What does the restriction note for TOLUENE-2,5-DIAMINE SULFATE mean?

The restriction field for TOLUENE-2,5-DIAMINE SULFATE reads: III/9a. This is the restriction note from the CosIng inventory. For authoritative conditions and limits, always refer to the linked annex entries.

What other records share CAS 615-50-9?

CAS 615-50-9 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains TOLUENE-2,5-DIAMINE SULFATE?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 3863615/10/2010

TOLUENE-2,5-DIAMINE SULFATE

2-Methyl-p-phenylenediamine sulphate (CI 76042)

TOLUENE-2,5-DIAMINE SULFATE is linked to 1 EU annex record on this page. Inventory note: III/9a.

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Regulatory evidence by market

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Market	Evidence status	Records	Source language
European Union	Evidence linked Restricted entry found Open this evidence	1	English and EU languages
Great Britain	Source mapped Official source mapped; ingredient rule not imported	0	English
Canada	Source mapped Official source mapped; ingredient rule not imported	0	English and French
New Zealand	Evidence linked Restricted Open this evidence	1	English
ASEAN	Source mapped Official source mapped; ingredient rule not imported	0	English and national languages
China	Source mapped Official source mapped; ingredient rule not imported	0	Chinese with selected English material
Japan	Source mapped Official source mapped; ingredient rule not imported	0	Japanese; official English translation available
South Korea	Evidence linked Prohibited + Restricted Open this evidence	2	Korean with some English names
United States	Source mapped Official source mapped; ingredient rule not imported	0	English
Australia	Source mapped Official source mapped; ingredient rule not imported	0	English
Brazil	Source mapped Official source mapped; ingredient rule not imported	0	Portuguese with INCI crosswalks
India	Source mapped Official source mapped; ingredient rule not imported	0	English and Hindi
Saudi Arabia	Source mapped Official source mapped; ingredient rule not imported	0	Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 615-50-9

CAS 615-50-9PubChem CID 22856

2,5-Diaminotoluene sulfate

2,5-diaminotoluene sulfate is an organic sulfate salt obtained by combining 2,5-diaminotoluene with one molar equivalent of sulfuric acid; occurs as an intermediate during hair dye formulation. It has a role as an allergen. It is a diamine and an organic sulfate salt. It is functionally related to a 2-methyl-1,4-phenylenediamine. — ChEBI

IUPAC name: 2-methylbenzene-1,4-diamine;sulfuric acid

Molecular formula: C7H12N2O4S
Molecular weight: 220.25 g/mol
Exact mass: 220.05177804 Da
Topological polar surface area: 135.0 Å²
Hydrogen-bond donors: 4
Hydrogen-bond acceptors: 6
Covalent units: 2
Defined stereocentres: 0

Also known as

Fouramine STDToluene-2,5-diamine sulfateC.I. Oxidation Base 4p-Toluylenediamine sulfate2-Methyl-1,4-benzenediamine sulfateCI Oxidation Base 4Toluene-2,5-diamine, sulfateRodol BLFX

16 more reported names

para-Toluenediamine sulphateNCI-C01832CI 76043para-Toluylenediamine sulphateC.I. 76043Toluylene-2,5-diamine sulphatep-Toluenediamine sulphate2,5-TDSp-Tolylenediamine sulphatep-Toluylenediamine sulphate2,5-Diaminotoluene sulphate8PSD05SPE22-Methyl-para-phenylenediamine sulphateToluene-2,5-diamine, sulfate (1:1)JAROCOL TDSCHEBI:156544

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:156544

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for TOLUENE-2,5-DIAMINE SULFATE

INCI name

TOLUENE-2,5-DIAMINE SULFATE

Description

2-Methyl-p-phenylenediamine sulphate (CI 76042)

Record provenance

Inventory reference: 38636
Imported identity: TOLUENE-2,5-DIAMINE SULFATE
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for TOLUENE-2,5-DIAMINE SULFATE

Annex III Restriction reference

Entry 9a

Toluene-2,5-diamine Toluene-2,5-diamine sulphate

CAS: 95-70-5 / 615-50-9

EC: 202-442-1 / 210-431-8

Key data

CAS

615-50-9

210-431-8

Restriction

III/9a

Function

HAIR DYEING: Imparting color to hair. Hair dyeing preparations may be temporary, semi-permanent, or permanent, depending on the length of time the colorant remains on the hair.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#28958 · TOLUENE-2,5-DIAMINE SULFATE

The markets do not agree about this substance: it is prohibited in some and permitted under conditions in others, across the 3 markets that hold a rule for it.

prohibited: South Korea
restricted: European Union New Zealand

South Korea holds more than one rule for this substance, so its position there depends on the use.

See every substance the markets disagree about

Ingredients with overlapping formulation functions

TETRABROMOPHENOL BLUEHAIR DYEING

TETRAHYDRO-6-NITROQUINOXALINEHAIR DYEING, LIGHT STABILIZER

THYMOLDENATURANT, FRAGRANCE, HAIR DYEING

TOLUENE-2,5-DIAMINEHAIR DYEING

TOLUENE-2,6-DIAMINEHAIR DYEING

TOLUENE-3,4-DIAMINEHAIR DYEING

ULTRAMARINESHAIR DYEING

VITEX NEGUNDO FLOWER/LEAF/SEED OILANTI-SEBUM, ANTIOXIDANT, HAIR DYEING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How TOLUENE-2,5-DIAMINE SULFATE appears in the CosIng inventory

The CosIng inventory lists TOLUENE-2,5-DIAMINE SULFATE as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.

TOLUENE-2,5-DIAMINE SULFATE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

TOLUENE-2,5-DIAMINE SULFATE appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

The restriction field for TOLUENE-2,5-DIAMINE SULFATE reads: "III/9a". This is the restriction note recorded in the CosIng inventory for this ingredient. For authoritative conditions and limits, always refer to the linked annex entries above.

According to the EU CosIng inventory, TOLUENE-2,5-DIAMINE SULFATE carries the following function designation(s):

HAIR DYEING

CAS 615-50-9 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for TOLUENE-2,5-DIAMINE SULFATE

This page combines the CosIng inventory entry for TOLUENE-2,5-DIAMINE SULFATE with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research TOLUENE-2,5-DIAMINE SULFATE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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