HEXYL CINNAMAL
2-Benzylideneoctanal
HEXYL CINNAMAL is listed in Annex III and may only be used under the conditions shown in this record.
This substance is on the EU list of fragrance allergens that must be named individually in the ingredient list, rather than being covered by the word "parfum", once it exceeds 0.001% in a leave-on product or 0.01% in a rinse-off product.
Declaration is a labelling duty under Article 19, not a restriction on use. See the allergen record
Chemical identity and properties
alpha-Hexylcinnamaldehyde
Alpha-hexylcinnamaldehyde is a member of the class of cinnamaldehydes carrying a hexyl substituent at the alpha-position. It is functionally related to an (E)-cinnamaldehyde. — ChEBI
- IUPAC name
- (2E)-2-benzylideneoctanal
- Molecular formula
- C15H20O
- Molecular weight
- 216.32 g/mol
- Exact mass
- 216.151415257 Da
- XLogP3
- 4.8
- Topological polar surface area
- 17.1 Ų
- Hydrogen-bond donors
- 0
- Hydrogen-bond acceptors
- 1
- Covalent units
- 1
- Defined stereocentres
- 0
Also known as
16 more reported names
External database identifiers
- ChEBI:CHEBI:55365
- ChEMBL:CHEMBL1449245
- EPA DTXSID:DTXSID401020801
- PubMed:31734321
- PubMed:26244607
- PubMed:22381623
- PubMed:21920952
Evidence from additional scientific databases
EMBL-EBI ChEBI
α-hexylcinnamaldehyde
A member of the class of cinnamaldehydes carrying a hexyl substituent at the α-position.
- Formula
- C15H20O
- Average mass
- 216.324 g/mol
- Monoisotopic mass
- 216.15142 Da
- Formal charge
- 0
- cinnamaldehydes — is a (CHEBI:23245)
- (E)-cinnamaldehyde — has functional parent (CHEBI:16731)
- cinnamaldehydes — is a (CHEBI:23245)
Additional curated names
Cross-references from this source
- CAS: 101-86-0 — ChemIDplus
- CAS: 101-86-0 — NIST Chemistry WebBook
- REGISTRY_NUMBER: 2502968 — Reaxys
- MANUAL_X_REF: HMDB0031736 — HMDB
- MANUAL_X_REF: US5792467 — Patent
Mapped by: Exact CAS cross-reference in the ChEBI compound record. Source updated: 2015-10-23. Retrieved: 2026-08-31. Open source record
NIH PubChem PUG-View
Attributed physical-property, hazard, environmental and use annotations.
- Boiling Point: 174-175 °C (15 mm Hg) Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
- Density: 0.950-0.961 Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
- Melting Point: 4 °C Source: Human Metabolome Database (HMDB)
- Physical Description: Other Solid; CBI; Liquid; Dry Powder; Liquid Source: EPA Chemical Data Reporting (CDR)
- Physical Description: Liquid Source: Human Metabolome Database (HMDB)
- Physical Description: Pale yellow liquid, jasmine like odour Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
- Refractive Index: 1.547-1.553 Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
- Solubility: insoluble in water; miscible in oils Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
- Solubility: miscible (in ethanol) Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
- Note: This chemical does not meet GHS hazard criteria for < 0.1% (2 of 2496) of reports. Source: European Chemicals Agency (ECHA)
- Signal: Warning Source: European Chemicals Agency (ECHA)
- GHS Hazard Statements: H317 (99.6%): May cause an allergic skin reaction [Warning Sensitization, Skin]; H400 (65.1%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]; H411 (62.4%): Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard] Source: European Chemicals Agency (ECHA)
- Precautionary Statement Codes: P261, P272, P273, P280, P302+P352, P321, P333+P317, P362+P364, P391, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
- ECHA C&L Notifications Summary: Aggregated GHS information provided per 2496 reports by companies from 37 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Reported as not meeting GHS hazard criteria per 2 of 2496 reports by companies.; There are 36 notifications provided by 2494 of 2496 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
- GHS Hazard Statements: H317 (100%): May cause an allergic skin reaction [Warning Sensitization, Skin]; H400 (100%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]; H411 (99.4%): Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard] Source: European Chemicals Agency (ECHA)
- ECHA C&L Notifications Summary: Aggregated GHS information provided per 168 reports by companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
- Signal: Warning Source: NITE-CMC
- GHS Hazard Statements: H315: Causes skin irritation [Warning Skin corrosion/irritation]; H317: May cause an allergic skin reaction [Warning Sensitization, Skin] Source: NITE-CMC
- Precautionary Statement Codes: P261, P264, P272, P280, P302+P352, P321, P332+P317, P333+P317, P362+P364, and P501 (click each P-code to see the statement) Source: NITE-CMC
- Signal: Warning Source: Hazardous Chemical Information System (HCIS), Safe Work Australia
- GHS Hazard Statements: H315: Causes skin irritation [Warning Skin corrosion/irritation]; H317: May cause an allergic skin reaction [Warning Sensitization, Skin] Source: Hazardous Chemical Information System (HCIS), Safe Work Australia
- Consumer Uses: Fragrance Source: EPA Chemical Data Reporting (CDR)
- Industry Uses: Fragrance; Flavoring and nutrient Source: EPA Chemical Data Reporting (CDR)
Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record
Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.
Additional source coverage and match status
| Source | Result | Checked |
|---|---|---|
| EMBL-EBI ChEBI | Exact match | 2026-08-31 |
| NIH PubChem PUG-View | Exact match | 2026-08-31 |
A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
Record details
Other restrictions
The presence of the substance must be indicated in the list of ingredients referred to in Article 19(1)g when its concentration exceeds:
- 0.001% in leave-on products
- 0.01% in rinse-off products
INCI glossary name
HEXYL CINNAMAL
Chemical name
2-Benzylideneoctanal
Regulatory information
SCCS opinions
- Opinion concerning Essential Oils
- Opinion concerning Fragrance Allergy in Consumers - A Review of the Problem - Analysis of the need for appropriate Consumer Information and Identification of Consumer Allergens
- Opinion concerning the Interim Position on Fragrance Allergy
- Memorandum on the SCCNFP Opinion concerning Fragrance Allergy
Identified ingredients
EU Fragrance Allergen
This substance is linked to an EU fragrance-allergen reference. Check the current Annex III entry for the declaration threshold and any additional conditions.
Key data
Inventory links for HEXYL CINNAMAL
Related records for HEXYL CINNAMAL
Direct matches are limited for this record, so nearby entries from Annex III are shown as well.
Citronellol
Limonene
EVERNIA FURFURACEA EXTRACT
What Annex III means for HEXYL CINNAMAL
HEXYL CINNAMAL is a restricted substance under Annex III of EU Cosmetics Regulation 1223/2009. Its use in cosmetics is only permitted under the specific conditions set out in the entry above, including applicable concentration limits, product type restrictions and required warning statements.
When including this substance in a formulation, all conditions — maximum concentration, product scope and warning labels — must be met simultaneously. Compliance with one condition does not override the others.
This record is linked to 1 CosIng inventory ingredient for name and identifier cross-reference. The page also surfaces 12 related annex records with overlapping identifiers, annex logic or naming patterns.
Compliance checklist
- Document conditions of use in the Product Information File (PIF).
- This substance is a regulated fragrance allergen. Declare it on the label by INCI name above 0.001% in leave-on or 0.01% in rinse-off products.
Frequently asked questions
Source note for Annex III record HEXYL CINNAMAL
This page summarizes one Annex III record for HEXYL CINNAMAL from public European Commission cosmetic materials and adds linked inventory or identifier matches when available.
Use this record page to review Annex III conditions for HEXYL CINNAMAL, but confirm any final regulatory decision against the current official annex wording and source files.
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