CosIng Checker
CosIng Checker
EU cosmetic ingredients, restrictions and safety
Login
ProhibitedBinding ruleBROfficial English translationOfficial-source import checked

Boratos, tetraboratos, octaboratos e sais e ésteres do ácido bórico, incluindo octaboratos dissódicos, MEA-borate, MIPA-borate, boratos de potássio, zinco e sódio, bórax e borato fenil mercúrico

ANVISA lists this substance among materials that may not be used in personal-hygiene products, cosmetics or perfumes in Brazil.

All Brazil recordsOpen ingredient profileCompare all marketsOpen official source

Regulatory decision and full conditions

Status
Prohibited
Legal role
Binding rule
Regulatory summary
ANVISA lists this substance among materials that may not be used in personal-hygiene products, cosmetics or perfumes in Brazil.
Conditions and restrictions
Boratos, tetraboratos, octaboratos e sais e ésteres do ácido bórico, incluindo octaboratos dissódicos, MEA-borate, MIPA-borate, boratos de potássio, zinco e sódio, bórax e borato fenil mercúrico

Substance identity

Official source name
Boratos, tetraboratos, octaboratos e sais e ésteres do ácido bórico, incluindo octaboratos dissódicos, MEA-borate, MIPA-borate, boratos de potássio, zinco e sódio, bórax e borato fenil mercúrico
CAS
12008-41-2; 12280-03-4; 10377-81-8; 26038-87-9; 68130-12-1; 68003-13-4; 26038-90-4; 12712-38-8; 1332-07-6; 1330-43-4; 12267-73-1; 13840-56-7; 1303-96-4; 12179-04-3; 102-98-7; 6273-99-0
EC
234-541-0; 233-829-3; 268-109-8; 603-184-6; 215-566-6; 215-540-4; 235-541-3; 237-560-2; 203-068-1; 228-465-7
Identity mapping
cas_number
Linked ingredient
ZINC BORATE
Search this identity across the siteCAS 12008-41-2CAS 12280-03-4CAS 10377-81-8CAS 26038-87-9CAS 68130-12-1CAS 68003-13-4CAS 26038-90-4CAS 12712-38-8CAS 1332-07-6CAS 1330-43-4CAS 12267-73-1CAS 13840-56-7CAS 1303-96-4CAS 12179-04-3CAS 102-98-7CAS 6273-99-0EC 234-541-0EC 233-829-3EC 268-109-8EC 603-184-6EC 215-566-6EC 215-540-4EC 235-541-3EC 237-560-2EC 203-068-1EC 228-465-7

Linked CosIng identity data

Names and aliases

ZINC BORATE

CosIng description: Boric acid, zinc salt

EU inventory restriction note: II/1396

Recorded cosmetic function: SKIN CONDITIONING - HUMECTANT

Function pages:SKIN CONDITIONING - HUMECTANT

View the complete ingredient profile

Cross-market snapshot for this identity

Exact linked records currently present in this site. An absent market means no imported exact match, not permission to use the substance.

8 market datasets
PubChem 2D chemical structure for CAS 102-98-7
CAS 102-98-7PubChem CID 16683761

Verified chemistry for CAS 102-98-7

Phenylmercury borate

IUPAC name
boronooxy(phenyl)mercury
Molecular formula
C6H7BHgO3
Molecular weight
338.52 g/mol
Exact mass
340.019468 Da
Monoisotopic mass
340.019468 Da
Topological polar surface area
49.7 Ų
Molecular complexity
106.0
Formal charge
0
Hydrogen-bond donors
2
Hydrogen-bond acceptors
3
Rotatable bonds
3
Heavy atoms
11
Covalent units
1

Names and synonyms reported to PubChem

FamoseptFenoseptSpidoxolSpidoxRyfenPhenylmercuriboratePhenyl mercuric borateNSC-163948
11 more reported names
phenylhydrargyri borasRefChem:173090203-068-1(dihydrogen borato)phenylmercuryZT1TTY3NGJPhenylmercuriboratMercurate(2-), dihydrogendihydrogen borate;phenylmercury(1+)DB-040400Mercurate(2-), [orthoborato(3-)-.kappa.O]phenyl-, dihydrogenMercurate(2-), [orthoborato(3-)-kappaO]phenyl-, hydrogen (1:2)
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D conformers
0
Machine-readable structure identifiers
SMILES
B(O)(O)O[Hg]C1=CC=CC=C1
InChI
InChI=1S/C6H5.BH2O3.Hg/c1-2-4-6-5-3-1;2-1(3)4;/h1-5H;2-3H;/q;-1;+1
InChIKey
VUXSPDNLYQTOSY-UHFFFAOYSA-N

Evidence from additional scientific databases

NIH PubChem PUG-View
Exact identifier match16683761

Attributed physical-property, hazard, environmental and use annotations.

  • Note: This chemical does not meet GHS hazard criteria for 7% (3 of 43) of reports. Source: European Chemicals Agency (ECHA)
  • Signal: Danger Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H300 (93%): Fatal if swallowed [Danger Acute toxicity, oral]; H310 (93%): Fatal in contact with skin [Danger Acute toxicity, dermal]; H330 (93%): Fatal if inhaled [Danger Acute toxicity, inhalation]; H373 (93%): May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]; H400 (90.7%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]; H410 (90.7%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P260, P262, P264, P270, P271, P273, P280, P284, P301+P316, P302+P352, P304+P340, P316, P319, P320, P321, P330, P361+P364, P391, P403+P233, P405, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 43 reports by companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Reported as not meeting GHS hazard criteria per 3 of 43 reports by companies.; There are 3 notifications provided by 40 of 43 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • Health Effects: Mercury mainly affects the nervous system. Exposure to high levels of metallic, inorganic, or organic mercury can permanently damage the brain, kidneys, and developing fetus. Effects on brain functioning may result in irritability, shyness, tremors, changes in vision or hearing, and memory problems. Acrodynia, a type of mercury poisoning in children, is characterized by pain and pink discoloration of the hands and feet. Mercury poisoning can also cause Hunter-Russell syndrome and Minamata disease. (L7) Source: Toxin and Toxin Target Database (T3DB)
  • Toxicity Summary: High-affinity binding of the divalent mercuric ion to thiol or sulfhydryl groups of proteins is believed to be the major mechanism for the activity of mercury. Through alterations in intracellular thiol status, mercury can promote oxidative stress, lipid peroxidation, mitochondrial dysfunction, and changes in heme metabolism. Mercury is known to bind to microsomal and mitochondrial enzymes, resulting in cell injury and death. For example, mercury is known to inhibit aquaporins, halting water flow across the cell membrane. It also inhibits the protein LCK, which causes decreased T-cell signalling and immune system depression. Mercury is also believed to inhibit neuronal excitability by acting on the postsynaptic neuronal membrane. It also affects the nervous system by inhibiting protein kinase C and alkaline phosphatase, which impairs brain microvascular formation and function, as well as alters the blood-brain barrier. Organic mercury exerts developmental effects by binding to tubulin, preventing microtubule assembly and causing mitotic inhibition. Mercury also produces an autoimmune response, likely by modification of major histocompatibility complex (MHC) class II molecules, self Source: Toxin and Toxin Target Database (T3DB)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
EMBL-EBI ChEBINo exact record2026-08-31
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 10377-81-8
CAS 10377-81-8PubChem CID 82594

Verified chemistry for CAS 10377-81-8

Monoethanolamine borate

IUPAC name
2-aminoethoxyboronic acid
Molecular formula
C2H8BNO3
Molecular weight
104.90 g/mol
Exact mass
105.0597233 Da
Monoisotopic mass
105.0597233 Da
Topological polar surface area
75.7 Ų
Molecular complexity
41.0
Formal charge
0
Hydrogen-bond donors
3
Hydrogen-bond acceptors
4
Rotatable bonds
3
Heavy atoms
7
Covalent units
1

Names and synonyms reported to PubChem

Actracor MMEA-BorateEthanolamine borate (1:1)Ethanol, 2-amino-, monoester with boric acid (H3BO3)Ethanol, 2-amino-, ester with boric acid (H3BO3) (1:1)5I4T660488RefChem:1089826233-829-3
12 more reported names
Ethanolamine borateTrigamine2-Aminoethanol, monoester with boric acidBoric acid, 2-aminoethyl ester2-aminoethyl dihydrogen borateUNII-5I4T660488EINECS 233-829-3EC 233-829-3boric acid-beta-aminoethylesterJCAYXDKNUSEQRT-UHFFFAOYSA-NBC 140Ethanol, 2-amino-, monoester with boric acid
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D conformers
0
Machine-readable structure identifiers
SMILES
B(O)(O)OCCN
InChI
InChI=1S/C2H8BNO3/c4-1-2-7-3(5)6/h5-6H,1-2,4H2
InChIKey
JCAYXDKNUSEQRT-UHFFFAOYSA-N

Evidence from additional scientific databases

NIH PubChem PUG-View
Exact identifier match82594

Attributed physical-property, hazard, environmental and use annotations.

  • Note: This chemical does not meet GHS hazard criteria for 29.7% (11 of 37) of reports. Source: European Chemicals Agency (ECHA)
  • Signal: Warning Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H315 (70.3%): Causes skin irritation [Warning Skin corrosion/irritation]; H319 (70.3%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H335 (67.6%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 37 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Reported as not meeting GHS hazard criteria per 11 of 37 reports by companies.; There are 2 notifications provided by 26 of 37 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
EMBL-EBI ChEBINo exact record2026-08-31
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 12008-41-2
CAS 12008-41-2PubChem CID 90479350

Verified chemistry for CAS 12008-41-2

Boron sodium oxide (B8Na2O13)

IUPAC name
disodium;(9,11-dioxido-5-oxoboranyloxy-2,4,6,8,10,12,13-heptaoxa-1,3,5,7,9,11-hexaborabicyclo[5.5.1]tridecan-3-yl)oxy-oxoborane
Molecular formula
B8Na2O13
Molecular weight
340.5 g/mol
Exact mass
340.9915016 Da
Monoisotopic mass
341.987870 Da
Topological polar surface area
163.0 Ų
Molecular complexity
319.0
Formal charge
0
Hydrogen-bond donors
0
Hydrogen-bond acceptors
13
Rotatable bonds
2
Heavy atoms
23
Covalent units
3

Names and synonyms reported to PubChem

Disodium octaborateImpelBORA-CAREJT9XWY98MFSodium borate (Na2B8O13)Boron sodium oxide (Na2B8O13)Boric acid (H2B8O13), disodium saltRefChem:1080103
12 more reported names
234-541-0602-894-3BORACOL-40Boracol 40UNII-JT9XWY98MFSodium borate(B8Na2O13)Sodium octaborate (Na2B8O13)HSDB 7707EINECS 234-541-0EC 234-541-0CGCGPGRQKOPVHP-UHFFFAOYSA-NDisodium 9,11-bis[(oxoboranyl)oxy]bicyclo[5.5.1]hexaboroxane-3,5-bis(olate)
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D conformers
0
Machine-readable structure identifiers
SMILES
B(=O)OB1OB2OB(OB(OB(O2)OB(O1)OB=O)[O-])[O-].[Na+].[Na+]
InChI
InChI=1S/B8O13.2Na/c9-1-13-5-18-6(14-2-10)20-8-17-4(12)15-3(11)16-7(19-5)21-8;;/q-2;2*+1
InChIKey
CGCGPGRQKOPVHP-UHFFFAOYSA-N

Evidence from additional scientific databases

NIH PubChem PUG-View
Exact identifier match90479350

Attributed physical-property, hazard, environmental and use annotations.

  • Toxicity Summary: The inorganic borates display low acute toxicity. They are either not irritant or mild skin and eye irritants. They are not skin sensitisers, nor are they mutagenic or carcinogenic. The most sensitive endpoints of toxicity are considered to be effects on the reproductive organs, fertility in males, and developmental effects. The doses that cause these effects are far higher than any levels to which the human population could be exposed... /Inorganic borates/ Source: Hazardous Substances Data Bank (HSDB)
  • Uses: For disodium octaborate (USEPA/OPP Pesticide Code: 011107) ACTIVE products with label matches. /SRP: Registered for use in the U.S. but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses./ Source: Hazardous Substances Data Bank (HSDB)
  • Uses: For disodium octaborate tetrahydrate (USEPA/OPP Pesticide Code: 011103) ACTIVE products with label matches. /SRP: Registered for use in the U.S. but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses./ /Disodium octaborate tetrahydrate/ Source: Hazardous Substances Data Bank (HSDB)
  • Uses: Used to prevent and control decay fungi in lumber and timber products. Source: Hazardous Substances Data Bank (HSDB)
  • Uses: Multimicronutrient fertilizer /Disodium octaborate tetrahydrate/ Source: Hazardous Substances Data Bank (HSDB)
  • Uses: For more Uses (Complete) data for DISODIUM OCTABORATE (8 total), please visit the HSDB record page. Source: Hazardous Substances Data Bank (HSDB)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 12179-04-3
CAS 12179-04-3PubChem CID 86341921

Verified chemistry for CAS 12179-04-3

Sodium tetraborate pentahydrate

IUPAC name
disodium;[oxido(oxoboranyloxy)boranyl]oxy-oxoboranyloxyborinate;pentahydrate
Molecular formula
B4H10Na2O12
Molecular weight
291.3 g/mol
Exact mass
292.0339850 Da
Monoisotopic mass
292.0339850 Da
Topological polar surface area
113.0 Ų
Molecular complexity
110.0
Formal charge
0
Hydrogen-bond donors
5
Hydrogen-bond acceptors
12
Rotatable bonds
4
Heavy atoms
18
Covalent units
8

Names and synonyms reported to PubChem

Sodium borate, pentahydrateSG2N20S03UBoron sodium oxide(B4Na2O7), pentahydrateBoric acid(H2B4O7), disodium salt, pentahydrateRefChem:887925601-808-1Boron sodium oxide (B4Na2O7), hydrate (1:5)Disodium tetraborate pentahydrate
6 more reported names
UNII-SG2N20S03UBoron sodium oxide (B4Na2O7), pentahydrateEC 215-540-4Boric acid (H2B4O7), disodium salt, pentaborateBoron sodium oxide pentahydrateQZSYXKPOZFXCDM-UHFFFAOYSA-N
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D conformers
0
Machine-readable structure identifiers
SMILES
B(=O)OB([O-])OB([O-])OB=O.O.O.O.O.O.[Na+].[Na+]
InChI
InChI=1S/B4O7.2Na.5H2O/c5-1-9-3(7)11-4(8)10-2-6;;;;;;;/h;;;5*1H2/q-2;2*+1;;;;;
InChIKey
QZSYXKPOZFXCDM-UHFFFAOYSA-N

Evidence from additional scientific databases

NIH PubChem PUG-View
Exact identifier match86341921

Attributed physical-property, hazard, environmental and use annotations.

  • First Aid: (General first aid procedures); Eye: Irrigate immediately - If this chemical contacts the eyes, immediately wash (irrigate) the eyes with large amounts of water, occasionally lifting the lower and upper lids. Get medical attention immediately.; Skin: Soap wash - If this chemical contacts the skin, wash the contaminated skin with soap and water.; Breathing: Respiratory support; Swallow: Medical attention immediately - If this chemical has been swallowed, get medical attention immediately. Source: The National Institute for Occupational Safety and Health (NIOSH)
  • Industry Uses: Anti-adhesive/cohesive; Plating agent; Flame retardant; Corrosion inhibitor; Not Known or Reasonably Ascertainable; Etching agent; Chelating agent; Defoamer Source: EPA Chemical Data Reporting (CDR)
  • Sources/Uses: Used as a preservative, antiseptic and fungicide; also used to manufacture glazes, enamels, soldering fluxes and cleaning compounds and to fireproof textiles and wood; [ACGIH] Boric acid and borates as tablets or powder are used to kill larvae in barns and other insects in houses. Rarely, they are sprayed as herbicides. [EPA: Recognition of Pesticide Poisonings] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
  • Industrial Processes with risk of exposure: Soldering [Category: Heat or Machine]; Using Disinfectants or Biocides [Category: Clean]; Farming (Pesticides) [Category: Industry]; Textiles (Printing, Dyeing, or Finishing) [Category: Industry] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 12267-73-1
CAS 12267-73-1PubChem CID 10219853

Verified chemistry for CAS 12267-73-1

Sodium Tetraborate

IUPAC name
disodium;3,7-dioxido-2,4,6,8,9-pentaoxa-1,3,5,7-tetraborabicyclo[3.3.1]nonane
Molecular formula
B4Na2O7
Molecular weight
201.2 g/mol
Exact mass
201.9811616 Da
Monoisotopic mass
201.9811616 Da
Topological polar surface area
92.3 Ų
Molecular complexity
121.0
Formal charge
0
Hydrogen-bond donors
0
Hydrogen-bond acceptors
7
Rotatable bonds
0
Heavy atoms
13
Covalent units
3

Names and synonyms reported to PubChem

1330-43-4Sodium Tetraborate, AnhydrousBorax glassBoron sodium oxide (B4Na2O7)Anhydrous boraxSodium biborateBorax AnhydrousFused borax
16 more reported names
Sodium borate anhydrousBorax, fusedSodium pyroborateDehyborGranuborSprayborSodium borate, anhydrousBorax, dehydratedSodium boron oxideRasorite 658191EN8ZMDBoric acid, disodium saltBoric acid (H2B4O7), disodium saltSodium tetraborate anhydrousINS NO.285Sodium boron oxide (na2b4o7)
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D conformers
0
Machine-readable structure identifiers
SMILES
B1(OB2OB(OB(O1)O2)[O-])[O-].[Na+].[Na+]
InChI
InChI=1S/B4O7.2Na/c5-1-7-3-9-2(6)10-4(8-1)11-3;;/q-2;2*+1
InChIKey
UQGFMSUEHSUPRD-UHFFFAOYSA-N

Evidence from additional scientific databases

NIH PubChem PUG-View
Exact identifier match10219853

Attributed physical-property, hazard, environmental and use annotations.

  • First Aid: (General first aid procedures); Eye: Irrigate immediately - If this chemical contacts the eyes, immediately wash (irrigate) the eyes with large amounts of water, occasionally lifting the lower and upper lids. Get medical attention immediately.; Skin: Soap wash - If this chemical contacts the skin, wash the contaminated skin with soap and water.; Breathing: Respiratory support; Swallow: Medical attention immediately - If this chemical has been swallowed, get medical attention immediately. Source: The National Institute for Occupational Safety and Health (NIOSH)
  • Signal: Danger Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • GHS Hazard Statements: H360FD: May damage fertility; May damage the unborn child [Danger Reproductive toxicity] Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • Precautionary Statement Codes: P203, P280, P318, P405, and P501 (click each P-code to see the statement) Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • Signal: Danger Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H319 (53.2%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H360 (88.5%): May damage fertility or the unborn child [Danger Reproductive toxicity]; H360FD (22.3%): May damage fertility; May damage the unborn child [Danger Reproductive toxicity] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P203, P264+P265, P280, P305+P351+P338, P318, P337+P317, P405, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 1733 reports by companies from 44 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • Signal: Danger Source: NITE-CMC
  • GHS Hazard Statements: H315: Causes skin irritation [Warning Skin corrosion/irritation]; H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]; H360: May damage fertility or the unborn child [Danger Reproductive toxicity]; H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure]; H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure] Source: NITE-CMC
  • Precautionary Statement Codes: P203, P260, P261, P264, P264+P265, P270, P271, P280, P302+P352, P304+P340, P305+P351+P338, P308+P316, P318, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement) Source: NITE-CMC
  • GHS Hazard Statements: H320: Causes eye irritation [Warning Serious eye damage/eye irritation]; H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]; H360: May damage fertility or the unborn child [Danger Reproductive toxicity]; H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure]; H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure]; H373: May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]; H402: Harmful to aquatic life [Hazardous to the aquatic environment, acute hazard]; H412: Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard] Source: NITE-CMC
  • Precautionary Statement Codes: P203, P260, P261, P264, P264+P265, P270, P271, P273, P280, P304+P340, P305+P351+P338, P308+P316, P318, P319, P321, P337+P317, P403+P233, P405, and P501 (click each P-code to see the statement) Source: NITE-CMC
  • Environmental Fate: Terrestrial Fate: Average persistence at recommended rates is one or more years, depending on soil type and rainfall. Less persistent in acid soils and in high rainfall areas. Source: Hazardous Substances Data Bank (HSDB)
  • Consumer Uses: Adhesion/cohesion promoter; Flux agent; Soil amendments (fertilizers); Filler; Not Known or Reasonably Ascertainable; Bleaching agent; Anti-freeze agent; Other Source: EPA Chemical Data Reporting (CDR)
  • Industry Uses: Processing aids not otherwise specified; Bleaching agent; Anti-freeze agent; Other; Heat stabilizer; Hardener; Adhesion/cohesion promoter; Flame retardant; Flux agent; Filler; Soil amendments (fertilizers) Source: EPA Chemical Data Reporting (CDR)
  • Sources/Uses: Used as tablets or powder to kill larvae in livestock confinements and crawling insects in residences; [EPA Pesticides] Used as a fluxing agent, a buffering agent, a biocide (preservative, antiseptic, insecticide, fungicide, herbicide, algicide, nematicide), a fireproofing agent, a corrosion inhibitor, a tanning agent, and a textile bleaching agent; Used to manufacture glazes, enamels, borosilicate glass, fertilizers, detergents, antifreeze, pharmaceuticals, and cosmetics; [HSDB] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
  • Industrial Processes with risk of exposure: Acid and Alkali Cleaning of Metals [Category: Clean]; Using Disinfectants or Biocides [Category: Clean]; Farming (Pesticides) [Category: Industry]; Glass Manufacturing [Category: Industry] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
  • Uses: For sodium tetraborate (USEPA/OPP Pesticide Code: 011112) ACTIVE products with label matches. /SRP: Registered for use in the U.S. but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses./ Source: Hazardous Substances Data Bank (HSDB)
  • Uses: Manufacture of glass, enamels, & other ceramic products Source: Hazardous Substances Data Bank (HSDB)
  • Uses: Soldering metals; manufacture of glazes and enamels; tanning; in cleaning compounds; artificially aging wood; ...curing and preserving skins Source: Hazardous Substances Data Bank (HSDB)
  • Uses: As preservative either alone or with other antiseptics against wood fungus; fireproofing fabrics & wood Source: Hazardous Substances Data Bank (HSDB)
  • Uses: For more Uses (Complete) data for SODIUM TETRABORATE (15 total), please visit the HSDB record page. Source: Hazardous Substances Data Bank (HSDB)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 12280-03-4
CAS 12280-03-4PubChem CID 90478478

Verified chemistry for CAS 12280-03-4

Disodium octaborate tetrahydrate

IUPAC name
disodium;(9,11-dioxido-5-oxoboranyloxy-2,4,6,8,10,12,13-heptaoxa-1,3,5,7,9,11-hexaborabicyclo[5.5.1]tridecan-3-yl)oxy-oxoborane;tetrahydrate
Molecular formula
B8H8Na2O17
Molecular weight
412.5 g/mol
Exact mass
413.0337604 Da
Monoisotopic mass
414.030129 Da
Topological polar surface area
167.0 Ų
Molecular complexity
319.0
Formal charge
0
Hydrogen-bond donors
4
Hydrogen-bond acceptors
17
Rotatable bonds
2
Heavy atoms
27
Covalent units
7

Names and synonyms reported to PubChem

TimborTim-BorBoron sodium oxide tetrahydrateFLEABORU2EEC8170GBoron sodium oxide, tetrahydrateEPA Pesticide Chemical Code 011103Boric acid, disodium salt, tetrahydrate
16 more reported names
Boric acid (H2B8O13), disodium salt, tetrahydrateRefChem:135076disodium octaborate tetrahydrate, Na2B8O13sodium 9,11-bis((oxoboryl)oxy)bicyclo(5.5.1)hexaboroxane-3,5-diolate hydrate (2:1:4)BORACOLBoron sodium oxide (B8Na2O13), tetrahydrateCELLU-TREATMOP UPNIBOR-DCaswell No. 406BUNII-U2EEC8170GB8H8Na2O17Disodium octaborate, tetrahydrateRDMZIKMKSGCBKK-UHFFFAOYSA-NSodium 9,11-bis[(oxoboranyl)oxy]bicyclo[5.5.1]hexaboroxane-3,5-bis(olate)--water (2/1/4)disodium;(9,11-dioxido-5-oxoboranyloxy-2,4,6,8,10,12,13-heptaoxa-1,3,5,7,9,11-hexaborabicyclo[5.5.1]tridecan-3-yl)oxy-oxo-borane;tetrahydrate
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D conformers
0
Machine-readable structure identifiers
SMILES
B(=O)OB1OB2OB(OB(OB(O2)OB(O1)OB=O)[O-])[O-].O.O.O.O.[Na+].[Na+]
InChI
InChI=1S/B8O13.2Na.4H2O/c9-1-13-5-18-6(14-2-10)20-8-17-4(12)15-3(11)16-7(19-5)21-8;;;;;;/h;;;4*1H2/q-2;2*+1;;;;
InChIKey
RDMZIKMKSGCBKK-UHFFFAOYSA-N

Evidence from additional scientific databases

NIH PubChem PUG-View
Exact identifier match90478478

Attributed physical-property, hazard, environmental and use annotations.

  • Signal: Danger Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • GHS Hazard Statements: H360FD: May damage fertility; May damage the unborn child [Danger Reproductive toxicity] Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • Precautionary Statement Codes: P203, P280, P318, P405, and P501 (click each P-code to see the statement) Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • Note: This chemical does not meet GHS hazard criteria for 7.1% (2 of 28) of reports. Source: European Chemicals Agency (ECHA)
  • Signal: Danger Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H315 (14.3%): Causes skin irritation [Warning Skin corrosion/irritation]; H319 (71.4%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H360 (78.6%): May damage fertility or the unborn child [Danger Reproductive toxicity] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P203, P264, P264+P265, P280, P302+P352, P305+P351+P338, P318, P321, P332+P317, P337+P317, P362+P364, P405, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 28 reports by companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Reported as not meeting GHS hazard criteria per 2 of 28 reports by companies.; There are 3 notifications provided by 26 of 28 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • Signal: Danger Source: NITE-CMC
  • GHS Hazard Statements: H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]; H360: May damage fertility or the unborn child [Danger Reproductive toxicity]; H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure]; H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure]; H373: May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure] Source: NITE-CMC
  • Precautionary Statement Codes: P203, P260, P261, P264, P270, P271, P280, P304+P340, P308+P316, P318, P319, P321, P403+P233, P405, and P501 (click each P-code to see the statement) Source: NITE-CMC
  • Signal: Danger Source: Hazardous Chemical Information System (HCIS), Safe Work Australia

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 12712-38-8
CAS 12712-38-8PubChem CID 12816516

Verified chemistry for CAS 12712-38-8

boric acid, potassium salt

IUPAC name
tripotassium;borate
Molecular formula
BK3O3
Molecular weight
176.11 g/mol
Exact mass
175.8851685 Da
Monoisotopic mass
175.8851685 Da
Topological polar surface area
69.2 Ų
Molecular complexity
8.0
Formal charge
0
Hydrogen-bond donors
0
Hydrogen-bond acceptors
3
Rotatable bonds
0
Heavy atoms
7
Covalent units
4

Names and synonyms reported to PubChem

tripotassium borateK3BO3CHEBI:38911RefChem:121013603-184-6Potassium boratePOTASSIUMBORATEBoric acid potassium salt
4 more reported names
Potassium borate (K3BO3)3LZ8H5J279Boric acid (H3BO3), tripotassium saltDB-254092
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D conformers
0
Machine-readable structure identifiers
SMILES
B([O-])([O-])[O-].[K+].[K+].[K+]
InChI
InChI=1S/BO3.3K/c2-1(3)4;;;/q-3;3*+1
InChIKey
WUUHFRRPHJEEKV-UHFFFAOYSA-N

Evidence from additional scientific databases

NIH PubChem PUG-View
Exact identifier match12816516

Attributed physical-property, hazard, environmental and use annotations.

  • Signal: Danger Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H315 (71%): Causes skin irritation [Warning Skin corrosion/irritation]; H319 (71%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H335 (35.5%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]; H360 (29%): May damage fertility or the unborn child [Danger Reproductive toxicity] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P203, P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P318, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 62 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • Signal: Danger Source: Hazardous Chemical Information System (HCIS), Safe Work Australia
  • GHS Hazard Statements: H360FD: May damage fertility; May damage the unborn child [Danger Reproductive toxicity] Source: Hazardous Chemical Information System (HCIS), Safe Work Australia
  • Precautionary Statement Codes: P203, P280, P318, P405, and P501 (click each P-code to see the statement) Source: Hazardous Chemical Information System (HCIS), Safe Work Australia

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 1303-96-4
CAS 1303-96-4PubChem CID 16211214

Verified chemistry for CAS 1303-96-4

Borax (B4Na2O7.10H2O)

IUPAC name
disodium;3,7-dioxido-2,4,6,8,9-pentaoxa-1,3,5,7-tetraborabicyclo[3.3.1]nonane;decahydrate
Molecular formula
B4H20Na2O17
Molecular weight
381.4 g/mol
Exact mass
382.0868084 Da
Monoisotopic mass
382.0868084 Da
Topological polar surface area
102.0 Ų
Molecular complexity
121.0
Formal charge
0
Hydrogen-bond donors
10
Hydrogen-bond acceptors
17
Rotatable bonds
0
Heavy atoms
23
Covalent units
13

Names and synonyms reported to PubChem

BORAXBorax decahydrateSodium borate decahydrateSodium pyroborate decahydrateAntipyoninBorascuBoricinSolubor
16 more reported names
TronaborJaikinNeoborBuraGerstley borateGertley borateBoro-spray91MBZ8H3QODisodium tetraborate decahydrateSodium borate, decahydrateSodium biborate decahydrateBoric acid (H2B4O7), disodium salt, decahydrateBoron sodium oxide (B4Na2O7), decahydratesodium diboratesodium meta borateBorax 200ck
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D conformers
0
Machine-readable structure identifiers
SMILES
B1(OB2OB(OB(O1)O2)[O-])[O-].O.O.O.O.O.O.O.O.O.O.[Na+].[Na+]
InChI
InChI=1S/B4O7.2Na.10H2O/c5-1-7-3-9-2(6)10-4(8-1)11-3;;;;;;;;;;;;/h;;;10*1H2/q-2;2*+1;;;;;;;;;;
InChIKey
CDMADVZSLOHIFP-UHFFFAOYSA-N

Evidence from additional scientific databases

NIH PubChem PUG-View
Exact identifier match16211214

Attributed physical-property, hazard, environmental and use annotations.

  • First Aid: (General first aid procedures); Eye: Irrigate immediately - If this chemical contacts the eyes, immediately wash (irrigate) the eyes with large amounts of water, occasionally lifting the lower and upper lids. Get medical attention immediately.; Skin: Soap wash - If this chemical contacts the skin, wash the contaminated skin with soap and water.; Breathing: Respiratory support; Swallow: Medical attention immediately - If this chemical has been swallowed, get medical attention immediately. Source: The National Institute for Occupational Safety and Health (NIOSH)
  • Signal: Danger Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • GHS Hazard Statements: H360FD: May damage fertility; May damage the unborn child [Danger Reproductive toxicity] Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • Precautionary Statement Codes: P203, P280, P318, P405, and P501 (click each P-code to see the statement) Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • Note: This chemical does not meet GHS hazard criteria for < 0.1% (1 of 2865) of reports. Source: European Chemicals Agency (ECHA)
  • Signal: Danger Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H319 (12.6%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H360 (93.2%): May damage fertility or the unborn child [Danger Reproductive toxicity] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P203, P264+P265, P280, P305+P351+P338, P318, P337+P317, P405, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 2865 reports by companies from 31 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Reported as not meeting GHS hazard criteria per 1 of 2865 reports by companies.; There are 30 notifications provided by 2864 of 2865 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • Signal: Danger Source: NITE-CMC
  • GHS Hazard Statements: H315: Causes skin irritation [Warning Skin corrosion/irritation]; H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]; H360: May damage fertility or the unborn child [Danger Reproductive toxicity]; H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure]; H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure]; H413: May cause long lasting harmful effects to aquatic life [Hazardous to the aquatic environment, long-term hazard] Source: NITE-CMC
  • Precautionary Statement Codes: P203, P260, P261, P264, P264+P265, P270, P271, P273, P280, P302+P352, P304+P340, P305+P351+P338, P308+P316, P318, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement) Source: NITE-CMC
  • GHS Hazard Statements: H303: May be harmful if swallowed [Warning Acute toxicity, oral]; H315: Causes skin irritation [Warning Skin corrosion/irritation]; H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H361: Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]; H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure]; H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure]; H373: May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure] Source: NITE-CMC
  • Cosmetic Ingredient Review Conclusion: The Expert Panel concludes that Sodium Borate and Boric Acid, in concentrations less than or equal to 5 percent, are safe as cosmetic ingredients when used as currently recommended; however, cosmetic formulations containing free Sodium Borate or Boric Acid at this concentration should not be used on infant skin or injured skin. Note: In 2003, the CIR Expert Panel considered available new data on these ingredients and reaffirmed the above conclusion. Source: Cosmetic Ingredient Review (CIR)
  • Cosmetic Ingredient Review Finding(s): Safe for use in cosmetics, with qualifications Source: Cosmetic Ingredient Review (CIR)
  • Environmental Bioconcentration: In a greenhouse experiment with sandy loam soil treated with 0-8.0 ppm boron as borax, boron toxicity symptoms appeared earliest in lentil plants and barley seedlings exposed to 8.0 ppm boron. In barley the severity of boron toxicity decreased with the decrease in boron levels, whereas in lentil the severity of the symptoms eventually reached the same level in 2 and 4 ppm boron treatments as with the highest concentration. Dry matter yield decreased 38.6% in lentil and 23.4% in barley exposed to 8.0 ppm boron in comparison with controls. Boron contents of lentil and barley plants on soil treated with 8 ppm boron were approximately 7- and approximately 8-fold those of control plants, respectively. Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: TERRESTRIAL FATE: Boron is naturally occurring and ubiquitous in the environment. No microbial degradation. Disappearance from soil is by washing out. Persistence in soil is about 2 years, depending on rainfall and soil structure. Source: Hazardous Substances Data Bank (HSDB)
  • Consumer Uses: Other; Adhesion/cohesion promoter; Soil amendments (fertilizers); Not Known or Reasonably Ascertainable; Flame retardant Source: EPA Chemical Data Reporting (CDR)
  • Cosmetic Ingredient Review Link: CIR ingredient: Sodium Borate Source: Cosmetic Ingredient Review (CIR)
  • Sources/Uses: Used as a preservative, antiseptic and fungicide; also used to manufacture glazes, enamels, soldering fluxes and cleaning compounds and to fireproof textiles and wood; [ACGIH] Boric acid and borates as tablets or powder are used to kill larvae in barns and other insects in houses. Rarely, they are sprayed as herbicides. [EPA: Recognition of Pesticide Poisonings] Used in photo developing bath; [www.ci.tucson.az.us/arthazards/medium.html] Borax (borax decahydrate) is found naturally in some salt lakes and alkaline soils. Boric acid is formed by crystallizing a solution of hydrochloric acid or sulfuric acid and borax. [Hawley] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
  • Industrial Processes with risk of exposure: Soldering [Category: Heat or Machine]; Using Disinfectants or Biocides [Category: Clean]; Farming (Pesticides) [Category: Industry]; Photographic Processing [Category: Other]; Textiles (Printing, Dyeing, or Finishing) [Category: Industry] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
  • Uses: For borax (USEPA/OPP Pesticide Code: 011102) ACTIVE products with label matches. /SRP: Registered for use in the U.S. but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses./ Source: Hazardous Substances Data Bank (HSDB)
  • Uses: Long been used as a mild antiseptic fungicide and as a herbicide ... Total control of vegetation on non-crop land, such as paths, giving long-term control. Also used in insect baits for food stores to control Formicidae. Source: Hazardous Substances Data Bank (HSDB)
  • Uses: Soldering metals; manufacture of glazes and enamels; tanning; in cleaning compounds; artificially aging wood; as preservative, either alone or with other antiseptics against wood fungus; fireproofing fabrics and wood; curing and preserving skins; in cockroach control. In buffers; as a complexing or masking agent in analytical chemistry. Pharmaceutic aid (alkalizer). Source: Hazardous Substances Data Bank (HSDB)
  • Uses: Used in ant poisons, for fly control around refuse and manure piles, as a larvicide, in manufacture of glazes, enamels, cleaning compounds, and in soldering metals Source: Hazardous Substances Data Bank (HSDB)
  • Uses: For more Uses (Complete) data for BORAX (17 total), please visit the HSDB record page. Source: Hazardous Substances Data Bank (HSDB)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 1330-43-4
CAS 1330-43-4PubChem CID 10219853

Verified chemistry for CAS 1330-43-4

Sodium Tetraborate

IUPAC name
disodium;3,7-dioxido-2,4,6,8,9-pentaoxa-1,3,5,7-tetraborabicyclo[3.3.1]nonane
Molecular formula
B4Na2O7
Molecular weight
201.2 g/mol
Exact mass
201.9811616 Da
Monoisotopic mass
201.9811616 Da
Topological polar surface area
92.3 Ų
Molecular complexity
121.0
Formal charge
0
Hydrogen-bond donors
0
Hydrogen-bond acceptors
7
Rotatable bonds
0
Heavy atoms
13
Covalent units
3

Names and synonyms reported to PubChem

Sodium Tetraborate, AnhydrousBorax glassBoron sodium oxide (B4Na2O7)Anhydrous boraxSodium biborateBorax AnhydrousFused boraxSodium borate anhydrous
16 more reported names
Borax, fusedSodium pyroborateDehyborGranuborSprayborSodium borate, anhydrousBorax, dehydratedSodium boron oxideRasorite 658191EN8ZMDBoric acid, disodium saltBoric acid (H2B4O7), disodium saltSodium tetraborate anhydrousINS NO.285Sodium boron oxide (na2b4o7)INS-285
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D conformers
0
Machine-readable structure identifiers
SMILES
B1(OB2OB(OB(O1)O2)[O-])[O-].[Na+].[Na+]
InChI
InChI=1S/B4O7.2Na/c5-1-7-3-9-2(6)10-4(8-1)11-3;;/q-2;2*+1
InChIKey
UQGFMSUEHSUPRD-UHFFFAOYSA-N

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 13840-56-7
CAS 13840-56-7PubChem CID 160998

Verified chemistry for CAS 13840-56-7

Boric acid (H3BO3), sodium salt (1:?)

IUPAC name
sodium borate
Molecular formula
BNaO3-2
Formula without charge
BNaO3
Molecular weight
81.80 g/mol
Exact mass
81.9838183 Da
Monoisotopic mass
81.9838183 Da
Topological polar surface area
69.2 Ų
Molecular complexity
8.0
Formal charge
-2
Hydrogen-bond donors
0
Hydrogen-bond acceptors
3
Rotatable bonds
0
Heavy atoms
5
Covalent units
2

Names and synonyms reported to PubChem

Boric acid (H3BO3), sodium saltTrisodium orthoborateOrthoboric acid, sodium saltEINECS 238-253-6EINECS 237-560-2RefChem:569982237-560-2238-253-6
2 more reported names
sodium;borateWJZOJDGNGVXSIK-UHFFFAOYSA-N
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D conformers
0
Machine-readable structure identifiers
SMILES
B([O-])([O-])[O-].[Na+]
InChI
InChI=1S/BO3.Na/c2-1(3)4;/q-3;+1
InChIKey
WJZOJDGNGVXSIK-UHFFFAOYSA-N

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 26038-87-9
CAS 26038-87-9PubChem CID 162220

Verified chemistry for CAS 26038-87-9

(2-Hydroxyethyl)ammonium dihydrogen orthoborate

IUPAC name
2-aminoethanol;boric acid
Molecular formula
C2H10BNO4
Molecular weight
122.92 g/mol
Exact mass
123.0702880 Da
Monoisotopic mass
123.0702880 Da
Topological polar surface area
107.0 Ų
Molecular complexity
18.0
Formal charge
0
Hydrogen-bond donors
5
Hydrogen-bond acceptors
5
Rotatable bonds
1
Heavy atoms
8
Covalent units
2

Names and synonyms reported to PubChem

Orthoboric acid ethanolamine saltOrthoboric acid ethanolamine salt (1:1)Boric acid, 2-aminoethanol saltMonoethanolamine, boric acid saltC059V2S82POrthoboric acid, compound with 2-aminoethanolEINECS 247-421-8EINECS 270-367-1
10 more reported names
EINECS 271-606-2Boric acid, monoethanolamine salt (1:1)EC 247-421-8RefChem:395909247-421-8271-606-2ethanolamine-boric acidUNII-C059V2S82PQIDCRGDFWRMBJC-UHFFFAOYSA-NBoric acid--2-aminoethan-1-ol (1/1)
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D conformers
0
Machine-readable structure identifiers
SMILES
B(O)(O)O.C(CO)N
InChI
InChI=1S/C2H7NO.BH3O3/c3-1-2-4;2-1(3)4/h4H,1-3H2;2-4H
InChIKey
QIDCRGDFWRMBJC-UHFFFAOYSA-N

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 26038-90-4
CAS 26038-90-4PubChem CID 161513

Verified chemistry for CAS 26038-90-4

(2-Hydroxypropyl)ammonium dihydrogen orthoborate

IUPAC name
1-aminopropan-2-ol;boric acid
Molecular formula
C3H12BNO4
Molecular weight
136.95 g/mol
Exact mass
137.0859380 Da
Monoisotopic mass
137.0859380 Da
Topological polar surface area
107.0 Ų
Molecular complexity
30.0
Formal charge
0
Hydrogen-bond donors
5
Hydrogen-bond acceptors
5
Rotatable bonds
1
Heavy atoms
9
Covalent units
2

Names and synonyms reported to PubChem

Orthoboric acid isopropanolamine saltYK5M7W95MCEINECS 247-422-31-Aminopropan-2-ol, compound with orthoboric acidRefChem:395926268-109-8Boric acid, monoisopropanolamine salt2-Hydroxypropylammonium orthoborate
5 more reported names
Isopropanolamine borateUNII-YK5M7W95MCFWGLAJMZAXEFTA-UHFFFAOYSA-NEINECS 268-109-8Boric acid--1-aminopropan-2-ol (1/1)
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
1
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D conformers
0
Machine-readable structure identifiers
SMILES
B(O)(O)O.CC(CN)O
InChI
InChI=1S/C3H9NO.BH3O3/c1-3(5)2-4;2-1(3)4/h3,5H,2,4H2,1H3;2-4H
InChIKey
FWGLAJMZAXEFTA-UHFFFAOYSA-N

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 6273-99-0
CAS 6273-99-0PubChem CID 16683655

Verified chemistry for CAS 6273-99-0

Mercury, [mu-[orthoborato(2-)-O:O']]diphenyldi-

IUPAC name
[hydroxy(phenylmercuriooxy)boranyl]oxy-phenylmercury
Molecular formula
C12H11BHg2O3
Molecular weight
615.21 g/mol
Exact mass
616.019095 Da
Monoisotopic mass
618.02141 Da
Topological polar surface area
38.7 Ų
Molecular complexity
199.0
Formal charge
0
Hydrogen-bond donors
1
Hydrogen-bond acceptors
3
Rotatable bonds
6
Heavy atoms
18
Covalent units
1

Names and synonyms reported to PubChem

Mercury, [.mu.-[orthoborato(2-)-O:O']]diphenyldi-Mercury, (mu-(orthoborato(2-)-O:O'))diphenyldi-MercurylMersolite 90EINECS 228-465-7AI3-60045(mu-(Orthoborato(2-)-O:O'))diphenyldimercuryMercury, [.mu.-(hydrogen orthoborato)]diphenyldi-
4 more reported names
NSC 35683NSC-35683Mercury, (u-(orthoborato(2-)-O:O'))diphenyldi-(mu-Hydrogen-kappaO:kappaO' borato)diphenyldimercury
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D conformers
0
Machine-readable structure identifiers
SMILES
B(O)(O[Hg]C1=CC=CC=C1)O[Hg]C2=CC=CC=C2
InChI
InChI=1S/2C6H5.BHO3.2Hg/c2*1-2-4-6-5-3-1;2-1(3)4;;/h2*1-5H;2H;;/q;;-2;2*+1
InChIKey
HCIUVGKUNYOVBM-UHFFFAOYSA-N

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 68003-13-4
CAS 68003-13-4PubChem CID 161513

Verified chemistry for CAS 68003-13-4

(2-Hydroxypropyl)ammonium dihydrogen orthoborate

IUPAC name
1-aminopropan-2-ol;boric acid
Molecular formula
C3H12BNO4
Molecular weight
136.95 g/mol
Exact mass
137.0859380 Da
Monoisotopic mass
137.0859380 Da
Topological polar surface area
107.0 Ų
Molecular complexity
30.0
Formal charge
0
Hydrogen-bond donors
5
Hydrogen-bond acceptors
5
Rotatable bonds
1
Heavy atoms
9
Covalent units
2

Names and synonyms reported to PubChem

Orthoboric acid isopropanolamine saltYK5M7W95MCEINECS 247-422-31-Aminopropan-2-ol, compound with orthoboric acidRefChem:395926268-109-8Boric acid, monoisopropanolamine salt2-Hydroxypropylammonium orthoborate
5 more reported names
Isopropanolamine borateUNII-YK5M7W95MCFWGLAJMZAXEFTA-UHFFFAOYSA-NEINECS 268-109-8Boric acid--1-aminopropan-2-ol (1/1)
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
1
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D conformers
0
Machine-readable structure identifiers
SMILES
B(O)(O)O.CC(CN)O
InChI
InChI=1S/C3H9NO.BH3O3/c1-3(5)2-4;2-1(3)4/h3,5H,2,4H2,1H3;2-4H
InChIKey
FWGLAJMZAXEFTA-UHFFFAOYSA-N

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 68130-12-1
CAS 68130-12-1PubChem CID 82594

Verified chemistry for CAS 68130-12-1

Monoethanolamine borate

IUPAC name
2-aminoethoxyboronic acid
Molecular formula
C2H8BNO3
Molecular weight
104.90 g/mol
Exact mass
105.0597233 Da
Monoisotopic mass
105.0597233 Da
Topological polar surface area
75.7 Ų
Molecular complexity
41.0
Formal charge
0
Hydrogen-bond donors
3
Hydrogen-bond acceptors
4
Rotatable bonds
3
Heavy atoms
7
Covalent units
1

Names and synonyms reported to PubChem

Actracor MMEA-BorateEthanolamine borate (1:1)Ethanol, 2-amino-, monoester with boric acid (H3BO3)Ethanol, 2-amino-, ester with boric acid (H3BO3) (1:1)5I4T660488RefChem:1089826233-829-3
12 more reported names
Ethanolamine borateTrigamine2-Aminoethanol, monoester with boric acidBoric acid, 2-aminoethyl ester2-aminoethyl dihydrogen borateUNII-5I4T660488EINECS 233-829-3EC 233-829-3boric acid-beta-aminoethylesterJCAYXDKNUSEQRT-UHFFFAOYSA-NBC 140Ethanol, 2-amino-, monoester with boric acid
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D conformers
0
Machine-readable structure identifiers
SMILES
B(O)(O)OCCN
InChI
InChI=1S/C2H8BNO3/c4-1-2-7-3(5)6/h5-6H,1-2,4H2
InChIKey
JCAYXDKNUSEQRT-UHFFFAOYSA-N

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Official source and provenance

Registered source
Brazil ANVISA consolidated prohibited substances — RDC 529/2021 through RDC 1.030/2026
Source reference
RDC 529/2021 consolidated annex, entry 1407 (through RDC 1.030/2026)
Source record ID
annex:1407
Source version
RDC 529/2021 consolidated through RDC 1.030/2026
Source language
Portuguese with official English identity where published
Translation status
Official English translation · English translation
Effective date
2026-06-15
Source updated
2026-06-15
Snapshot checked
2026-08-31 15:26 UTC
Validation method
pdfplumber government baseline + 4 RDC 1.030 exclusions + 15 additions; 1,387 substantive rows
SHA-256
a212e85540a186a842664fbdd4f351af0b1b4baeeb0c4765b9b52c6ce91c1e84

Registered dataset notes

Dataset coverage
All 1,387 substantive current prohibited rows after applying RDC 1.030/2026 additions, amendments and exclusions to RDC 529/2021
Authority note
Binding consolidated prohibited list for personal-hygiene products, cosmetics and perfumes
Inspect the exact official sourceRegulator guidance

How this record fits the market dataset

1387
current Brazil records
1387
records marked Prohibited
1387
records from this source version
1335
market records with CAS identity

Status distribution

Prohibited: 1387

Condition text is present on 1387 of 1387 current records. An empty condition field is interpreted according to the record type above; it is never converted into an unrestricted-use claim.

Brazil market context

Complete prohibited dataset plus current restricted-list workflow

Coverage version: ANVISA RDC 1.029/2026 and RDC 1.030/2026, published 15 June 2026

All 1,387 substantive current prohibited rows in RDC 529/2021 consolidated through RDC 1.030/2026, plus the current RDC 1.029 restricted-list and identity workflow.

Verification checklist

  1. Resolve Portuguese, INCI and CAS identity with the ANVISA crosswalk.
  2. Check the consolidated prohibited list including RDC 1.030/2026 changes.
  3. Apply RDC 1.029/2026 restrictions and the still-effective complementary rules.
  4. Verify Mercosur incorporation, regularisation, labelling and transition periods.

Official market sources

Verification workflow and record completeness

Before using this result in a compliance decision

  1. Confirm that “Boratos, tetraboratos, octaboratos e sais e ésteres do ácido bórico, incluindo octaboratos dissódicos, MEA-borate, MIPA-borate, boratos de potássio, zinco e sódio, bórax e borato fenil mercúrico” and every CAS/EC identifier refer to the material in your supplier specification.
  2. Resolve Portuguese, INCI and CAS identity with the ANVISA crosswalk.
  3. Check the consolidated prohibited list including RDC 1.030/2026 changes.
  4. Apply RDC 1.029/2026 restrictions and the still-effective complementary rules.
  5. Verify Mercosur incorporation, regularisation, labelling and transition periods.
  6. Document the source version and recheck the regulator before manufacture, notification or market placement.

Fields available in this record

  • Official substance nameAvailable
  • CASAvailable
  • ECAvailable
  • Separate condition textAvailable
  • Effective dateAvailable
  • Snapshot hash and methodAvailable

Questions this page answers

This official record identifies the substance as prohibited for cosmetic use in the stated market scope. Do not rely on a formulation containing this identity until the cited source, effective date and exact substance match have been verified.

A prohibition entry may contain no separate condition text because the regulatory outcome is the prohibition itself. RDC 1.030/2026 amends rather than replaces the prohibited baseline, and the second restricted-list revision was still under consultation in July 2026.

The record cites RDC 529/2021 consolidated annex, entry 1407 (through RDC 1.030/2026), source version RDC 529/2021 consolidated through RDC 1.030/2026. Open the official source.

No. CAS helps resolve identity, but jurisdictions can classify the same substance differently and can apply different product scopes, limits, warnings and transition dates.

Stable citation

Boratos, tetraboratos, octaboratos e sais e ésteres do ácido bórico, incluindo octaboratos dissódicos, MEA-borate, MIPA-borate, boratos de potássio, zinco e sódio, bórax e borato fenil mercúrico. RDC 529/2021 consolidated annex, entry 1407 (through RDC 1.030/2026). Brazil. Source version RDC 529/2021 consolidated through RDC 1.030/2026. CosIng Checker regulatory record: https://cosingchecker.com/regulations/br/records/14582/

Cite the regulator as the legal authority. This page is a structured evidence index and verification aid, not a substitute for the official text or professional legal assessment.

Interpretation and limits for Brazil

This official record identifies the substance as prohibited for cosmetic use in the stated market scope.

Do not rely on a formulation containing this identity until the cited source, effective date and exact substance match have been verified.

How to interpret the legal role

The cited row forms part of a binding rule or legally incorporated list for this market.

Evidence on this page

  • Recorded outcome: Prohibited
  • Legal role: Binding rule
  • Source version: RDC 529/2021 consolidated through RDC 1.030/2026
  • Effective date: 2026-06-15

What it does not prove

RDC 1.030/2026 amends rather than replaces the prohibited baseline, and the second restricted-list revision was still under consultation in July 2026.

Further authoritative substance research

These sources can add identity, safety, exposure or hazard context. A link is not evidence that the database contains this exact substance, and none of these sources overrides the market decision above.

Cosmetic Ingredient Review safety assessments

Expert Panel conclusions, assessed ingredient groups, use conditions, dates and report documents

Independent expert review considered by FDA; not a government approval or binding market rule

Research this identity at the source

FDA Global Substance Registration System

UNII identifiers, preferred names, substance types, codes and public substance relationships

Identity registry only; UNII availability does not imply FDA review or approval

Research this identity at the source

ILO/WHO International Chemical Safety Cards

Hazards, symptoms, first aid, storage, incompatibilities and physical properties for covered chemicals

International occupational chemical-safety reference; not cosmetic-use approval

Research this identity at the source

Japan NITE-CHRIP

Chemical identity, Japanese and foreign legal lists, GHS hazards and exposure-related information

Chemical-management evidence; cosmetic status remains governed by the applicable MHLW standard and market rules

Research this identity at the source

NIOSH Pocket Guide to Chemical Hazards

REL, PEL, IDLH, properties, exposure routes, symptoms, target organs, first aid and measurement methods for covered workplace chemicals

US occupational-health guidance and limits; not a cosmetic ingredient decision

Research this identity at the source

OECD eChemPortal

Gateway to authority-owned physical-property, fate, ecotoxicity, toxicity, exposure and GHS records

Discovery gateway; each linked authority remains responsible for its data

Research this identity at the source

US EPA CompTox CTX APIs

API key required for import

DTXSID identity, experimental and predicted properties, toxicity, bioactivity, exposure and environmental data

Scientific and computational evidence; predictions must remain labelled and do not determine cosmetic legality

Research this identity at the source