Skip to main content
CosIng Checker
CosIng Checker
EU cosmetic ingredients, restrictions and safety
Login
InventoryRef 6022728/07/2020

TETRABROMOPHENOL BLUE

Phenol, 4,4'-(4,5,6,7-Tetrabromo-1,1-Dioxido-3H-2,1-Benzoxathiol-3-ylidene)Bis[2,6-Dibromo-

TETRABROMOPHENOL BLUE is linked to 1 EU annex record on this page.

INCI CheckerCompare all markets Search similar

Regulatory evidence by market

This matrix separates verified ingredient rules from sources that are mapped but not yet imported. No imported rule does not mean the ingredient is permitted.

Compare markets

Swipe or scroll horizontally to see every column.

MarketEvidence statusRecordsSource language
European UnionEvidence linked
Restricted entry found
Open this evidence		1English and EU languages
Great BritainEvidence linked
Restricted
Open this evidence		1English
CanadaSource mapped
Official source mapped; ingredient rule not imported
0English and French
New ZealandEvidence linked
Restricted
Open this evidence		1English
ASEANEvidence linked
Restricted
Open this evidence		1English and national languages
ChinaSource mapped
Official source mapped; ingredient rule not imported
0Chinese with selected English material
JapanSource mapped
Official source mapped; ingredient rule not imported
0Japanese; official English translation available
South KoreaSource mapped
Official source mapped; ingredient rule not imported
0Korean with some English names
United StatesSource mapped
Official source mapped; ingredient rule not imported
0English
AustraliaSource mapped
Official source mapped; ingredient rule not imported
0English
BrazilSource mapped
Official source mapped; ingredient rule not imported
0Portuguese with INCI crosswalks
IndiaEvidence linked
Restricted
Open this evidence		1English and Hindi
Saudi ArabiaEvidence linked
Restricted
Open this evidence		1Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 4430-25-5
CAS 4430-25-5PubChem CID 78159

Tetrabromophenol blue

Tetrabromophenol blue is a member of benzofurans. — ChEBI

IUPAC name
2,6-dibromo-4-[4,5,6,7-tetrabromo-3-(3,5-dibromo-4-hydroxyphenyl)-1,1-dioxo-2,1lambda6-benzoxathiol-3-yl]phenol
Molecular formula
C19H6Br8O5S
Molecular weight
985.5 g/mol
Exact mass
985.33210 Da
XLogP3
8.8
Topological polar surface area
92.2 Ų
Hydrogen-bond donors
2
Hydrogen-bond acceptors
5
Covalent units
1
Defined stereocentres
0

Also known as

4,5,6,7-Tetrabromo-3,3-bis(3,5-dibromo-4-hydroxyphenyl)-3H-benzo[c][1,2]oxathiole 1,1-dioxideTetrabromphenol tetrabromsulfonphthaleinPhenol,4,4'-(4,5,6,7-tetrabromo-1,1-dioxido-3H-2,1-benzoxathiol-3-ylidene)bis[2,6-dibromo-S6FO6931N7NSC-11236Phenol, 4,4'-(4,5,6,7-tetrabromo-1,1-dioxido-3H-2,1-benzoxathiol-3-ylidene)bis(2,6-dibromo-Phenol, 4,4'-(4,5,6,7-tetrabromo-1,1-dioxido-3H-2,1-benzoxathiol-3-ylidene)bis[2,6-dibromo-Tetrabromophenoltetrabromosulfophthalein
16 more reported names
4,4'-(4,5,6,7-Tetrabromo-3H-2,1-benzoxathiol-3-ylidene)bis(2,6-dibromophenol) S,S-dioxide4,5,6,7-Tetrabromo-3,3-bis(3,5-dibromo-4-hydroxy-phenyl)-3H-benzo[c][1,2]oxathiole 1,1-dioxideC19H6Br8O5So-Toluenesulfonic acid,4,5,6-tetrabromo-.alpha.,.alpha.-bis(3,5-dibromo-4-hydroxyphenyl)-.alpha.-hydroxy-Tetrabromophenol blue, INDTetrabromphenolblau3,3-bis(3,5-dibromo-4-hydroxyphenyl)-4,5,6,7-tetrabromobenzo[c]1,2-oxathiolene -1,1-dioneTetrabromophenyl blueCHEBI:176933QPMIVFWZGPTDPN-UHFFFAOYSA-NTXB-00027HY-W140928Benzenesulfonic acid, 2-(bis(3,5-dibromo-4-hydroxyphenyl)hydroxymethyl)-3,4,5,6-tetrabromo-BS-44190Tetrabromophenol Blue, Dye content 85 %Tetrabromophenol blue pound TBPB pound(c)
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for TETRABROMOPHENOL BLUE

INCI name

TETRABROMOPHENOL BLUE

Description

Phenol, 4,4'-(4,5,6,7-Tetrabromo-1,1-Dioxido-3H-2,1-Benzoxathiol-3-ylidene)Bis[2,6-Dibromo-

Record provenance

Inventory reference
60227
Imported identity
TETRABROMOPHENOL BLUE
Source update
28/07/2020
European Commission CosIng source notes

Key data

CAS
4430-25-5
EC
224-622-9
Restriction
—
Function
HAIR DYEING
Imparting color to hair. Hair dyeing preparations may be temporary, semi-permanent, or permanent, depending on the length of time the colorant remains on the hair.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#28520 · TETRABROMOPHENOL BLUE

Ingredients with overlapping formulation functions

SOLVENT YELLOW 44HAIR DYEING
SOLVENT YELLOW 85HAIR DYEING
TAMARIX GALLICA GALL POWDERHAIR CONDITIONING; HAIR DYEING
TETRAAMINOPYRIMIDINE SULFATEHAIR DYEING
TETRAHYDRO-6-NITROQUINOXALINEHAIR DYEING, LIGHT STABILIZER
THYMOLDENATURANT, FRAGRANCE, HAIR DYEING
TOLUENE-2,5-DIAMINEHAIR DYEING
TOLUENE-2,5-DIAMINE SULFATEHAIR DYEING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicalsPubChem PUG RESTEU Safety Gate cosmetic product alertsECHA CHEMUS EPA CompToxCosmetic Ingredient Review safety assessmentsFDA Global Substance Registration SystemILO/WHO International Chemical Safety CardsJapan NITE-CHRIPNIOSH Pocket Guide to Chemical HazardsOECD eChemPortal

How TETRABROMOPHENOL BLUE appears in the CosIng inventory

The CosIng inventory lists TETRABROMOPHENOL BLUE as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.

TETRABROMOPHENOL BLUE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

TETRABROMOPHENOL BLUE appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

According to the EU CosIng inventory, TETRABROMOPHENOL BLUE carries the following function designation(s):

CAS 4430-25-5 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.
View CAS records

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.
Open INCI Checker

Source note for TETRABROMOPHENOL BLUE

This page combines the CosIng inventory entry for TETRABROMOPHENOL BLUE with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research TETRABROMOPHENOL BLUE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

View sourcesView updates

Tools & next steps

Check your formula

Scan a full INCI list to detect TETRABROMOPHENOL BLUE and any linked EU annex restrictions or allergen flags.

INCI Checker

Search similar ingredients

Find other inventory ingredients and annex entries related to TETRABROMOPHENOL BLUE, its identifiers or nearby name variants.

Search