Why does CAS 68-11-1 appear in more than one EU cosmetic annex?

A substance identified by CAS 68-11-1 may appear in multiple EU cosmetic regulation annexes when it is subject to different conditions in different contexts — for example, restricted under Annex III with specific conditions, while also appearing in Annex IV as an approved colorant under separate entry conditions. Each entry must be reviewed individually.

How do I check if my formula contains a substance with CAS 68-11-1?

Use the INCI Checker on CosIng Checker with INCI names, CAS numbers or EC numbers. Paste CAS 68-11-1 to screen it directly, then review every linked annex record and supplier document.

CAS 1 record

CAS 68-11-1

Q: How do I use CAS 68-11-1 for compliance screening?

Cross-reference CAS 68-11-1 against your raw material specification sheets and CoA documents. When it appears in Annex II, verify absence. When it appears in Annex III, verify that concentration limits and product type conditions are met. All annex entries sharing this CAS number are listed on this page.

CAS 68-11-1 matches 1 EU annex record across Annex II–VI of Regulation 1223/2009.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 68-11-1

CAS 68-11-1PubChem CID 1133

Thioglycolic Acid

Thioglycolic acid is a sulfur-containing carboxylic acid. It is a conjugate acid of a thioglycolate(1-). — ChEBI

IUPAC name: 2-sulfanylacetic acid

Molecular formula: C2H4O2S
Molecular weight: 92.12 g/mol
Exact mass: 91.99320054 Da
XLogP3: 0.1
Topological polar surface area: 38.3 Å²
Hydrogen-bond donors: 2
Hydrogen-bond acceptors: 3
Covalent units: 1
Defined stereocentres: 0

Also known as

mercaptoacetic acid2-Mercaptoacetic acid2-Thioglycolic acidThioglycollic acidAcetic acid, mercapto-Sulfanylacetic acidThiovanic acidMercaptoessigsaeure

16 more reported names

Glycolic acid, thio-USAF CB-35Acide thioglycoliqueGlycolic acid, 2-thio-Mercaptoethanoic acidKyselina thioglykolovaKyselina merkaptooctovaalpha-Mercaptoacetic acidNSC-18947857H94KHMCHEBI:300652-mercaptoethanoic acidRefChem:897804200-677-4Acetic acid, 2-mercapto-mercapto acetic acid

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:30065
ChEMBL:CHEMBL116455
EPA DTXSID:DTXSID8026141
PubMed:23121955
PubMed:23071814
PubMed:23061285
PubMed:23037869
PubMed:23035480
PubMed:22981329
PubMed:22967646
PubMed:22966676
PubMed:22944414
PubMed:22938609
PubMed:22935823
PubMed:22924153

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Records for CAS 68-11-1

1 total

Annex

III

Entry

THIOGLYCOLIC ACID

Thioglycolic acid and its salts

Conditions of use: (a) (b) (c) (d) Avoid contact with eyes Rinse eyes immediately if product comes into contact with them. (a) (c) (d) Wear suitable gloves Warnings to be printed on the label: (a)(i) (b) (c) Contains…

200-677-4

Max concentration

How CAS 68-11-1 is used on this site

CAS 68-11-1 is the Chemical Abstracts Service identifier used to pin this page to a specific substance. In the current dataset, 1 EU annex record shares this identifier, which helps you cross-check whether the same substance appears under one regulatory context or several.

Use this page when a supplier specification, SDS or raw-material dossier gives you CAS 68-11-1 and you need to see every linked Annex II–VI record in one place. The entry cards above are the quickest route to concentration limits, warnings, annex placement and product-type conditions.

Frequently asked questions

A substance identified by CAS 68-11-1 may appear in multiple EU cosmetic regulation annexes when it is subject to different conditions in different contexts. For example, a substance might be restricted under Annex III with specific conditions, and the same CAS might also appear in Annex IV as an approved colorant under separate entry conditions. Each entry must be reviewed individually.

Cross-reference the CAS number against your raw material specification sheets and CoA documents. When a CAS appears in Annex II, verify absence. When it appears in Annex III, verify that concentration limits and product type conditions are met in your formulation. All annex entries sharing this CAS number are listed above.

A CAS number is assigned by the Chemical Abstracts Service (USA) and is globally recognised. An EC number is a European Commission identifier from inventories such as EINECS, ELINCS or the NLP list. Both identifiers may appear in EU cosmetic annex entries. Some substances have both, some have only one, and some older entries may have neither.

The INCI Checker accepts ingredient names, CAS numbers and EC numbers. Check this CAS number directly, then verify the result against supplier specification sheets and every linked annex condition.

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Tools & next steps

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