Why does CAS 69-72-7 appear in more than one EU cosmetic annex?

A substance identified by CAS 69-72-7 may appear in multiple EU cosmetic regulation annexes when it is subject to different conditions in different contexts — for example, restricted under Annex III with specific conditions, while also appearing in Annex IV as an approved colorant under separate entry conditions. Each entry must be reviewed individually.

How do I check if my formula contains a substance with CAS 69-72-7?

Use the INCI Checker on CosIng Checker with INCI names, CAS numbers or EC numbers. Paste CAS 69-72-7 to screen it directly, then review every linked annex record and supplier document.

CAS 2 records

CAS 69-72-7

Q: How do I use CAS 69-72-7 for compliance screening?

Cross-reference CAS 69-72-7 against your raw material specification sheets and CoA documents. When it appears in Annex II, verify absence. When it appears in Annex III, verify that concentration limits and product type conditions are met. All annex entries sharing this CAS number are listed on this page.

CAS 69-72-7 matches 2 EU annex records across Annex II–VI of Regulation 1223/2009.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 69-72-7

CAS 69-72-7PubChem CID 338

Salicylic Acid

Salicylic acid is a monohydroxybenzoic acid that is benzoic acid with a hydroxy group at the ortho position. It is obtained from the bark of the white willow and wintergreen leaves. It has a role as an antiinfective agent, an antifungal agent, a plant hormone, a keratolytic drug, an EC 1.11.1.11 (L-ascorbate peroxidase) inhibitor, a plant metabolite and an algal metabolite. It is a conjugate acid of a salicylate. — ChEBI

IUPAC name: 2-hydroxybenzoic acid

Molecular formula: C7H6O3
Molecular weight: 138.12 g/mol
Exact mass: 138.031694049 Da
XLogP3: 2.3
Topological polar surface area: 57.5 Å²
Hydrogen-bond donors: 2
Hydrogen-bond acceptors: 3
Covalent units: 1
Defined stereocentres: 0

Also known as

o-hydroxybenzoic acid2-Carboxyphenolo-CarboxyphenolRetarder WRutranexSalonilKeralytDuoplant

16 more reported names

FreezoneSaligelIonilPsoriacid-S-stiftBenzoic acid, 2-hydroxy-Stri-DexSalicylic acid soapVerrugonSalicylic acid collodionPhenol-2-carboxylic acid2-Hydroxybenzenecarboxylic acidTrans-Ver-SalOrthohydroxybenzoic acidAcidum salicylicumAcido salicilicoIonil-Plus

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:16914
ChEMBL:CHEMBL424
EPA DTXSID:DTXSID7026368
PubMed:40976440
PubMed:37531284
PubMed:37499995
PubMed:36416909
PubMed:32020584
PubMed:31734321
PubMed:30842373
PubMed:29968805
PubMed:28594102
PubMed:25108154
PubMed:24685503
PubMed:24085192

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Records for CAS 69-72-7

2 total

Annex

III

Entry

SALICYLIC ACID

Benzoic acid, 2-hydroxy-

(a) (b) (c) Not to be used for children under 3 years of age* * Solely for products which might be used for children under 3 years of age.

200-712-3

Max concentration CMR

How CAS 69-72-7 is used on this site

CAS 69-72-7 is the Chemical Abstracts Service identifier used to pin this page to a specific substance. In the current dataset, 2 EU annex records share this identifier, which helps you cross-check whether the same substance appears under one regulatory context or several.

Use this page when a supplier specification, SDS or raw-material dossier gives you CAS 69-72-7 and you need to see every linked Annex II–VI record in one place. The entry cards above are the quickest route to concentration limits, warnings, annex placement and product-type conditions.

Frequently asked questions

A substance identified by CAS 69-72-7 may appear in multiple EU cosmetic regulation annexes when it is subject to different conditions in different contexts. For example, a substance might be restricted under Annex III with specific conditions, and the same CAS might also appear in Annex IV as an approved colorant under separate entry conditions. Each entry must be reviewed individually.

Cross-reference the CAS number against your raw material specification sheets and CoA documents. When a CAS appears in Annex II, verify absence. When it appears in Annex III, verify that concentration limits and product type conditions are met in your formulation. All annex entries sharing this CAS number are listed above.

A CAS number is assigned by the Chemical Abstracts Service (USA) and is globally recognised. An EC number is a European Commission identifier from inventories such as EINECS, ELINCS or the NLP list. Both identifiers may appear in EU cosmetic annex entries. Some substances have both, some have only one, and some older entries may have neither.

The INCI Checker accepts ingredient names, CAS numbers and EC numbers. Check this CAS number directly, then verify the result against supplier specification sheets and every linked annex condition.

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Tools & next steps

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