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Permitted list with conditionsBinding ruleASEANOriginal is EnglishOfficial-source import checked

Alkyl (C ) trimethyl ammonium bromide and 12-22 chloride) (+) Behentrimonium chloride (11) (CAS No. 17301- 53-0), cetrimonium bromide (CAS No. 57-09-0), cetrimonium chloride (12) (CAS No. 112-02- 7), laurtrimonium bromide, (CAS No. 1119- 94-4), laurtrimonium chloride (CAS No. 112- 00-5), steartrimonium bromide (CAS No. 1120-02-1), steartrimonium chloride (12) (CAS No. 112-03-8)

Alkyl (C ) trimethyl ammonium bromide and 12-22 chloride) (+) Behentrimonium chloride (11) (CAS No. 17301- 53-0), cetrimonium bromide (CAS No. 57-09-0), cetrimonium chloride (12) (CAS No. 112-02- 7), laurtrimonium bromide, (CAS No. 1119- 94-4), laurtrimon

ASEAN Annex VI lists this record among preservatives allowed for cosmetic use. Member-state transition rules and deviations still require local verification.

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Regulatory decision and full conditions

Status
Permitted list with conditions
Legal role
Binding rule
Regulatory summary
ASEAN Annex VI lists this record among preservatives allowed for cosmetic use. Member-state transition rules and deviations still require local verification.
Conditions and restrictions
0.1%

Substance identity

Official source name
Alkyl (C ) trimethyl ammonium bromide and 12-22 chloride) (+) Behentrimonium chloride (11) (CAS No. 17301- 53-0), cetrimonium bromide (CAS No. 57-09-0), cetrimonium chloride (12) (CAS No. 112-02- 7), laurtrimonium bromide, (CAS No. 1119- 94-4), laurtrimonium chloride (CAS No. 112- 00-5), steartrimonium bromide (CAS No. 1120-02-1), steartrimonium chloride (12) (CAS No. 112-03-8)
CAS
17301-53-0; 57-09-0; 112-02-7; 1119-94-4; 112-00-5; 1120-02-1; 112-03-8
EC
241-327-0
Identity mapping
cas_number
Linked ingredient
BEHENTRIMONIUM CHLORIDE
Search this identity across the siteCAS 17301-53-0CAS 57-09-0CAS 112-02-7CAS 1119-94-4CAS 112-00-5CAS 1120-02-1CAS 112-03-8EC 241-327-0

Linked CosIng identity data

Names and aliases

BEHENTRIMONIUM CHLORIDE

CosIng description: Docosyltrimethylammonium chloride

EU inventory restriction note: V/44

Recorded cosmetic function: ANTISTATIC, HAIR CONDITIONING, PRESERVATIVE

Function pages:ANTISTATIC, HAIR CONDITIONING, PRESERVATIVE

View the complete ingredient profile

Cross-market snapshot for this identity

Exact linked records currently present in this site. An absent market means no imported exact match, not permission to use the substance.

7 market datasets

Great Britain

Permitted list with conditionsRestricted

3 linked records · 3 with specific conditions

Open supporting record

New Zealand

Permitted list with conditionsRestricted

10 linked records · 10 with specific conditions

Open supporting record

ASEAN

Current record
Permitted list with conditionsRestricted

3 linked records · 3 with specific conditions

Open supporting record
PubChem 2D chemical structure for CAS 1119-94-4
CAS 1119-94-4PubChem CID 14249

Verified chemistry for CAS 1119-94-4

Dodecyltrimethylammonium bromide

Dodecyltrimethylammonium bromide is a bromide salt and a quaternary ammonium salt. It has a role as a surfactant. It contains a dodecyltrimethylammonium ion. — ChEBI

IUPAC name
dodecyl(trimethyl)azanium bromide
Molecular formula
C15H34BrN
Molecular weight
308.34 g/mol
Exact mass
307.18746 Da
Monoisotopic mass
307.18746 Da
Topological polar surface area
0.0 Ų
Molecular complexity
135.0
Formal charge
0
Hydrogen-bond donors
0
Hydrogen-bond acceptors
1
Rotatable bonds
11
Heavy atoms
17
Covalent units
2

Names and synonyms reported to PubChem

DctabDTABLaurtrimonium bromideLauryltrimethylammonium bromideLTABMorpan DDTAB (surfactant)1-Dodecanaminium, N,N,N-trimethyl-, bromide
16 more reported names
Trimethyllaurylammonium bromideTrimethyldodecylammonium bromideFSM 23N-Lauryl-N,N,N-trimethylammonium bromideN,N,N-Trimethyldodecan-1-ammonium bromideN,N,N-Trimethyl-1-dodecanaminiuim bromideLauryltrimethylaminium bromide6IC8NZ97S2CHEBI:282662ammonium, dodecyltrimethyl-,bromideRefChem:920574214-290-3N,N,N-trimethyldodecan-1-aminium bromideDODECYL TRIMETHYL AMMONIUM BROMIDEdodecyl(trimethyl)azanium;bromideDodecyltrimethylammonium (bromide)
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D conformers
0
Machine-readable structure identifiers
SMILES
CCCCCCCCCCCC[N+](C)(C)C.[Br-]
InChI
InChI=1S/C15H34N.BrH/c1-5-6-7-8-9-10-11-12-13-14-15-16(2,3)4;/h5-15H2,1-4H3;1H/q+1;/p-1
InChIKey
XJWSAJYUBXQQDR-UHFFFAOYSA-M

Evidence from additional scientific databases

NIH PubChem PUG-View
Exact identifier match14249

Attributed physical-property, hazard, environmental and use annotations.

  • Note: This chemical does not meet GHS hazard criteria for 2.2% (2 of 89) of reports. Source: European Chemicals Agency (ECHA)
  • Signal: Danger Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H301 (20.2%): Toxic if swallowed [Danger Acute toxicity, oral]; H302 (53.9%): Harmful if swallowed [Warning Acute toxicity, oral]; H315 (96.6%): Causes skin irritation [Warning Skin corrosion/irritation]; H317 (23.6%): May cause an allergic skin reaction [Warning Sensitization, Skin]; H319 (96.6%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H335 (62.9%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]; H400 (69.7%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]; H410 (66.3%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P261, P264, P264+P265, P270, P271, P272, P273, P280, P301+P316, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P333+P317, P337+P317, P362+P364, P391, P403+P233, P405, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 89 reports by companies from 18 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Reported as not meeting GHS hazard criteria per 2 of 89 reports by companies.; There are 17 notifications provided by 87 of 89 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • Signal: Danger Source: NITE-CMC
  • GHS Hazard Statements: H301: Toxic if swallowed [Danger Acute toxicity, oral]; H315: Causes skin irritation [Warning Skin corrosion/irritation]; H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]; H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] Source: NITE-CMC
  • Precautionary Statement Codes: P264, P270, P273, P280, P301+P316, P302+P352, P321, P330, P332+P317, P362+P364, P391, P405, and P501 (click each P-code to see the statement) Source: NITE-CMC
  • Signal: Danger Source: Hazardous Chemical Information System (HCIS), Safe Work Australia
  • GHS Hazard Statements: H302: Harmful if swallowed [Warning Acute toxicity, oral]; H312: Harmful in contact with skin [Warning Acute toxicity, dermal]; H314: Causes severe skin burns and eye damage [Danger Skin corrosion/irritation] Source: Hazardous Chemical Information System (HCIS), Safe Work Australia
  • Precautionary Statement Codes: P260, P264, P270, P280, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P321, P330, P362+P364, P363, P405, and P501 (click each P-code to see the statement) Source: Hazardous Chemical Information System (HCIS), Safe Work Australia
  • Cosmetic Ingredient Review Conclusion: The CIR Expert Panel concluded the following ingredients are safe in the present practices of use and concentration described in the safety assessment when formulated to be non-irritating...Laurtrimonium Bromide... Source: Cosmetic Ingredient Review (CIR)
  • Cosmetic Ingredient Review Finding(s): Safe for use in cosmetics, with qualifications Source: Cosmetic Ingredient Review (CIR)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 112-00-5
CAS 112-00-5PubChem CID 8152

Verified chemistry for CAS 112-00-5

Dodecyltrimethylammonium chloride

IUPAC name
dodecyl(trimethyl)azanium chloride
Molecular formula
C15H34ClN
Molecular weight
263.89 g/mol
Exact mass
263.2379778 Da
Monoisotopic mass
263.2379778 Da
Topological polar surface area
0.0 Ų
Molecular complexity
135.0
Formal charge
0
Hydrogen-bond donors
0
Hydrogen-bond acceptors
1
Rotatable bonds
11
Heavy atoms
17
Covalent units
2

Names and synonyms reported to PubChem

DODECYL TRIMETHYL AMMONIUM CHLORIDEDTACAlicopLauryltrimethylammonium chlorideLaurtrimonium chlorideCation BBAliquat 4Dehyquart LT
16 more reported names
Cation FBNissan Cation BBn-Dodecyltrimethylammonium chlorideArquad 12Arquad 12DTrimethyllaurylammonium chlorideCatiogen LNissan Cation FBQuartamin 24PQuartamin 24WArquad 12/50Redicote E 5Rewoquat B 18Radiaquat 6465Trimethyldodecylammonium chlorideCatinal LTC 35A
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D conformers
0
Machine-readable structure identifiers
SMILES
CCCCCCCCCCCC[N+](C)(C)C.[Cl-]
InChI
InChI=1S/C15H34N.ClH/c1-5-6-7-8-9-10-11-12-13-14-15-16(2,3)4;/h5-15H2,1-4H3;1H/q+1;/p-1
InChIKey
DDXLVDQZPFLQMZ-UHFFFAOYSA-M

Evidence from additional scientific databases

NIH PubChem PUG-View
Exact identifier match8152

Attributed physical-property, hazard, environmental and use annotations.

  • Note: This chemical does not meet GHS hazard criteria for 2.5% (12 of 476) of reports. Source: European Chemicals Agency (ECHA)
  • Signal: Danger Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H302 (87.2%): Harmful if swallowed [Warning Acute toxicity, oral]; H314 (31.1%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]; H315 (64.1%): Causes skin irritation [Warning Skin corrosion/irritation]; H318 (28.8%): Causes serious eye damage [Danger Serious eye damage/eye irritation]; H319 (54%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H335 (30%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]; H400 (80.3%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]; H410 (27.9%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]; H411 (10.1%): Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P260, P261, P264, P264+P265, P270, P271, P273, P280, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P351+P338, P305+P354+P338, P316, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P363, P391, P403+P233, P405, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 476 reports by companies from 28 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Reported as not meeting GHS hazard criteria per 12 of 476 reports by companies.; There are 27 notifications provided by 464 of 476 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • Signal: Warning Source: NITE-CMC
  • GHS Hazard Statements: H302: Harmful if swallowed [Warning Acute toxicity, oral]; H315: Causes skin irritation [Warning Skin corrosion/irritation]; H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation] Source: NITE-CMC
  • Precautionary Statement Codes: P264, P264+P265, P270, P280, P301+P317, P302+P352, P305+P351+P338, P321, P330, P332+P317, P337+P317, P362+P364, and P501 (click each P-code to see the statement) Source: NITE-CMC
  • GHS Hazard Statements: Not Classified Source: NITE-CMC
  • Signal: Danger Source: Hazardous Chemical Information System (HCIS), Safe Work Australia
  • GHS Hazard Statements: H302: Harmful if swallowed [Warning Acute toxicity, oral]; H312: Harmful in contact with skin [Warning Acute toxicity, dermal]; H314: Causes severe skin burns and eye damage [Danger Skin corrosion/irritation] Source: Hazardous Chemical Information System (HCIS), Safe Work Australia
  • Precautionary Statement Codes: P260, P264, P270, P280, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P321, P330, P362+P364, P363, P405, and P501 (click each P-code to see the statement) Source: Hazardous Chemical Information System (HCIS), Safe Work Australia
  • Cosmetic Ingredient Review Conclusion: The CIR Expert Panel concluded the following ingredients are safe in the present practices of use and concentration described in the safety assessment when formulated to be non-irritating...Laurtrimonium Chloride... Source: Cosmetic Ingredient Review (CIR)
  • Cosmetic Ingredient Review Finding(s): Safe for use in cosmetics, with qualifications Source: Cosmetic Ingredient Review (CIR)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 112-02-7
CAS 112-02-7PubChem CID 8154

Verified chemistry for CAS 112-02-7

Hexadecyltrimethylammonium chloride

Cetyltrimethylammonium chloride is the organic chloride salt of cetyltrimethylammonium. It has a role as a surfactant. It is a quaternary ammonium salt and an organic chloride salt. It contains a cetyltrimethylammonium ion. — ChEBI

IUPAC name
hexadecyl(trimethyl)azanium chloride
Molecular formula
C19H42ClN
Molecular weight
320.0 g/mol
Exact mass
319.3005780 Da
Monoisotopic mass
319.3005780 Da
Topological polar surface area
0.0 Ų
Molecular complexity
181.0
Formal charge
0
Hydrogen-bond donors
0
Hydrogen-bond acceptors
1
Rotatable bonds
15
Heavy atoms
21
Covalent units
2

Names and synonyms reported to PubChem

Cetrimonium chlorideN-Hexadecyltrimethylammonium chlorideDehyquart AGenamin CTACAliquat 6Cetyl trimethyl ammonium chlorideCETACHTAC
16 more reported names
Adogen 444Surfroyal CTACMorpan CHAQuartamin 60WTrimethylcetylammonium chlorideArquad 16-29Arquad 16-50Ammonyx Cetac 30TRIMETHYLHEXADECYLAMMONIUM CHLORIDEIntexsan CTC 29Intexsan CTC 50Arquad 16Barquat CT 29Intexan CTC 29Palmityltrimethylammonium chlorideVariquat E 228
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D conformers
0
Machine-readable structure identifiers
SMILES
CCCCCCCCCCCCCCCC[N+](C)(C)C.[Cl-]
InChI
InChI=1S/C19H42N.ClH/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(2,3)4;/h5-19H2,1-4H3;1H/q+1;/p-1
InChIKey
WOWHHFRSBJGXCM-UHFFFAOYSA-M

Evidence from additional scientific databases

NIH PubChem PUG-View
Exact identifier match8154

Attributed physical-property, hazard, environmental and use annotations.

  • Boiling Point: 180 °F at 760 mmHg (isopropyl alcohol) (USCG, 1999) Source: CAMEO Chemicals
  • Density: 0.9 at 77 °F (approx.) (USCG, 1999) - Less dense than water; will float Source: CAMEO Chemicals
  • First Aid: INGESTION: do NOT induce vomiting; drink large quanities of fluid and call a physician immediately.; EYES: flush with water for at least 15 min. and call a physician.; SKIN: flush with water. (USCG, 1999) Source: CAMEO Chemicals
  • Note: This chemical does not meet GHS hazard criteria for 0.5% (5 of 1105) of reports. Source: European Chemicals Agency (ECHA)
  • Signal: Danger Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H302 (49%): Harmful if swallowed [Warning Acute toxicity, oral]; H311 (28.6%): Toxic in contact with skin [Danger Acute toxicity, dermal]; H314 (41.5%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]; H315 (52.3%): Causes skin irritation [Warning Skin corrosion/irritation]; H318 (85.7%): Causes serious eye damage [Danger Serious eye damage/eye irritation]; H335 (44.3%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]; H400 (99.4%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]; H410 (40.9%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P260, P261, P262, P264, P264+P265, P270, P271, P273, P280, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P319, P321, P330, P332+P317, P361+P364, P362+P364, P363, P391, P403+P233, P405, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 1105 reports by companies from 42 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Reported as not meeting GHS hazard criteria per 5 of 1105 reports by companies.; There are 41 notifications provided by 1100 of 1105 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • Signal: Danger Source: NITE-CMC
  • GHS Hazard Statements: H302: Harmful if swallowed [Warning Acute toxicity, oral]; H315: Causes skin irritation [Warning Skin corrosion/irritation]; H318: Causes serious eye damage [Danger Serious eye damage/eye irritation]; H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]; H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]; H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] Source: NITE-CMC
  • Precautionary Statement Codes: P261, P264, P264+P265, P270, P271, P273, P280, P301+P317, P302+P352, P304+P340, P305+P354+P338, P317, P319, P321, P330, P332+P317, P362+P364, P391, P403+P233, P405, and P501 (click each P-code to see the statement) Source: NITE-CMC
  • Signal: Warning Source: NITE-CMC
  • GHS Hazard Statements: H302: Harmful if swallowed [Warning Acute toxicity, oral]; H315: Causes skin irritation [Warning Skin corrosion/irritation]; H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation] Source: NITE-CMC
  • Precautionary Statement Codes: P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement) Source: NITE-CMC
  • Signal: Danger Source: Hazardous Chemical Information System (HCIS), Safe Work Australia
  • Cosmetic Ingredient Review Conclusion: The CIR Expert Panel concluded the following ingredients are safe in the present practices of use and concentration described in the safety assessment when formulated to be non-irritating...Cetrimonium Chloride... Source: Cosmetic Ingredient Review (CIR)
  • Cosmetic Ingredient Review Finding(s): Safe for use in cosmetics, with qualifications Source: Cosmetic Ingredient Review (CIR)
  • Environmental Bioconcentration: An estimated BCF of 71 was calculated for trimethylhexadecylammonium chloride(SRC), using an estimated log Kow of 3.23(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is moderate. Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 2.2X10+5(SRC), determined from a structure estimation method(2), indicates that trimethylhexadecylammonium chloride is expected to be immobile in soil(SRC). Volatilization of trimethylhexadecylammonium chloride from moist soil surfaces is not expected to be an important fate process(SRC) given an estimated Henry's Law constant of 2.9X10-10 atm-cu m/mole(SRC), using a fragment constant estimation method(3). Trimethylhexadecylammonium chloride is not expected to volatilize from dry soil surfaces(SRC) based upon an estimated vapor pressure of 2.8X10-10 mm Hg(SRC), determined from a fragment constant method(4). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 2.2X10+5(SRC), determined from an estimation method(2), indicates that trimethylhexadecylammonium chloride is expected to adsorb to suspended solids and sediment in water(SRC). Volatilization from water surfaces is not expected(3) based upon an estimated Henry's Law constant of 2.9X10-10 atm-cu m/mole(SRC), developed using a fragment constant estimation method(4). According to a classification scheme(5), an estimated BCF of 71(SRC), from its log Kow of 3.23(6) and a regression-derived equation(7), suggests the potential for bioconcentration in aquatic organisms is moderate. The MITI, closed bottle, and Sturm tests revealed no degradation after 10 days, microbial growth after 17 days, and 84% degradation after 13 days, respectively(8). 10-20 ppm trimethylhexadecylammonium chloride was degraded with a half-life of 3.1 days in freshwater collected from the Ohio river 1 mile below discharge from a municipal treatment plant at 20 °C and pH 6.9(9). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), trimethylhexadecylammonium chloride, which has an estimated vapor pressure of 2.8X10-10 mm Hg at 25 °C(SRC), using a fragment constant estimation method(2), is expected to exist solely in the particulate phase in the ambient atmosphere. Particulate-phase trimethylhexadecylammonium chloride may be removed from the air by wet and dry deposition(SRC). Source: Hazardous Substances Data Bank (HSDB)
  • Consumer Uses: Cleaning agent; Corrosion inhibitor; Softener and conditioner; Surface modifier; Surfactant (surface active agent) Source: EPA Chemical Data Reporting (CDR)
  • Industry Uses: Corrosion inhibitor; Processing aids, specific to petroleum production; Softener and conditioner; Surface modifier; CBI; Processing aids not otherwise specified; Surfactant (surface active agent) Source: EPA Chemical Data Reporting (CDR)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 112-03-8
CAS 112-03-8PubChem CID 8155

Verified chemistry for CAS 112-03-8

Stearyltrimethylammonium chloride

Stearyltrimethylammonium chloride is an organic molecular entity. — ChEBI

IUPAC name
trimethyl(octadecyl)azanium chloride
Molecular formula
C21H46ClN
Molecular weight
348.0 g/mol
Exact mass
347.3318782 Da
Monoisotopic mass
347.3318782 Da
Topological polar surface area
0.0 Ų
Molecular complexity
204.0
Formal charge
0
Hydrogen-bond donors
0
Hydrogen-bond acceptors
1
Rotatable bonds
17
Heavy atoms
23
Covalent units
2

Names and synonyms reported to PubChem

Trimethylstearylammonium chlorideStacCation ABAliquat 7Nissan cation ABQuaternium-10Arquad 18Stearyl trimethyl ammonium chloride
16 more reported names
Arquad 18-50Monostearyl trimethyl ammonium chlorideN,N,N-Trimethyl-1-octadecanaminium chlorideRefChem:871332N,N,N-trimethyloctadecan-1-aminium chlorideTrimethyloctadecylammonium chlorideOCTADECYLTRIMETHYLAMMONIUM CHLORIDE1-Octadecanaminium, N,N,N-trimethyl-, chlorideSteartrimonium chlorideStearyl trimethyl ammoium chlorideOctadecy trimethyl ammonium chloridetrimethyl octadecyl ammonium chlorideOctadecyl trimethyl ammonium chloridetrimethyloctadecylamine, chloridetrimethyl(octadecyl)azanium;chlorideEINECS 203-929-1
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D conformers
0
Machine-readable structure identifiers
SMILES
CCCCCCCCCCCCCCCCCC[N+](C)(C)C.[Cl-]
InChI
InChI=1S/C21H46N.ClH/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22(2,3)4;/h5-21H2,1-4H3;1H/q+1;/p-1
InChIKey
VBIIFPGSPJYLRR-UHFFFAOYSA-M

Evidence from additional scientific databases

NIH PubChem PUG-View
Exact identifier match8155

Attributed physical-property, hazard, environmental and use annotations.

  • Carcinogen Classification: Not listed by IARC. Certain nitrosamines are classified by IARC as either probably or possibly carcinogenic to humans (Groups 2A and 2B, respectively). (L135) Source: Toxin and Toxin Target Database (T3DB)
  • Note: This chemical does not meet GHS hazard criteria for 3.7% (10 of 268) of reports. Source: European Chemicals Agency (ECHA)
  • Signal: Danger Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H302 (88.1%): Harmful if swallowed [Warning Acute toxicity, oral]; H311 (54.5%): Toxic in contact with skin [Danger Acute toxicity, dermal]; H312 (19.8%): Harmful in contact with skin [Warning Acute toxicity, dermal]; H314 (79.1%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]; H318 (29.5%): Causes serious eye damage [Danger Serious eye damage/eye irritation]; H400 (71.6%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]; H410 (78.7%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P260, P262, P264, P264+P265, P270, P273, P280, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P321, P330, P361+P364, P362+P364, P363, P391, P405, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 268 reports by companies from 19 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Reported as not meeting GHS hazard criteria per 10 of 268 reports by companies.; There are 18 notifications provided by 258 of 268 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • Signal: Warning Source: NITE-CMC
  • GHS Hazard Statements: H302: Harmful if swallowed [Warning Acute toxicity, oral]; H312: Harmful in contact with skin [Warning Acute toxicity, dermal] Source: NITE-CMC
  • Precautionary Statement Codes: P264, P270, P280, P301+P317, P302+P352, P317, P321, P330, P362+P364, and P501 (click each P-code to see the statement) Source: NITE-CMC
  • Signal: Danger Source: Hazardous Chemical Information System (HCIS), Safe Work Australia
  • GHS Hazard Statements: H302: Harmful if swallowed [Warning Acute toxicity, oral]; H312: Harmful in contact with skin [Warning Acute toxicity, dermal]; H314: Causes severe skin burns and eye damage [Danger Skin corrosion/irritation] Source: Hazardous Chemical Information System (HCIS), Safe Work Australia
  • Precautionary Statement Codes: P260, P264, P270, P280, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P321, P330, P362+P364, P363, P405, and P501 (click each P-code to see the statement) Source: Hazardous Chemical Information System (HCIS), Safe Work Australia
  • Cosmetic Ingredient Review Conclusion: The CIR Expert Panel concluded the following ingredients are safe in the present practices of use and concentration described in the safety assessment when formulated to be non-irritating...Steartrimonium Chloride... Source: Cosmetic Ingredient Review (CIR)
  • Cosmetic Ingredient Review Finding(s): Safe for use in cosmetics, with qualifications Source: Cosmetic Ingredient Review (CIR)
  • Toxicity Summary: While quaternium-10 itself is not toxic, it is a nitrosating agent. Nitrosating agents may decompose and/or react to cause nitrosamine contamination. Nitrosamines are produced from secondary amines and amides in the presence of nitrite ions and are believed to be carcinogenic. Once in the body, nitrosamines are activated by cytochrome P-450 enzymes. They are then believed to induce their carcinogenic effects by forming DNA adducts at the N- and O-atoms. (L1889, L1890, A2878, A2879, A2880) Source: Toxin and Toxin Target Database (T3DB)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 1120-02-1
CAS 1120-02-1PubChem CID 70708

Verified chemistry for CAS 1120-02-1

Octadecyltrimethylammonium bromide

IUPAC name
trimethyl(octadecyl)azanium bromide
Molecular formula
C21H46BrN
Molecular weight
392.5 g/mol
Exact mass
391.28136 Da
Monoisotopic mass
391.28136 Da
Topological polar surface area
0.0 Ų
Molecular complexity
204.0
Formal charge
0
Hydrogen-bond donors
0
Hydrogen-bond acceptors
1
Rotatable bonds
17
Heavy atoms
23
Covalent units
2

Names and synonyms reported to PubChem

Steartrimonium BromideBPW1DD4IZ8CATINAL STBODTEA Br cpdRefChem:889163214-294-5Trimethyloctadecylammonium bromideOctMAB
16 more reported names
N,N,N-Trimethyloctadecan-1-aminium bromideStearyltrimethylammonium BromideOctadecy trimethyl ammonium bromideTrimethylstearylammonium Bromide1-Octadecanaminium, N,N,N-trimethyl-, bromideOTABTrimethyl-1-octylammonium bromidetrimethyl(octadecyl)azanium;bromideStearyltrimethylammonium bromide (STAB)Trimethyloctadecylammonium (bromide)1-Octadecanaminium, N,N,N-trimethyl-, bromide (1:1)UNII-BPW1DD4IZ8C21H46BrNStearyl Trimethyl Ammoium bromideEINECS 214-294-5Ammonium, trimethyloctadecyl-, bromide
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D conformers
0
Machine-readable structure identifiers
SMILES
CCCCCCCCCCCCCCCCCC[N+](C)(C)C.[Br-]
InChI
InChI=1S/C21H46N.BrH/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22(2,3)4;/h5-21H2,1-4H3;1H/q+1;/p-1
InChIKey
SZEMGTQCPRNXEG-UHFFFAOYSA-M

Evidence from additional scientific databases

NIH PubChem PUG-View
Exact identifier match70708

Attributed physical-property, hazard, environmental and use annotations.

  • Signal: Danger Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H302 (13%): Harmful if swallowed [Warning Acute toxicity, oral]; H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]; H317 (10.9%): May cause an allergic skin reaction [Warning Sensitization, Skin]; H318 (10.9%): Causes serious eye damage [Danger Serious eye damage/eye irritation]; H319 (89.1%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H335 (87%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P261, P264, P264+P265, P270, P271, P272, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P305+P354+P338, P317, P319, P321, P330, P332+P317, P333+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 46 reports by companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • Cosmetic Ingredient Review Conclusion: The CIR Expert Panel concluded the following ingredients are safe in the present practices of use and concentration described in the safety assessment when formulated to be non-irritating...Steartrimonium Bromide... Source: Cosmetic Ingredient Review (CIR)
  • Cosmetic Ingredient Review Finding(s): Safe for use in cosmetics, with qualifications Source: Cosmetic Ingredient Review (CIR)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 17301-53-0
CAS 17301-53-0PubChem CID 3014969

Verified chemistry for CAS 17301-53-0

Behentrimonium Chloride

IUPAC name
docosyl(trimethyl)azanium chloride
Molecular formula
C25H54ClN
Molecular weight
404.2 g/mol
Exact mass
403.3944784 Da
Monoisotopic mass
403.3944784 Da
Topological polar surface area
0.0 Ų
Molecular complexity
253.0
Formal charge
0
Hydrogen-bond donors
0
Hydrogen-bond acceptors
1
Rotatable bonds
21
Heavy atoms
27
Covalent units
2

Names and synonyms reported to PubChem

Docosyltrimethylammonium chlorideX7GNG3S47T1-Docosanaminium, N,N,N-trimethyl-, chlorideEINECS 241-327-0BEHENTRIMONIUMGENAMIN BTLFN,N,N-Trimethyl-1-docosanaminium chloride1-Docosanaminium, N,N,N-trimethyl-, chloride (1:1)
16 more reported names
behenyltrimethylammonium chlorideVARISOFT BT 85 PELLETSINCROQUAT BEHENYL TMC-85RefChem:561201BEHENTRIMONIUM CHLORIDE [INCI]241-327-0926-569-3N,N,N-Trimethyldocosan-1-aminium chloridedocosyl(trimethyl)azanium;chlorideUNII-X7GNG3S47TBehentrimonium Chloride (>80%)docosyl(trimethyl)azanium,chlorideBehenyltrimonium chloridebehenyltrimethylammoniumchloridedocosyltrimethylazanium chlorideTrimethylbehenylammonium chloride
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D conformers
0
Machine-readable structure identifiers
SMILES
CCCCCCCCCCCCCCCCCCCCCC[N+](C)(C)C.[Cl-]
InChI
InChI=1S/C25H54N.ClH/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24-25-26(2,3)4;/h5-25H2,1-4H3;1H/q+1;/p-1
InChIKey
YSJGOMATDFSEED-UHFFFAOYSA-M

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 57-09-0
CAS 57-09-0PubChem CID 5974

Verified chemistry for CAS 57-09-0

Hexadecyltrimethylammonium Bromide

IUPAC name
hexadecyl(trimethyl)azanium bromide
Molecular formula
C19H42BrN
Molecular weight
364.4 g/mol
Exact mass
363.25006 Da
Monoisotopic mass
363.25006 Da
Topological polar surface area
0.0 Ų
Molecular complexity
181.0
Formal charge
0
Hydrogen-bond donors
0
Hydrogen-bond acceptors
1
Rotatable bonds
15
Heavy atoms
21
Covalent units
2

Names and synonyms reported to PubChem

Cetrimonium bromideCetyltrimethylammonium bromideBromatCETABCentimideCtmabAcetoquat CTABCee dee
16 more reported names
Cetyl trimethyl ammonium bromideTrimethylcetylammonium bromideBromuro de cetrimonioN-Cetyltrimethylammonium bromideBromure de cetrimoniumCetrimonii bromidumTrimethylhexadecylammonium bromideCetrimonio bromuroN-HEXADECYLTRIMETHYLAMMONIUM BROMIDEPalmityltrimethyl ammonium bromideN,N,N-Trimethyl-1-hexadecanaminium bromideN,N,N-Trimethylcetylammonium bromideSumquat 6030N-Hexadecyl-N,N,N-trimethylammonium bromideL64N7M9BWRNSC-32927
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D conformers
0
Machine-readable structure identifiers
SMILES
CCCCCCCCCCCCCCCC[N+](C)(C)C.[Br-]
InChI
InChI=1S/C19H42N.BrH/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(2,3)4;/h5-19H2,1-4H3;1H/q+1;/p-1
InChIKey
LZZYPRNAOMGNLH-UHFFFAOYSA-M

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Official source and provenance

Registered source
ASEAN Cosmetic Directive annexes
Source reference
ASEAN Annex VI, reference 44
Source record ID
VI-44
Source version
2026-1
Source language
English
Translation status
Original is English
Source updated
2026-06-22
Snapshot checked
2026-08-30 04:44 UTC
Validation method
pdfplumber ruled-table extraction with per-annex reviewed counts
SHA-256
ffad59f6c01a92c82042c54203ee14969425c2a82bd04c2f4012ff82513e69f1

Registered dataset notes

Dataset coverage
Banned, restricted and positive-list substances under the harmonised ASEAN framework
Authority note
Regional directive; member-state transitions and deviations still require local verification
Inspect the exact official sourceRegulator guidance

How this record fits the market dataset

2224
current ASEAN records
247
records marked Permitted list with conditions
2224
records from this source version
1930
market records with CAS identity

Status distribution

Permitted list with conditions: 247Prohibited: 1728Restricted: 249

Condition text is present on 462 of 2224 current records. An empty condition field is interpreted according to the record type above; it is never converted into an unrestricted-use claim.

ASEAN market context

Complete regional annex dataset

Coverage version: ASEAN Cosmetic Directive annexes 2026-1, 22 June 2026

Annexes II, III, IV, VI and VII covering prohibited, restricted and positive-list substances.

Verification checklist

  1. Search all ACD annexes by name and identifiers.
  2. Apply product type, maximum level and warning conditions.
  3. Confirm the target member state's adoption and transition date.
  4. Complete the local notification and responsible-company requirements.

Official market sources

Verification workflow and record completeness

Before using this result in a compliance decision

  1. Confirm that “Alkyl (C ) trimethyl ammonium bromide and 12-22 chloride) (+) Behentrimonium chloride (11) (CAS No. 17301- 53-0), cetrimonium bromide (CAS No. 57-09-0), cetrimonium chloride (12) (CAS No. 112-02- 7), laurtrimonium bromide, (CAS No. 1119- 94-4), laurtrimonium chloride (CAS No. 112- 00-5), steartrimonium bromide (CAS No. 1120-02-1), steartrimonium chloride (12) (CAS No. 112-03-8)” and every CAS/EC identifier refer to the material in your supplier specification.
  2. Search all ACD annexes by name and identifiers.
  3. Apply product type, maximum level and warning conditions.
  4. Confirm the target member state's adoption and transition date.
  5. Complete the local notification and responsible-company requirements.
  6. Document the source version and recheck the regulator before manufacture, notification or market placement.

Fields available in this record

  • Official substance nameAvailable
  • CASAvailable
  • ECAvailable
  • Separate condition textAvailable
  • Effective dateNot supplied
  • Snapshot hash and methodAvailable

Questions this page answers

This identity appears on a market positive list for the list function represented by the source record. Confirm that the intended function and product use fall within the list scope and every stated condition.

Positive-list presence is purpose-specific and is not blanket approval for every cosmetic use. Regional annex coverage does not replace member-state implementation dates, notifications or national deviations.

The record cites ASEAN Annex VI, reference 44, source version 2026-1. Open the official source.

No. CAS helps resolve identity, but jurisdictions can classify the same substance differently and can apply different product scopes, limits, warnings and transition dates.

Stable citation

Alkyl (C ) trimethyl ammonium bromide and 12-22 chloride) (+) Behentrimonium chloride (11) (CAS No. 17301- 53-0), cetrimonium bromide (CAS No. 57-09-0), cetrimonium chloride (12) (CAS No. 112-02- 7), laurtrimonium bromide, (CAS No. 1119- 94-4), laurtrimonium chloride (CAS No. 112- 00-5), steartrimonium bromide (CAS No. 1120-02-1), steartrimonium chloride (12) (CAS No. 112-03-8). ASEAN Annex VI, reference 44. ASEAN. Source version 2026-1. CosIng Checker regulatory record: https://cosingchecker.com/regulations/asean/records/4303/

Cite the regulator as the legal authority. This page is a structured evidence index and verification aid, not a substitute for the official text or professional legal assessment.

Interpretation and limits for ASEAN

This identity appears on a market positive list for the list function represented by the source record.

Confirm that the intended function and product use fall within the list scope and every stated condition.

How to interpret the legal role

The cited row forms part of a binding rule or legally incorporated list for this market.

Evidence on this page

  • Recorded outcome: Permitted list with conditions
  • Legal role: Binding rule
  • Source version: 2026-1

What it does not prove

Regional annex coverage does not replace member-state implementation dates, notifications or national deviations.

Further authoritative substance research

These sources can add identity, safety, exposure or hazard context. A link is not evidence that the database contains this exact substance, and none of these sources overrides the market decision above.

Cosmetic Ingredient Review safety assessments

Expert Panel conclusions, assessed ingredient groups, use conditions, dates and report documents

Independent expert review considered by FDA; not a government approval or binding market rule

Research this identity at the source

FDA Global Substance Registration System

UNII identifiers, preferred names, substance types, codes and public substance relationships

Identity registry only; UNII availability does not imply FDA review or approval

Research this identity at the source

ILO/WHO International Chemical Safety Cards

Hazards, symptoms, first aid, storage, incompatibilities and physical properties for covered chemicals

International occupational chemical-safety reference; not cosmetic-use approval

Research this identity at the source

Japan NITE-CHRIP

Chemical identity, Japanese and foreign legal lists, GHS hazards and exposure-related information

Chemical-management evidence; cosmetic status remains governed by the applicable MHLW standard and market rules

Research this identity at the source

NIOSH Pocket Guide to Chemical Hazards

REL, PEL, IDLH, properties, exposure routes, symptoms, target organs, first aid and measurement methods for covered workplace chemicals

US occupational-health guidance and limits; not a cosmetic ingredient decision

Research this identity at the source

OECD eChemPortal

Gateway to authority-owned physical-property, fate, ecotoxicity, toxicity, exposure and GHS records

Discovery gateway; each linked authority remains responsible for its data

Research this identity at the source

US EPA CompTox CTX APIs

API key required for import

DTXSID identity, experimental and predicted properties, toxicity, bioactivity, exposure and environmental data

Scientific and computational evidence; predictions must remain labelled and do not determine cosmetic legality

Research this identity at the source