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Annex IV Entry 75 14/08/2020

4',5'-Dibromo-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3-one and its insoluble barium, strontium and zirconium lakes, salts and pigments

CI 45370

4',5'-Dibromo-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3-one and its insoluble barium, strontium and zirconium lakes, salts and pigments appears in Annex IV as a positive-list colorant entry for EU cosmetics.

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Permitted colorant— Annex IV, EU Regulation 1223/2009
Entry: 75

Record details

Warnings

Not more than 1% 2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid and 2% 2-(bromo-6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid

Colour index or glossary

CI 45370

Chemical name

4',5'-Dibromo-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3-one and its insoluble barium, strontium and zirconium lakes, salts and pigments

Chemical / IUPAC name

4',5'-Dibromo-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3-one and its insoluble barium, strontium and zirconium lakes, salts and pigments

Color

Orange

Regulatory information

Regulation

(EC) 2009/1223

Identified ingredients

Key data

CAS
596-03-2; 4372-02-5
EC
209-876-0; 224-468-2
Annex
IV
Entry number
75

Inventory links for 4',5'-Dibromo-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3-one and its insoluble barium, strontium and zirconium lakes, salts and pigments

Inventory Restriction reference
Ref 32768

CI 45370

CAS: 4372-02-5 / 596-03-2
EC: 224-468-2 / 209-876-0
Inventory Identified ingredient
Ref 78541

SOLVENT RED 72

CAS: 596-03-2 / 4372-02-5
EC: 209-876-0 / 224-468-2

Direct matches are limited for this record, so nearby entries from Annex IV are shown as well.

Annex IV 74
Nearby record in the same annex

CI 45350

CAS: 518-45-6; 518-47-8
EC: -; 208-253-0
Annex IV 76
Nearby record in the same annex

CI 45380 / ACID RED 87

CAS: 17372-87-1 / 548-26-5 / 15876-39-8 / 15086-94-9 / 94021-89-3
EC: 241-409-6 / - / 240-005-7 / 239-138-3 / 301-481-2
Annex IV 73
Nearby record in the same annex

CI 45220

CAS: 5873-16-5
EC: 227-528-6
Annex IV 77
Nearby record in the same annex

CI 45396

CAS: 24545-86-6
EC: 246-308-0
Annex IV 78
Nearby record in the same annex

CI 45405

CAS: 6441-77-6
EC: 229-225-4
Annex IV 79
Nearby record in the same annex

CI 45410

CAS: 18472-87-2
EC: 242-355-6
Annex IV 70
Nearby record in the same annex

CI 44090

CAS: 3087-16-9
EC: 221-409-2
Annex IV 80
Nearby record in the same annex

CI 45430

CAS: 12227-78-0
EC: 240-474-8
Annex IV 69
Nearby record in the same annex

CI 44045

CAS: 2580-56-5
EC: 219-943-6

What Annex IV means for 4',5'-Dibromo-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3-one and its insoluble barium, strontium and zirconium lakes, salts and pigments

4',5'-Dibromo-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3-one and its insoluble barium, strontium and zirconium lakes, salts and pigments is an approved colorant listed in Annex IV of EU Cosmetics Regulation 1223/2009. Only colorants on this positive list may be used to colour cosmetic products on the EU market.

Some colorants in Annex IV are restricted by product type — for example, prohibited from use around the eyes or in products applied to mucous membranes. Check the product type and conditions fields above before use.

This record is linked to 2 CosIng inventory ingredients for name and identifier cross-reference. The page also surfaces 12 related annex records with overlapping identifiers, annex logic or naming patterns.

Compliance checklist

  • Confirm colorant is used only in permitted product types listed above.
  • Record the Colour Index number and CAS identifier in the ingredient declaration.

Frequently asked questions

Yes. 4',5'-Dibromo-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3-one and its insoluble barium, strontium and zirconium lakes, salts and pigments is included in Annex IV of EU Cosmetics Regulation 1223/2009 as a permitted colorant. Only colorants on this positive list may be used to colour cosmetic products in the EU. Check the product type conditions above for any use restrictions.

CAS 596-03-2; 4372-02-5 is the unique numerical identifier assigned to 4',5'-Dibromo-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3-one and its insoluble barium, strontium and zirconium lakes, salts and pigments by the Chemical Abstracts Service. In cosmetic compliance work, the CAS number is used to cross-reference the substance across regulatory databases, raw material specifications and safety assessment reports. Multiple EU annex entries may share the same CAS number if the same substance appears under different conditions or in different annexes.

Use the INCI Checker tool on this site to paste your full ingredient list (INCI) and scan it against all Annex II–VI entries. The tool highlights any ingredients that match restricted, prohibited or allergen-flagged records. This is useful for rapid compliance screening of finished product formulas or raw material declarations.
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Source note for Annex IV record 4',5'-Dibromo-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3-one and its insoluble barium, strontium and zirconium lakes, salts and pigments

This page summarizes one Annex IV record for 4',5'-Dibromo-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3-one and its insoluble barium, strontium and zirconium lakes, salts and pigments from public European Commission cosmetic materials and adds linked inventory or identifier matches when available.

Use this record page to review Annex IV conditions for 4',5'-Dibromo-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3-one and its insoluble barium, strontium and zirconium lakes, salts and pigments, but confirm any final regulatory decision against the current official annex wording and source files.

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