징크페놀설포네이트
Listed by the Korean MFDS as a cosmetic ingredient requiring conditions of use.
Regulatory decision and full conditions
- Status
- Restricted
- Legal role
- Binding rule
- Regulatory summary
- Listed by the Korean MFDS as a cosmetic ingredient requiring conditions of use.
- Conditions and restrictions
- 사용 후 씻어내지 않는 제품에 2%
Substance identity
- Official source name
- 징크페놀설포네이트
- CAS
- 127-82-2
- EC
- 204-867-8
- Identity mapping
- cas_number
- Linked ingredient
- ZINC PHENOLSULFONATE
Linked CosIng identity data
Names and aliases
CosIng description: Zinc bis(4-hydroxybenzenesulphonate)
EU inventory restriction note: III/25
Recorded cosmetic function: ANTIMICROBIAL, ASTRINGENT, DEODORANT
Function pages:ANTIMICROBIAL, ASTRINGENT, DEODORANT
View the complete ingredient profileCross-market snapshot for this identity
Exact linked records currently present in this site. An absent market means no imported exact match, not permission to use the substance.
European Union
1 linked record · 1 with specific conditions
Open supporting recordGreat Britain
1 linked record · 1 with specific conditions
Open supporting recordNew Zealand
1 linked record · 1 with specific conditions
Open supporting recordSouth Korea
Current record1 linked record · 1 with specific conditions
Open supporting recordIndia
1 linked record · 1 with specific conditions
Open supporting recordSaudi Arabia
1 linked record
Open supporting recordVerified chemistry for CAS 127-82-2
Zinc Phenolsulfonate
- IUPAC name
- zinc bis(4-hydroxybenzenesulfonate)
- Molecular formula
- C12H10O8S2Zn
- Molecular weight
- 411.7 g/mol
- Exact mass
- 409.910851 Da
- Monoisotopic mass
- 409.910851 Da
- Topological polar surface area
- 172.0 Ų
- Molecular complexity
- 194.0
- Formal charge
- 0
- Hydrogen-bond donors
- 2
- Hydrogen-bond acceptors
- 8
- Rotatable bonds
- 0
- Heavy atoms
- 23
- Covalent units
- 3
Names and synonyms reported to PubChem
16 more reported names
External database identifiers
- EPA DTXSID:DTXSID1059571
Advanced structure statistics
- Defined atom stereocentres
- 0
- Undefined atom stereocentres
- 0
- Defined bond stereocentres
- 0
- Undefined bond stereocentres
- 0
- 3D conformers
- 0
Machine-readable structure identifiers
- SMILES
C1=CC(=CC=C1O)S(=O)(=O)[O-].C1=CC(=CC=C1O)S(=O)(=O)[O-].[Zn+2]- InChI
InChI=1S/2C6H6O4S.Zn/c2*7-5-1-3-6(4-2-5)11(8,9)10;/h2*1-4,7H,(H,8,9,10);/q;;+2/p-2- InChIKey
ZNVKGUVDRSSWHV-UHFFFAOYSA-L
Evidence from additional scientific databases
NIH PubChem PUG-View
Attributed physical-property, hazard, environmental and use annotations.
- Boiling Point: 248 °F at 760 mmHg (decomposes) (USCG, 1999) Source: CAMEO Chemicals
- Color/Form: Colorless transparent crystals or white granular powder Source: Hazardous Substances Data Bank (HSDB)
- Density: greater than 1 at 68 °F (USCG, 1999) Source: CAMEO Chemicals
- Odor: Odorless Source: Hazardous Substances Data Bank (HSDB)
- Physical Description: Zinc phenolsulfonate appears as a colorless to white crystalline solid which turns pink on exposure to air. The primary is the threat to the environment. Immediate steps should be taken to limit its spread to the environment. It is soluble in water. It is used as an insecticide and in medicine. Source: CAMEO Chemicals
- Physical Description: Octahydrate: Odorless solid; Effloresces in dry air; [Merck Index] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Solubility: Solubility: 62.5 g/100 cc cold water; 250 g/100 cc water at 100 °C; 55.6 g/100 cc alcohol at 25 °C /Octahydrate/ Source: Hazardous Substances Data Bank (HSDB)
- pH: Moderate acidity Source: Hazardous Substances Data Bank (HSDB)
- Carcinogen Classification: No indication of carcinogenicity to humans (not listed by IARC). Source: Toxin and Toxin Target Database (T3DB)
- Exposure Routes: Oral (L49) ; inhalation (L49) ; dermal (L49) Source: Toxin and Toxin Target Database (T3DB)
- First Aid: INHALATION: move to fresh air.; INGESTION: if large amount has been swallowed, induce vomiting, followed by prompt and complete gastric lavage, cathartics, and demulcents.; EYES or SKIN: flush with water. (USCG, 1999) Source: CAMEO Chemicals
- Note: This chemical does not meet GHS hazard criteria for 46.8% (36 of 77) of reports. Source: European Chemicals Agency (ECHA)
- Signal: Warning Source: European Chemicals Agency (ECHA)
- GHS Hazard Statements: H302 (53.2%): Harmful if swallowed [Warning Acute toxicity, oral]; H315 (51.9%): Causes skin irritation [Warning Skin corrosion/irritation]; H319 (51.9%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H335 (51.9%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation] Source: European Chemicals Agency (ECHA)
- Precautionary Statement Codes: P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
- ECHA C&L Notifications Summary: Aggregated GHS information provided per 77 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Reported as not meeting GHS hazard criteria per 36 of 77 reports by companies.; There are 4 notifications provided by 41 of 77 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
- Health Effects: Chronic exposure to zinc causes anemia, atazia, lethargy, and decreases the level of good cholesterol in the body. It is also believed to cause pancreatic and reproductive damage. (L49) Source: Toxin and Toxin Target Database (T3DB)
- Cosmetic Ingredient Review Finding(s): Safe in the present practices of use and concentration. Ingredient, concentration, and use information are available in documents discoverable at https://cir-reports.cir-safety.org Source: Cosmetic Ingredient Review (CIR)
- Toxicity Summary: Anaemia results from the excessive absorption of zinc suppressing copper and iron absorption, most likely through competitive binding of intestinal mucosal cells. Unbalanced levels of copper and zinc binding to Cu,Zn-superoxide dismutase has been linked to amyotrophic lateral sclerosis (ALS). Stomach acid dissolves metallic zinc to give corrosive zinc chloride, which can cause damage to the stomach lining. Metal fume fever is thought to be an immune response to inhaled zinc. (L48, L49, A49) Source: Toxin and Toxin Target Database (T3DB)
- Cosmetic Ingredient Review Link: CIR ingredient: Zinc Phenolsulfonate Source: Cosmetic Ingredient Review (CIR)
- Sources/Uses: Used in insecticides, topical antiperspirants, mouthwashes, and veterinary wound antiseptics; [HSDB] An astringent; [EPA OHM/TADS] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Industrial Processes with risk of exposure: Using Disinfectants or Biocides [Category: Clean]; Farming (Pesticides) [Category: Industry] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Uses: IN INSECTICIDE FORMULATIONS Source: Hazardous Substances Data Bank (HSDB)
- Uses: MEDICATION Source: Hazardous Substances Data Bank (HSDB)
- Uses: MEDICATION (VET) Source: Hazardous Substances Data Bank (HSDB)
- Uses: COMMONLY USED TOPICALLY AS ANTIPERSPIRANT Source: Hazardous Substances Data Bank (HSDB)
Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record
Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.
Additional source coverage and match status
| Source | Result | Checked |
|---|---|---|
| NIH PubChem PUG-View | Exact match | 2026-08-31 |
A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
Official source and provenance
- Registered source
- South Korea MFDS cosmetic ingredient data
- Source reference
- 화장품 안전기준 등에 관한 규정, 별표 2, record 2-388
- Source record ID
2-388- Source version
- 2026-19
- Source language
- Korean
- Translation status
- No English translation
- Effective date
- 2026-03-18
- Source updated
- 2026-03-18
- Snapshot checked
- 2026-08-30 04:33 UTC
- Validation method
- MFDS JSON appendices 1–2 parse; 1077 prohibited, 243 restricted
- SHA-256
056de35b843a5e31f709073f9e79d5e6e18f7c9164eb537bb099b185a37ef7d8
Registered dataset notes
- Dataset coverage
- Ingredient identity and separate restriction/regulation data endpoints
- Authority note
- Korean source is canonical; English materials alone are not complete enough for certification
How this record fits the market dataset
Status distribution
Condition text is present on 638 of 1320 current records. An empty condition field is interpreted according to the record type above; it is never converted into an unrestricted-use claim.
South Korea market context
Complete current appendix dataset
Coverage version: MFDS Notice 2026-19, effective 18 March 2026
All rows in official Appendix 1 (prohibited) and Appendix 2 (restricted) of the Safety Standards for Cosmetics.
Verification checklist
- Match the Korean canonical substance name and identifiers.
- Review all Appendix 1 and 2 matches and conditions.
- Check functional-cosmetic and positive-list requirements where applicable.
- Confirm current MFDS notice, responsible seller and label obligations.
Official market sources
- South Korea MFDS cosmetic ingredient dataKorean source is canonical; English materials alone are not complete enough for certification
Verification workflow and record completeness
Before using this result in a compliance decision
- Confirm that “징크페놀설포네이트” and every CAS/EC identifier refer to the material in your supplier specification.
- Match the Korean canonical substance name and identifiers.
- Review all Appendix 1 and 2 matches and conditions.
- Check functional-cosmetic and positive-list requirements where applicable.
- Confirm current MFDS notice, responsible seller and label obligations.
- Document the source version and recheck the regulator before manufacture, notification or market placement.
Fields available in this record
- Official substance nameAvailable
- CASAvailable
- ECAvailable
- Separate condition textAvailable
- Effective dateAvailable
- Snapshot hash and methodAvailable
Questions this page answers
Stable citation
징크페놀설포네이트. 화장품 안전기준 등에 관한 규정, 별표 2, record 2-388. South Korea. Source version 2026-19. CosIng Checker regulatory record: https://cosingchecker.com/regulations/kr/records/2116/
Cite the regulator as the legal authority. This page is a structured evidence index and verification aid, not a substitute for the official text or professional legal assessment.
Interpretation and limits for South Korea
This substance is not unrestricted: cosmetic use is subject to the conditions in the cited official record.
Check product type, body area, concentration, purity and warning requirements before deciding whether a formulation is compliant.
How to interpret the legal role
The cited row forms part of a binding rule or legally incorporated list for this market.
Evidence on this page
- Recorded outcome: Restricted
- Legal role: Binding rule
- Source version: 2026-19
- Effective date: 2026-03-18
What it does not prove
Korean source wording is canonical and other positive lists/notices may still apply to the formulation.
Further authoritative substance research
These sources can add identity, safety, exposure or hazard context. A link is not evidence that the database contains this exact substance, and none of these sources overrides the market decision above.
Cosmetic Ingredient Review safety assessments
Expert Panel conclusions, assessed ingredient groups, use conditions, dates and report documents
Independent expert review considered by FDA; not a government approval or binding market rule
Research this identity at the sourceFDA Global Substance Registration System
UNII identifiers, preferred names, substance types, codes and public substance relationships
Identity registry only; UNII availability does not imply FDA review or approval
Research this identity at the sourceILO/WHO International Chemical Safety Cards
Hazards, symptoms, first aid, storage, incompatibilities and physical properties for covered chemicals
International occupational chemical-safety reference; not cosmetic-use approval
Research this identity at the sourceJapan NITE-CHRIP
Chemical identity, Japanese and foreign legal lists, GHS hazards and exposure-related information
Chemical-management evidence; cosmetic status remains governed by the applicable MHLW standard and market rules
Research this identity at the sourceNIOSH Pocket Guide to Chemical Hazards
REL, PEL, IDLH, properties, exposure routes, symptoms, target organs, first aid and measurement methods for covered workplace chemicals
US occupational-health guidance and limits; not a cosmetic ingredient decision
Research this identity at the sourceOECD eChemPortal
Gateway to authority-owned physical-property, fate, ecotoxicity, toxicity, exposure and GHS records
Discovery gateway; each linked authority remains responsible for its data
Research this identity at the sourceUS EPA CompTox CTX APIs
API key required for importDTXSID identity, experimental and predicted properties, toxicity, bioactivity, exposure and environmental data
Scientific and computational evidence; predictions must remain labelled and do not determine cosmetic legality
Research this identity at the source