CosIng Checker
CosIng Checker
EU cosmetic ingredients, restrictions and safety
Login
Annex V Entry 21 02/08/2021

2-BROMO-2-NITROPROPANE-1,3-DIOL

Bronopol

2-BROMO-2-NITROPROPANE-1,3-DIOL appears in Annex V as a positive-list preservative entry for EU cosmetics. Maximum concentration in this record: 0.1%.

Search similar Back to annex Compare
Permitted preservative— Annex V, EU Regulation 1223/2009
Max conc.: 0.1%
Entry: 21

Record details

Maximum concentration

0.1%

Other restrictions

Avoid formation of nitrosamines

INCI glossary name

2-BROMO-2-NITROPROPANE-1,3-DIOL

Chemical name

Bronopol

Chemical / IUPAC name

2-Bromo-2-nitropropane-1,3-diol

Regulatory information

Regulation

(EC) 2009/1223

SCCS opinions

Identified ingredients

Key data

CAS
52-51-7
EC
200-143-0
Annex
V
Entry number
21

Inventory links for 2-BROMO-2-NITROPROPANE-1,3-DIOL

Direct matches are limited for this record, so nearby entries from Annex V are shown as well.

Annex V 19
Nearby record in the same annex

Hexetidine

CAS: 141-94-6
EC: 205-513-5
Annex V 23
Nearby record in the same annex

Triclocarban

CAS: 101-20-2
EC: 202-924-1
Annex V 25
Nearby record in the same annex

Triclosan

CAS: 3380-34-5
EC: 222-182-2
Annex V 16
Nearby record in the same annex

THIMEROSAL

CAS: 54-64-8
EC: 200-210-4
Annex V 26
Nearby record in the same annex

CHLOROXYLENOL

CAS: 88-04-0 / 1321-23-9
EC: 201-793-8 / 215-316-6

What Annex V means for 2-BROMO-2-NITROPROPANE-1,3-DIOL

2-BROMO-2-NITROPROPANE-1,3-DIOL is an approved preservative listed in Annex V of EU Cosmetics Regulation 1223/2009. Only substances on this positive list may be used as cosmetic preservatives in the EU.

Each preservative entry specifies maximum permitted concentrations and applicable product scope. Concentrations must not exceed the listed maximum. Some preservatives require warning statements on the product label.

This record is linked to 1 CosIng inventory ingredient for name and identifier cross-reference. The page also surfaces 12 related annex records with overlapping identifiers, annex logic or naming patterns.

Compliance checklist

  • Use concentration must not exceed: 0.1%
  • Verify the preservative is effective at the permitted concentration for your matrix.

Frequently asked questions

Yes. 2-BROMO-2-NITROPROPANE-1,3-DIOL is listed in Annex V of EU Cosmetics Regulation 1223/2009 as a permitted preservative. It may be used in cosmetics up to the maximum concentration specified above, within the permitted product scope.

CAS 52-51-7 is the unique numerical identifier assigned to 2-BROMO-2-NITROPROPANE-1,3-DIOL by the Chemical Abstracts Service. In cosmetic compliance work, the CAS number is used to cross-reference the substance across regulatory databases, raw material specifications and safety assessment reports. Multiple EU annex entries may share the same CAS number if the same substance appears under different conditions or in different annexes.

The maximum concentration of 0.1% applies to the concentration of the substance in the ready-to-use cosmetic product. When the substance is supplied as part of a blend or mixture, the calculation must account for the contribution of all sources in the formulation. The combined concentration must not exceed the stated limit.

Use the INCI Checker tool on this site to paste your full ingredient list (INCI) and scan it against all Annex II–VI entries. The tool highlights any ingredients that match restricted, prohibited or allergen-flagged records. This is useful for rapid compliance screening of finished product formulas or raw material declarations.
Open INCI Checker

Source note for Annex V record 2-BROMO-2-NITROPROPANE-1,3-DIOL

This page summarizes one Annex V record for 2-BROMO-2-NITROPROPANE-1,3-DIOL from public European Commission cosmetic materials and adds linked inventory or identifier matches when available.

Use this record page to review Annex V conditions for 2-BROMO-2-NITROPROPANE-1,3-DIOL, but confirm any final regulatory decision against the current official annex wording and source files.

View sourcesView updates

Tools & next steps

Check your formula

Paste a full INCI list to detect 2-BROMO-2-NITROPROPANE-1,3-DIOL and other flagged EU annex records in one pass.

INCI Checker

Compare entries

Compare 2-BROMO-2-NITROPROPANE-1,3-DIOL side by side with another annex record to review differences in restrictions, concentrations and annex placement.

Compare

Browse the annex

See all records in Annex V and compare regulatory conditions across substances in this annex.

Open Annex V