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Annex III Entry 9a 02/09/2022

Toluene-2,5-diamine Toluene-2,5-diamine sulphate

Toluene-2,5-diamine Toluene-2,5-diamine sulphate is listed in Annex III and may only be used under the conditions shown in this record.

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Restricted substance— Annex III, EU Regulation 1223/2009
Entry: 9a

Record details

Product type

Products intended for colouring eyelashes

Other restrictions

(a) (i) General use
(a) (ii) Professional use

(b) Professional use

For (a) and (b): After mixing under oxidative conditions the maximum concentration applied to hair or eyelashes must not exceed 2,0 % (cal­culated as free base) or 3,6 % (calculated as sulfate salt)

Warnings

(a) To be printed on the label:
The mixing ratio.
' Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16.
Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if:
— you have a rash on your face or sensitive, irritated and damaged scalp,
— you have ever experienced any reaction after colouring your hair,
— you have experienced a reaction to a temporary “black henna” tattoo in the past.

Contains phenylenediamines (toluenediamines)

(a) (i) Do not use to dye eyelashes.
(a) (ii) Wear suitable gloves. For professional use only.’

(b) As from 3 March 2018, to be printed on the label: The mixing ratio.
' This product can cause severe allergic reactions. Read and follow instructions.

This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase the risk of allergy.

Eyelashes shall not be coloured if the consumer:
— has a rash on the face or sensitive, irritated and damaged scalp,
— has experienced any reaction after colouring hair or eyelashes,
— has experienced a reaction to a temporary “black henna” tattoo in the past.

Rinse eyes immediately if product comes into contact with them.

Contains phenylenediamines (toluenediamines).

Wear suitable gloves.

For professional use only’.

Chemical name

Toluene-2,5-diamine Toluene-2,5-diamine sulphate

Chemical / IUPAC name

1,4-Benzenediamine, 2-methyl- 2,5-Diaminotoluene sulphate

Regulatory information

Regulation

(EC) 2013/1197

SCCS opinions

Identified ingredients

Key data

CAS
95-70-5 / 615-50-9
EC
202-442-1 / 210-431-8
Annex
III
Entry number
9a

Inventory links for Toluene-2,5-diamine Toluene-2,5-diamine sulphate

Annex III 22
Shared product type

RESORCINOL

CAS: 108-46-3
EC: 203-585-2
Annex III 272
Shared product type

P-AMINOPHENOL

CAS: 123-30-8
EC: 204-616-2

What Annex III means for Toluene-2,5-diamine Toluene-2,5-diamine sulphate

Toluene-2,5-diamine Toluene-2,5-diamine sulphate is a restricted substance under Annex III of EU Cosmetics Regulation 1223/2009. Its use in cosmetics is only permitted under the specific conditions set out in the entry above, including applicable concentration limits, product type restrictions and required warning statements.

When including this substance in a formulation, all conditions — maximum concentration, product scope and warning labels — must be met simultaneously. Compliance with one condition does not override the others.

This record is linked to 2 CosIng inventory ingredients for name and identifier cross-reference. The page also surfaces 12 related annex records with overlapping identifiers, annex logic or naming patterns.

Compliance checklist

  • Confirm product type compatibility: (a) Products intended for colouring eyelashes (b) Products intended for colouring eyelashes
  • Include required warning statement on product label.
  • Document conditions of use in the Product Information File (PIF).

Frequently asked questions

Toluene-2,5-diamine Toluene-2,5-diamine sulphate is listed in Annex III of EU Regulation 1223/2009 as a restricted substance. It may only be used under the conditions specified in the entry, including any maximum concentration, product type limitation and required warning statements shown above.

CAS 95-70-5 / 615-50-9 is the unique numerical identifier assigned to Toluene-2,5-diamine Toluene-2,5-diamine sulphate by the Chemical Abstracts Service. In cosmetic compliance work, the CAS number is used to cross-reference the substance across regulatory databases, raw material specifications and safety assessment reports. Multiple EU annex entries may share the same CAS number if the same substance appears under different conditions or in different annexes.

Use the INCI Checker tool on this site to paste your full ingredient list (INCI) and scan it against all Annex II–VI entries. The tool highlights any ingredients that match restricted, prohibited or allergen-flagged records. This is useful for rapid compliance screening of finished product formulas or raw material declarations.
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Source note for Annex III record Toluene-2,5-diamine Toluene-2,5-diamine sulphate

This page summarizes one Annex III record for Toluene-2,5-diamine Toluene-2,5-diamine sulphate from public European Commission cosmetic materials and adds linked inventory or identifier matches when available.

Use this record page to review Annex III conditions for Toluene-2,5-diamine Toluene-2,5-diamine sulphate, but confirm any final regulatory decision against the current official annex wording and source files.

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