetate)
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D conformers
0
Machine-readable structure identifiers
SMILES
C(C(=O)[O-])S.C(C(=O)[O-])S.[Ca+2]
InChI
InChI=1S/2C2H4O2S.Ca/c2*3-2(4)1-5;/h2*5H,1H2,(H,3,4);/q;;+2/p-2
InChIKey
CNYFJCCVJNARLE-UHFFFAOYSA-L

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Official source and provenance

Registered source
South Korea MFDS cosmetic ingredient data
Source reference
화장품 안전기준 등에 관한 규정, 별표 2, record 2-390
Source record ID
2-390
Source version
2026-19
Source language
Korean
Translation status
No English translation
Effective date
2026-03-18
Source updated
2026-03-18
Snapshot checked
2026-08-30 04:33 UTC
Validation method
MFDS JSON appendices 1–2 parse; 1077 prohibited, 243 restricted
SHA-256
056de35b843a5e31f709073f9e79d5e6e18f7c9164eb537bb099b185a37ef7d8

Registered dataset notes

Dataset coverage
Ingredient identity and separate restriction/regulation data endpoints
Authority note
Korean source is canonical; English materials alone are not complete enough for certification
Inspect the exact official sourceRegulator guidance

How this record fits the market dataset

1320
current South Korea records
243
records marked Restricted
1320
records from this source version
1252
market records with CAS identity

Status distribution

Prohibited: 1077Restricted: 243

Condition text is present on 638 of 1320 current records. An empty condition field is interpreted according to the record type above; it is never converted into an unrestricted-use claim.

South Korea market context

Complete current appendix dataset

Coverage version: MFDS Notice 2026-19, effective 18 March 2026

All rows in official Appendix 1 (prohibited) and Appendix 2 (restricted) of the Safety Standards for Cosmetics.

Verification checklist

  1. Match the Korean canonical substance name and identifiers.
  2. Review all Appendix 1 and 2 matches and conditions.
  3. Check functional-cosmetic and positive-list requirements where applicable.
  4. Confirm current MFDS notice, responsible seller and label obligations.

Official market sources

Verification workflow and record completeness

Before using this result in a compliance decision

  1. Confirm that “치오글라이콜릭애씨드,그 염류 및 에스텔류” and every CAS/EC identifier refer to the material in your supplier specification.
  2. Match the Korean canonical substance name and identifiers.
  3. Review all Appendix 1 and 2 matches and conditions.
  4. Check functional-cosmetic and positive-list requirements where applicable.
  5. Confirm current MFDS notice, responsible seller and label obligations.
  6. Document the source version and recheck the regulator before manufacture, notification or market placement.

Fields available in this record

  • Official substance nameAvailable
  • CASAvailable
  • ECAvailable
  • Separate condition textAvailable
  • Effective dateAvailable
  • Snapshot hash and methodAvailable

Questions this page answers

This substance is not unrestricted: cosmetic use is subject to the conditions in the cited official record. Check product type, body area, concentration, purity and warning requirements before deciding whether a formulation is compliant.

If this row does not reproduce conditions, open the cited official detail because omission does not mean unrestricted use. Korean source wording is canonical and other positive lists/notices may still apply to the formulation.

The record cites 화장품 안전기준 등에 관한 규정, 별표 2, record 2-390, source version 2026-19. Open the official source.

No. CAS helps resolve identity, but jurisdictions can classify the same substance differently and can apply different product scopes, limits, warnings and transition dates.

Stable citation

치오글라이콜릭애씨드,그 염류 및 에스텔류. 화장품 안전기준 등에 관한 규정, 별표 2, record 2-390. South Korea. Source version 2026-19. CosIng Checker regulatory record: https://cosingchecker.com/regulations/kr/records/2117/

Cite the regulator as the legal authority. This page is a structured evidence index and verification aid, not a substitute for the official text or professional legal assessment.

Interpretation and limits for South Korea

This substance is not unrestricted: cosmetic use is subject to the conditions in the cited official record.

Check product type, body area, concentration, purity and warning requirements before deciding whether a formulation is compliant.

How to interpret the legal role

The cited row forms part of a binding rule or legally incorporated list for this market.

Evidence on this page

  • Recorded outcome: Restricted
  • Legal role: Binding rule
  • Source version: 2026-19
  • Effective date: 2026-03-18

What it does not prove

Korean source wording is canonical and other positive lists/notices may still apply to the formulation.

Further authoritative substance research

These sources can add identity, safety, exposure or hazard context. A link is not evidence that the database contains this exact substance, and none of these sources overrides the market decision above.

Cosmetic Ingredient Review safety assessments

Expert Panel conclusions, assessed ingredient groups, use conditions, dates and report documents

Independent expert review considered by FDA; not a government approval or binding market rule

Research this identity at the source

FDA Global Substance Registration System

UNII identifiers, preferred names, substance types, codes and public substance relationships

Identity registry only; UNII availability does not imply FDA review or approval

Research this identity at the source

ILO/WHO International Chemical Safety Cards

Hazards, symptoms, first aid, storage, incompatibilities and physical properties for covered chemicals

International occupational chemical-safety reference; not cosmetic-use approval

Research this identity at the source

Japan NITE-CHRIP

Chemical identity, Japanese and foreign legal lists, GHS hazards and exposure-related information

Chemical-management evidence; cosmetic status remains governed by the applicable MHLW standard and market rules

Research this identity at the source

NIOSH Pocket Guide to Chemical Hazards

REL, PEL, IDLH, properties, exposure routes, symptoms, target organs, first aid and measurement methods for covered workplace chemicals

US occupational-health guidance and limits; not a cosmetic ingredient decision

Research this identity at the source

OECD eChemPortal

Gateway to authority-owned physical-property, fate, ecotoxicity, toxicity, exposure and GHS records

Discovery gateway; each linked authority remains responsible for its data

Research this identity at the source

US EPA CompTox CTX APIs

API key required for import

DTXSID identity, experimental and predicted properties, toxicity, bioactivity, exposure and environmental data

Scientific and computational evidence; predictions must remain labelled and do not determine cosmetic legality

Research this identity at the source