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Permitted list with conditionsBinding ruleASEANOriginal is EnglishOfficial-source import checked

Salicylic acid (69-72-7) and its salts(1) : Calcium salicylate (CAS No. 824-35- 1), Magnesium salicylate (CAS No. 18917-89- 0), MEA-salicylate (CAS No. 59866-70-5), Sodium salicylate (CAS No. 54-21-7), Potassium salicylate (CAS No. 578-36-9), TEA- salicylate (CAS No. 2174-16-5)

Salicylic acid (69-72-7) and its salts(1) : Calcium salicylate (CAS No. 824-35- 1), Magnesium salicylate (CAS No. 18917-89- 0), MEA-salicylate (CAS No. 59866-70-5), Sodium salicylate (CAS No. 54-21-7), Potassium salicylate (CAS No. 578-36-9), TEA- salicyl

ASEAN Annex VI lists this record among preservatives allowed for cosmetic use. Member-state transition rules and deviations still require local verification.

All ASEAN recordsOpen ingredient profileCompare all marketsOpen official source

Regulatory decision and full conditions

Status
Permitted list with conditions
Legal role
Binding rule
Regulatory summary
ASEAN Annex VI lists this record among preservatives allowed for cosmetic use. Member-state transition rules and deviations still require local verification.
Conditions and restrictions
0.5% (acid) 0.5% (acid) · Salicylic acid: Not to be used in products for children under three years of age. Not to be used in oral products. Not to be used in applications that may lead to exposure of the end-user’s lungs by inhalation. Salicylic acid salts: Not to be used in preparations for children under three years of age, except for shampoos · Salicylic acid: Not to be used for children under three years of age (2.1) Salicylic acid salts: Not to be used for children under three years of age (2.2)

Substance identity

Official source name
Salicylic acid (69-72-7) and its salts(1) : Calcium salicylate (CAS No. 824-35- 1), Magnesium salicylate (CAS No. 18917-89- 0), MEA-salicylate (CAS No. 59866-70-5), Sodium salicylate (CAS No. 54-21-7), Potassium salicylate (CAS No. 578-36-9), TEA- salicylate (CAS No. 2174-16-5)
CAS
69-72-7; 824-35-1; 18917-89-0; 59866-70-5; 54-21-7; 578-36-9; 2174-16-5
EC
200-712-3
Identity mapping
cas_number
Linked ingredient
SALICYLIC ACID
Search this identity across the siteCAS 69-72-7CAS 824-35-1CAS 18917-89-0CAS 59866-70-5CAS 54-21-7CAS 578-36-9CAS 2174-16-5EC 200-712-3

Linked CosIng identity data

Names and aliases

SALICYLIC ACIDsalicylic acidacidum salicylicum

CosIng description: Salicylic acid

EU inventory restriction note: III/98 V/3

Recorded cosmetic function: ANTI-SEBORRHEIC, FRAGRANCE, HAIR CONDITIONING, KERATOLYTIC, PRESERVATIVE, SKIN CONDITIONING

Function pages:ANTI-SEBORRHEIC, FRAGRANCE, HAIR CONDITIONING, KERATOLYTIC, PRESERVATIVE, SKIN CONDITIONING

View the complete ingredient profile

Cross-market snapshot for this identity

Exact linked records currently present in this site. An absent market means no imported exact match, not permission to use the substance.

9 market datasets

Great Britain

Permitted list with conditionsRestricted

2 linked records · 2 with specific conditions

Open supporting record

New Zealand

Permitted list with conditionsRestricted

8 linked records · 8 with specific conditions

Open supporting record

ASEAN

Current record
Permitted list with conditionsRestricted

2 linked records · 2 with specific conditions

Open supporting record
PubChem 2D chemical structure for CAS 18917-89-0
CAS 18917-89-0PubChem CID 54684589

Verified chemistry for CAS 18917-89-0

(T-4)-Bis(2-(hydroxy-kappaO)benzoato-kappaO)magnesium

IUPAC name
magnesium bis(2-carboxyphenolate)
Molecular formula
C14H10MgO6
Molecular weight
298.53 g/mol
Exact mass
298.0327797 Da
Monoisotopic mass
298.0327797 Da
Topological polar surface area
121.0 Ų
Molecular complexity
133.0
Formal charge
0
Hydrogen-bond donors
2
Hydrogen-bond acceptors
6
Rotatable bonds
2
Heavy atoms
21
Covalent units
3

Names and synonyms reported to PubChem

Magnesium salicylateMagnesium salicylate anhydrousMagnesium disalicylateBackache reliefJQ69D454N1Backache CapletsBayer Select BackacheBackprin
16 more reported names
DoansBack Pain ReliefDoans Extra StrengthDoans Maximum StrengthMedique Back Pain ReliefRefChem:408391Unishield Back Pain ReliefMaximum Strength Backache ReliefMedique at Home Back Pain ReliefBack Pain Relief Extra Strength Doans242-669-3Magnesium Salicylate TetrahydrateMaganmagnesiumsalicylateMobidinmagnesium;2-carboxyphenolate
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D conformers
0
Machine-readable structure identifiers
SMILES
C1=CC=C(C(=C1)C(=O)O)[O-].C1=CC=C(C(=C1)C(=O)O)[O-].[Mg+2]
InChI
InChI=1S/2C7H6O3.Mg/c2*8-6-4-2-1-3-5(6)7(9)10;/h2*1-4,8H,(H,9,10);/q;;+2/p-2
InChIKey
MQHWFIOJQSCFNM-UHFFFAOYSA-L

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 2174-16-5
CAS 2174-16-5PubChem CID 25213

Verified chemistry for CAS 2174-16-5

Trolamine Salicylate

IUPAC name
2-[bis(2-hydroxyethyl)amino]ethanol;2-hydroxybenzoic acid
Molecular formula
C13H21NO6
Molecular weight
287.31 g/mol
Exact mass
287.13688739 Da
Monoisotopic mass
287.13688739 Da
Topological polar surface area
121.0 Ų
Molecular complexity
189.0
Formal charge
0
Hydrogen-bond donors
5
Hydrogen-bond acceptors
7
Rotatable bonds
7
Heavy atoms
20
Covalent units
2

Names and synonyms reported to PubChem

Triethanolamine salicylateTEA-SalicylateTEA salicylateNeo heliopan tsNeotan wArthricreamH8O4040BHDTrolamine salicylate (USP)
16 more reported names
Trolamine salicylate [USP]CannaflexHempvanaArthritis CreamArthritis LeaderArthritis ReliefAsper-FlexAsper-Flex CreamTrolamin SalicylateArthritis with AloeHempvana Pain ReliefArthricream with AloeDCH Arthritis ReliefXCEPTOL PAINCopperlife Pain ReliefCBD Pain Relief Cream
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D conformers
0
Machine-readable structure identifiers
SMILES
C1=CC=C(C(=C1)C(=O)O)O.C(CO)N(CCO)CCO
InChI
InChI=1S/C7H6O3.C6H15NO3/c8-6-4-2-1-3-5(6)7(9)10;8-4-1-7(2-5-9)3-6-10/h1-4,8H,(H,9,10);8-10H,1-6H2
InChIKey
UEVAMYPIMMOEFW-UHFFFAOYSA-N

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 54-21-7
CAS 54-21-7PubChem CID 16760658

Verified chemistry for CAS 54-21-7

Sodium Salicylate

Sodium salicylate is an organic molecular entity. — ChEBI

IUPAC name
sodium 2-hydroxybenzoate
Molecular formula
C7H5NaO3
Molecular weight
160.10 g/mol
Exact mass
160.01363830 Da
Monoisotopic mass
160.01363830 Da
Topological polar surface area
60.4 Ų
Molecular complexity
138.0
Formal charge
0
Hydrogen-bond donors
1
Hydrogen-bond acceptors
3
Rotatable bonds
1
Heavy atoms
11
Covalent units
2

Names and synonyms reported to PubChem

EnterosalicylKerasalicylAlysineBenzoic acid, 2-hydroxy-, monosodium saltNatrum salicylicumSalicylic acid sodium saltsalicylate sodiumMonosodium 2-hydroxybenzoate
16 more reported names
Natrii salicylasWIQ1H85SYPSalicylate, sodiumNSC-202167Benzoic acid, 2-hydroxy-, sodium salt (1:1)Sod salPro-PrinSaliGard 60RefChem:6246UNI-SOLUNI-SOL 60Aspen Sodium Salicylate 48.6%AquaPrime Liquid Sodium SalicylateAquasource Aqua-Prin Water Soluble Sodium Salicylate200-198-0Salsonin
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D conformers
0
Machine-readable structure identifiers
SMILES
C1=CC=C(C(=C1)C(=O)[O-])O.[Na+]
InChI
InChI=1S/C7H6O3.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H,(H,9,10);/q;+1/p-1
InChIKey
ABBQHOQBGMUPJH-UHFFFAOYSA-M

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 578-36-9
CAS 578-36-9PubChem CID 23664627

Verified chemistry for CAS 578-36-9

Potassium Salicylate

IUPAC name
potassium 2-hydroxybenzoate
Molecular formula
C7H5KO3
Molecular weight
176.21 g/mol
Exact mass
175.98757550 Da
Monoisotopic mass
175.98757550 Da
Topological polar surface area
60.4 Ų
Molecular complexity
138.0
Formal charge
0
Hydrogen-bond donors
1
Hydrogen-bond acceptors
3
Rotatable bonds
1
Heavy atoms
11
Covalent units
2

Names and synonyms reported to PubChem

Salicylic acid potassium saltK91YT16P5MUNII-K91YT16P5MBenzoic acid, 2-hydroxy-, monopotassium saltPOTASSIUM SALICYLATE [MI]EINECS 209-421-6Benzoic acid, 2-hydroxy-, potassium salt (1:1)POTASSIUM SALICYLATE [VANDF]
11 more reported names
POTASSIUM SALICYLATE [WHO-DD]RefChem:175593POTASSIUM SALICYLATE [INCI]209-421-6potassium,2-hydroxybenzoatepotassium;2-hydroxybenzoateSALICYLIC ACID (POTASSIUM)PotassiumsalicylateAS-15221FT-0632428EN300-20085
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D conformers
0
Machine-readable structure identifiers
SMILES
C1=CC=C(C(=C1)C(=O)[O-])O.[K+]
InChI
InChI=1S/C7H6O3.K/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H,(H,9,10);/q;+1/p-1
InChIKey
FRMWBRPWYBNAFB-UHFFFAOYSA-M

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 59866-70-5
CAS 59866-70-5PubChem CID 3085170

Verified chemistry for CAS 59866-70-5

Salicylic acid monoethanolamine

IUPAC name
2-aminoethanol;2-hydroxybenzoic acid
Molecular formula
C9H13NO4
Molecular weight
199.20 g/mol
Exact mass
199.08445790 Da
Monoisotopic mass
199.08445790 Da
Topological polar surface area
104.0 Ų
Molecular complexity
143.0
Formal charge
0
Hydrogen-bond donors
4
Hydrogen-bond acceptors
5
Rotatable bonds
2
Heavy atoms
14
Covalent units
2

Names and synonyms reported to PubChem

MEA-SALICYLATEUNII-078ORG4DXO078ORG4DXOEINECS 261-963-2Salicylic acid, compound with 2-aminoethanol (1:1)Monoethanolamine SalicylateSALICYLIC ACID ETHANOLAMINE SALTSALICYLIC ACID, 2-AMINOETHANOL SALT
7 more reported names
SALICYLIC ACID MONOETHANOLAMINE [WHO-DD]ETHANOL, 2-AMINO-, 2-HYDROXYBENZOATE (SALT)RefChem:180924MEA-SALICYLATE [INCI]Ethanolamine salicylate [WHO-DD]WGPVWXXJNUNBNB-UHFFFAOYSA-N2-Hydroxybenzoic acid--2-aminoethan-1-ol (1/1)
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D conformers
0
Machine-readable structure identifiers
SMILES
C1=CC=C(C(=C1)C(=O)O)O.C(CO)N
InChI
InChI=1S/C7H6O3.C2H7NO/c8-6-4-2-1-3-5(6)7(9)10;3-1-2-4/h1-4,8H,(H,9,10);4H,1-3H2
InChIKey
WGPVWXXJNUNBNB-UHFFFAOYSA-N

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 69-72-7
CAS 69-72-7PubChem CID 338

Verified chemistry for CAS 69-72-7

Salicylic Acid

Salicylic acid is a monohydroxybenzoic acid that is benzoic acid with a hydroxy group at the ortho position. It is obtained from the bark of the white willow and wintergreen leaves. It has a role as an antiinfective agent, an antifungal agent, a plant hormone, a keratolytic drug, an EC 1.11.1.11 (L-ascorbate peroxidase) inhibitor, a plant metabolite and an algal metabolite. It is a conjugate acid of a salicylate. — ChEBI

IUPAC name
2-hydroxybenzoic acid
Molecular formula
C7H6O3
Molecular weight
138.12 g/mol
Exact mass
138.031694049 Da
Monoisotopic mass
138.031694049 Da
XLogP3
2.3
Topological polar surface area
57.5 Ų
Molecular complexity
133.0
Formal charge
0
Hydrogen-bond donors
2
Hydrogen-bond acceptors
3
Rotatable bonds
1
Heavy atoms
10
Covalent units
1

Names and synonyms reported to PubChem

o-hydroxybenzoic acid2-Carboxyphenolo-CarboxyphenolRetarder WRutranexSalonilKeralytDuoplant
16 more reported names
FreezoneSaligelIonilPsoriacid-S-stiftBenzoic acid, 2-hydroxy-Stri-DexSalicylic acid soapVerrugonSalicylic acid collodionPhenol-2-carboxylic acid2-Hydroxybenzenecarboxylic acidTrans-Ver-SalOrthohydroxybenzoic acidAcidum salicylicumAcido salicilicoIonil-Plus
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D pharmacophore features
5
3D rings
1
3D hydrophobes
0
3D acceptor features
2
3D donor features
1
3D anionic centres
1
3D cationic centres
0
3D conformers
3
Effective 3D rotors
1.0
Machine-readable structure identifiers
SMILES
C1=CC=C(C(=C1)C(=O)O)O
InChI
InChI=1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10)
InChIKey
YGSDEFSMJLZEOE-UHFFFAOYSA-N

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 824-35-1
CAS 824-35-1PubChem CID 54684600

Verified chemistry for CAS 824-35-1

Calcium Salicylate

IUPAC name
calcium bis(2-carboxyphenolate)
Molecular formula
C14H10CaO6
Molecular weight
314.30 g/mol
Exact mass
314.0103289 Da
Monoisotopic mass
314.0103289 Da
Topological polar surface area
121.0 Ų
Molecular complexity
133.0
Formal charge
0
Hydrogen-bond donors
2
Hydrogen-bond acceptors
6
Rotatable bonds
2
Heavy atoms
21
Covalent units
3

Names and synonyms reported to PubChem

Calcium disalicylateBenzoic acid, 2-hydroxy-, calcium salt (2:1)0841QCS0DKRefChem:573557212-525-4Calcium 2-hydroxybenzoateUNII-0841QCS0DKEINECS 212-525-4
5 more reported names
CALCIUMSALICYLATEcalcium bis(2-hydroxybenzoate)CALCIUM SALICYLATE [II]CALCIUM SALICYLATE [WHO-DD]DB-056609
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D conformers
0
Machine-readable structure identifiers
SMILES
C1=CC=C(C(=C1)C(=O)O)[O-].C1=CC=C(C(=C1)C(=O)O)[O-].[Ca+2]
InChI
InChI=1S/2C7H6O3.Ca/c2*8-6-4-2-1-3-5(6)7(9)10;/h2*1-4,8H,(H,9,10);/q;;+2/p-2
InChIKey
VBIGULIJWJPALH-UHFFFAOYSA-L

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Official source and provenance

Registered source
ASEAN Cosmetic Directive annexes
Source reference
ASEAN Annex VI, reference 3
Source record ID
VI-3
Source version
2026-1
Source language
English
Translation status
Original is English
Source updated
2026-06-22
Snapshot checked
2026-08-30 04:44 UTC
Validation method
pdfplumber ruled-table extraction with per-annex reviewed counts
SHA-256
ffad59f6c01a92c82042c54203ee14969425c2a82bd04c2f4012ff82513e69f1

Registered dataset notes

Dataset coverage
Banned, restricted and positive-list substances under the harmonised ASEAN framework
Authority note
Regional directive; member-state transitions and deviations still require local verification
Inspect the exact official sourceRegulator guidance

How this record fits the market dataset

2224
current ASEAN records
247
records marked Permitted list with conditions
2224
records from this source version
1930
market records with CAS identity

Status distribution

Permitted list with conditions: 247Prohibited: 1728Restricted: 249

Condition text is present on 462 of 2224 current records. An empty condition field is interpreted according to the record type above; it is never converted into an unrestricted-use claim.

ASEAN market context

Complete regional annex dataset

Coverage version: ASEAN Cosmetic Directive annexes 2026-1, 22 June 2026

Annexes II, III, IV, VI and VII covering prohibited, restricted and positive-list substances.

Verification checklist

  1. Search all ACD annexes by name and identifiers.
  2. Apply product type, maximum level and warning conditions.
  3. Confirm the target member state's adoption and transition date.
  4. Complete the local notification and responsible-company requirements.

Official market sources

Verification workflow and record completeness

Before using this result in a compliance decision

  1. Confirm that “Salicylic acid (69-72-7) and its salts(1) : Calcium salicylate (CAS No. 824-35- 1), Magnesium salicylate (CAS No. 18917-89- 0), MEA-salicylate (CAS No. 59866-70-5), Sodium salicylate (CAS No. 54-21-7), Potassium salicylate (CAS No. 578-36-9), TEA- salicylate (CAS No. 2174-16-5)” and every CAS/EC identifier refer to the material in your supplier specification.
  2. Search all ACD annexes by name and identifiers.
  3. Apply product type, maximum level and warning conditions.
  4. Confirm the target member state's adoption and transition date.
  5. Complete the local notification and responsible-company requirements.
  6. Document the source version and recheck the regulator before manufacture, notification or market placement.

Fields available in this record

  • Official substance nameAvailable
  • CASAvailable
  • ECAvailable
  • Separate condition textAvailable
  • Effective dateNot supplied
  • Snapshot hash and methodAvailable

Questions this page answers

This identity appears on a market positive list for the list function represented by the source record. Confirm that the intended function and product use fall within the list scope and every stated condition.

Positive-list presence is purpose-specific and is not blanket approval for every cosmetic use. Regional annex coverage does not replace member-state implementation dates, notifications or national deviations.

The record cites ASEAN Annex VI, reference 3, source version 2026-1. Open the official source.

No. CAS helps resolve identity, but jurisdictions can classify the same substance differently and can apply different product scopes, limits, warnings and transition dates.

Stable citation

Salicylic acid (69-72-7) and its salts(1) : Calcium salicylate (CAS No. 824-35- 1), Magnesium salicylate (CAS No. 18917-89- 0), MEA-salicylate (CAS No. 59866-70-5), Sodium salicylate (CAS No. 54-21-7), Potassium salicylate (CAS No. 578-36-9), TEA- salicylate (CAS No. 2174-16-5). ASEAN Annex VI, reference 3. ASEAN. Source version 2026-1. CosIng Checker regulatory record: https://cosingchecker.com/regulations/asean/records/4261/

Cite the regulator as the legal authority. This page is a structured evidence index and verification aid, not a substitute for the official text or professional legal assessment.

Interpretation and limits for ASEAN

This identity appears on a market positive list for the list function represented by the source record.

Confirm that the intended function and product use fall within the list scope and every stated condition.

How to interpret the legal role

The cited row forms part of a binding rule or legally incorporated list for this market.

Evidence on this page

  • Recorded outcome: Permitted list with conditions
  • Legal role: Binding rule
  • Source version: 2026-1

What it does not prove

Regional annex coverage does not replace member-state implementation dates, notifications or national deviations.

Further authoritative substance research

These sources can add identity, safety, exposure or hazard context. A link is not evidence that the database contains this exact substance, and none of these sources overrides the market decision above.

Cosmetic Ingredient Review safety assessments

Expert Panel conclusions, assessed ingredient groups, use conditions, dates and report documents

Independent expert review considered by FDA; not a government approval or binding market rule

Research this identity at the source

FDA Global Substance Registration System

UNII identifiers, preferred names, substance types, codes and public substance relationships

Identity registry only; UNII availability does not imply FDA review or approval

Research this identity at the source

ILO/WHO International Chemical Safety Cards

Hazards, symptoms, first aid, storage, incompatibilities and physical properties for covered chemicals

International occupational chemical-safety reference; not cosmetic-use approval

Research this identity at the source

Japan NITE-CHRIP

Chemical identity, Japanese and foreign legal lists, GHS hazards and exposure-related information

Chemical-management evidence; cosmetic status remains governed by the applicable MHLW standard and market rules

Research this identity at the source

NIOSH Pocket Guide to Chemical Hazards

REL, PEL, IDLH, properties, exposure routes, symptoms, target organs, first aid and measurement methods for covered workplace chemicals

US occupational-health guidance and limits; not a cosmetic ingredient decision

Research this identity at the source

OECD eChemPortal

Gateway to authority-owned physical-property, fate, ecotoxicity, toxicity, exposure and GHS records

Discovery gateway; each linked authority remains responsible for its data

Research this identity at the source

US EPA CompTox CTX APIs

API key required for import

DTXSID identity, experimental and predicted properties, toxicity, bioactivity, exposure and environmental data

Scientific and computational evidence; predictions must remain labelled and do not determine cosmetic legality

Research this identity at the source