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InventoryRef 3277112/08/2020

CI 45405

Dipotassium 3,6-dichloro-2-(2,4,5,7-tetrabromo-6-oxido-3-oxoxanthen-9-yl)benzoate

CI 45405 is linked to 1 EU annex record on this page. Inventory note: IV/78.

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Regulatory evidence by market

This matrix separates verified ingredient rules from sources that are mapped but not yet imported. No imported rule does not mean the ingredient is permitted.

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MarketEvidence statusRecordsSource language
European UnionEvidence linked
Positive-list entry with conditions
Open this evidence		1English and EU languages
Great BritainSource mapped
Official source mapped; ingredient rule not imported
0English
CanadaSource mapped
Official source mapped; ingredient rule not imported
0English and French
New ZealandEvidence linked
Permitted list with conditions
Open this evidence		1English
ASEANSource mapped
Official source mapped; ingredient rule not imported
0English and national languages
ChinaSource mapped
Official source mapped; ingredient rule not imported
0Chinese with selected English material
JapanSource mapped
Official source mapped; ingredient rule not imported
0Japanese; official English translation available
South KoreaSource mapped
Official source mapped; ingredient rule not imported
0Korean with some English names
United StatesSource mapped
Official source mapped; ingredient rule not imported
0English
AustraliaSource mapped
Official source mapped; ingredient rule not imported
0English
BrazilSource mapped
Official source mapped; ingredient rule not imported
0Portuguese with INCI crosswalks
IndiaSource mapped
Official source mapped; ingredient rule not imported
0English and Hindi
Saudi ArabiaSource mapped
Official source mapped; ingredient rule not imported
0Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 6441-77-6
CAS 6441-77-6PubChem CID 22948

Phloxine

IUPAC name
dipotassium;2',4',5',7'-tetrabromo-4,7-dichloro-3-oxospiro[2-benzofuran-1,9'-xanthene]-3',6'-diolate
Molecular formula
C20H4Br4Cl2K2O5
Molecular weight
793.0 g/mol
Exact mass
791.54024 Da
Topological polar surface area
81.7 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
5
Covalent units
3
Defined stereocentres
0

Also known as

Acid red 98C.I. ACID RED 98CI acid red 98C.I. 45405QDW0T759T6CI 45405Dipotassium 3,6-dichloro-2-(2,4,5,7-tetrabromo-6-oxido-3-oxoxanthen-9-yl)benzoateFluorescein, 4,7-dichloro-2',4',5',7'-tetrabromo-, dipotassium salt
16 more reported names
Spiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one, 2',3',5',7'-tetrabromo-4,7-dichloro-3',6'-dihydroxy-, dipotassium saltSpiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one, 2',4',5',7'-tetrabromo-4,7-dichloro-3',6'-dihydroxy-, potassium salt (1:2)Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 2',4',5',7'-tetrabromo-4,7-dichloro-3',6'-dihydroxy-, potassium salt (1:2)RefChem:1731992',4',5',7'-Tetrabromo-4,7-tetrabromo-4,7-dichloro-3',6'-dihydrox-yspiro(isobenzofuran-1(3H)9'-(9H)xanthen)-3-one, dipotassium salt229-225-4Phloxine KToyo Acid PhloxineCCRIS 9133JBBPTUVOZCXCSU-UHFFFAOYSA-LEINECS 229-225-4PhloxineDISCONTINUEDUNII-QDW0T759T6C.I. FOOD RED 922,4,5,7-Tetrabromo-12,15-dichlorofluorescein, dipotassium salt4,6-Dichloro-2',4',5',7'-tetrabromofluorescein dipotassium salt
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for CI 45405

INCI name

CI 45405

Description

Dipotassium 3,6-dichloro-2-(2,4,5,7-tetrabromo-6-oxido-3-oxoxanthen-9-yl)benzoate

Record provenance

Inventory reference
32771
Imported identity
CI 45405
Source update
12/08/2020
European Commission CosIng source notes
Annex IV Restriction reference
Entry 78

CI 45405

CAS: 6441-77-6
EC: 229-225-4

Key data

CAS
6441-77-6
EC
229-225-4
Restriction
IV/78
Function
COLORANT
Exclusively or mainly intended to colour the cosmetic product, the body as a whole or certain parts thereof, by absorption or reflection of visible light. All authorised colorants are substances in the positive list of Annex IV to the Cosmetics Regulation 1223/2009.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#6416 · CI 45405

Ingredients with overlapping formulation functions

CI 45350COLORANT
CI 45370COLORANT
CI 45380COLORANT
CI 45396COLORANT
CI 45410COLORANT, HAIR DYEING
CI 45425COLORANT
CI 45430COLORANT
CI 47000COLORANT

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicalsPubChem PUG RESTEU Safety Gate cosmetic product alertsECHA CHEMUS EPA CompToxCosmetic Ingredient Review safety assessmentsFDA Global Substance Registration SystemILO/WHO International Chemical Safety CardsJapan NITE-CHRIPNIOSH Pocket Guide to Chemical HazardsOECD eChemPortal

How CI 45405 appears in the CosIng inventory

The CosIng inventory lists CI 45405 as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.

CI 45405 is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

CI 45405 appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

The restriction field for CI 45405 reads: "IV/78". This is the restriction note recorded in the CosIng inventory for this ingredient. For authoritative conditions and limits, always refer to the linked annex entries above.

According to the EU CosIng inventory, CI 45405 carries the following function designation(s):

CAS 6441-77-6 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.
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Source note for CI 45405

This page combines the CosIng inventory entry for CI 45405 with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research CI 45405 and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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