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InventoryRef 3277212/08/2020

CI 45410

3,4,5,6-Tetrachloro-2-(1,4,5,8-tetrabromo-6-hydroxy-3-oxoxanthen-9-yl)benzoic acid

CI 45410 is linked to 2 EU annex records on this page. Inventory note: IV/79 III/270 (Acid Red 9).

Regulatory evidence by market

This matrix separates verified ingredient rules from sources that are mapped but not yet imported. No imported rule does not mean the ingredient is permitted.

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MarketEvidence statusRecordsSource language
European UnionEvidence linked
Restricted entry found
Open this evidence
2English and EU languages
Great BritainSource mapped
Official source mapped; ingredient rule not imported
0English
CanadaSource mapped
Official source mapped; ingredient rule not imported
0English and French
New ZealandSource mapped
Official source mapped; ingredient rule not imported
0English
ASEANSource mapped
Official source mapped; ingredient rule not imported
0English and national languages
ChinaSource mapped
Official source mapped; ingredient rule not imported
0Chinese with selected English material
JapanSource mapped
Official source mapped; ingredient rule not imported
0Japanese; official English translation available
South KoreaSource mapped
Official source mapped; ingredient rule not imported
0Korean with some English names
United StatesSource mapped
Official source mapped; ingredient rule not imported
0English
AustraliaSource mapped
Official source mapped; ingredient rule not imported
0English
BrazilSource mapped
Official source mapped; ingredient rule not imported
0Portuguese with INCI crosswalks
IndiaSource mapped
Official source mapped; ingredient rule not imported
0English and Hindi
Saudi ArabiaSource mapped
Official source mapped; ingredient rule not imported
0Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 13473-26-2
CAS 13473-26-2PubChem CID 83511

D&C Red No. 27

Phloxine O is a xanthene dye that is fluorescein in which the hydrogens at positions 2',4',5' and 7' are replaced by bromo groups, and the hydrogens at positions 4,5,6 and 7 are replaced by chloro groups. It is a red synthetic pigment which is widely used in colored cosmetics (e.g. lipsticks and blushers). It has a role as a fluorescent dye. It is a polyphenol, a tetrachlorobenzene, a dibromobenzene, a gamma-lactone, a xanthene dye, an oxaspiro compound, an organic heteropentacyclic compound and a member of 2-benzofurans. It is functionally related to a fluorescein (lactone form). ChEBI

IUPAC name
2',4',5',7'-tetrabromo-4,5,6,7-tetrachloro-3',6'-dihydroxyspiro[2-benzofuran-3,9'-xanthene]-1-one
Molecular formula
C20H4Br4Cl4O5
Molecular weight
785.7 g/mol
Exact mass
785.54759 Da
XLogP3
8.7
Topological polar surface area
76.0 Ų
Hydrogen-bond donors
2
Hydrogen-bond acceptors
5
Covalent units
1
Defined stereocentres
0

Also known as

D & C Red no. 27Phloxine OAcid Phloxine PBSolvent Red 482',4',5',7'-tetrabromo-4,5,6,7-tetrachlorofluoresceinPhloxine BBN SupraC.I. Solvent Red 48Japan Red 218
16 more reported names
D&C Red 27D&C red no.27TetrachlorotetrabromofluoresceinC,I, Solvent Red 48C.I. 45410AD and C Red No. 27Red No. 218CCRIS 4905CI 45410:1EINECS 236-747-62LRS185U6KTETRACHLOROEOSINCI Solvent Red 48DC RED NO. 27DYE DC RED NO. 27AKA218
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for CI 45410

INCI name

CI 45410

Description

3,4,5,6-Tetrachloro-2-(1,4,5,8-tetrabromo-6-hydroxy-3-oxoxanthen-9-yl)benzoic acid

Record provenance

Inventory reference
32772
Imported identity
CI 45410
Source update
12/08/2020
European Commission CosIng source notes
Annex III Restriction reference
Entry 270

ACID RED 92

CAS: 18472-87-2
EC: 242-355-6
Annex IV Restriction reference
Entry 79

CI 45410

CAS: 18472-87-2
EC: 242-355-6

Key data

CAS
18472-87-2 / 13473-26-2
EC
242-355-6 / 236-747-6
Restriction
IV/79 III/270 (Acid Red 9)
Function
COLORANT
Exclusively or mainly intended to colour the cosmetic product, the body as a whole or certain parts thereof, by absorption or reflection of visible light. All authorised colorants are substances in the positive list of Annex IV to the Cosmetics Regulation 1223/2009.
HAIR DYEING
Imparting color to hair. Hair dyeing preparations may be temporary, semi-permanent, or permanent, depending on the length of time the colorant remains on the hair.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

Ingredients with overlapping formulation functions

Additional official and scientific sources

11 external databases to check this identity in

How CI 45410 appears in the CosIng inventory

The CosIng inventory lists CI 45410 as a cosmetic ingredient and this page links it to 2 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

CI 45410 is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

CI 45410 appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

The restriction field for CI 45410 reads: "IV/79 III/270 (Acid Red 9)". This is the restriction note recorded in the CosIng inventory for this ingredient. For authoritative conditions and limits, always refer to the linked annex entries above.

According to the EU CosIng inventory, CI 45410 carries the following function designation(s):

CAS 18472-87-2 / 13473-26-2 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

Source note for CI 45410

This page combines the CosIng inventory entry for CI 45410 with 2 linked Annex II–VI records from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research CI 45410 and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

Tools & next steps

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