What does the restriction note for 2-AMINO-4-HYDROXYETHYLAMINOANISOLE SULFATE mean?

The restriction field for 2-AMINO-4-HYDROXYETHYLAMINOANISOLE SULFATE reads: III/245. This is the restriction note from the CosIng inventory. For authoritative conditions and limits, always refer to the linked annex entries.

What other records share CAS 83763-48-8?

CAS 83763-48-8 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains 2-AMINO-4-HYDROXYETHYLAMINOANISOLE SULFATE?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 3148813/10/2015

2-AMINO-4-HYDROXYETHYLAMINOANISOLE SULFATE

(3-ammonio-4-methoxyphenyl)(2-hydroxyethyl)ammonium sulphate

2-AMINO-4-HYDROXYETHYLAMINOANISOLE SULFATE is linked to 1 EU annex record on this page. Inventory note: III/245.

INCI Checker Compare all markets Search similar

Regulatory evidence by market

This matrix separates verified ingredient rules from sources that are mapped but not yet imported. No imported rule does not mean the ingredient is permitted.

Compare markets

Swipe or scroll horizontally to see every column.

Market	Evidence status	Records	Source language
European Union	Evidence linked Restricted entry found Open this evidence	1	English and EU languages
Great Britain	Source mapped Official source mapped; ingredient rule not imported	0	English
Canada	Source mapped Official source mapped; ingredient rule not imported	0	English and French
New Zealand	Evidence linked Restricted Open this evidence	1	English
ASEAN	Source mapped Official source mapped; ingredient rule not imported	0	English and national languages
China	Source mapped Official source mapped; ingredient rule not imported	0	Chinese with selected English material
Japan	Source mapped Official source mapped; ingredient rule not imported	0	Japanese; official English translation available
South Korea	Source mapped Official source mapped; ingredient rule not imported	0	Korean with some English names
United States	Source mapped Official source mapped; ingredient rule not imported	0	English
Australia	Source mapped Official source mapped; ingredient rule not imported	0	English
Brazil	Source mapped Official source mapped; ingredient rule not imported	0	Portuguese with INCI crosswalks
India	Source mapped Official source mapped; ingredient rule not imported	0	English and Hindi
Saudi Arabia	Source mapped Official source mapped; ingredient rule not imported	0	Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 83763-48-8

CAS 83763-48-8PubChem CID 14453744

2-Amino-4-((2-hydroxyethyl)amino)anisole sulfate

The CIR Expert Panel concluded that 2-amino-4-hydroxyethylaminoanisole and 2-amino-4-hydroxyethylaminoanisole sulfate are safe for use in oxidative hair dye formulations. Were the free base (2-amino-4-hydroxyethylaminoanisole) to be used in the future, the expectation is that it would be used at concentrations similar to the sulfate salt. The Expert Panel cautions that these ingredients should not be used in hair dye products in which N-nitroso compounds may be formed. — Cosmetic Ingredient Review (CIR)

IUPAC name: 2-(3-amino-4-methoxyanilino)ethanol;sulfuric acid

Molecular formula: C9H16N2O6S
Molecular weight: 280.30 g/mol
Exact mass: 280.07290741 Da
Topological polar surface area: 150.0 Å²
Hydrogen-bond donors: 5
Hydrogen-bond acceptors: 8
Covalent units: 2
Defined stereocentres: 0

Also known as

2-Amino-4-hydroxyethylaminoanisole sulfatejarocol ahea2-((3-Amino-4-methoxyphenyl)amino)ethanol sulfateCOVASTYLE AHEAS2-Amino-4-[(2-hydroxyethyl)amino]anisole SulfateUM91A54Z8GETHANOL, 2-((3-AMINO-4-METHOXYPHENYL)AMINO)-, SULFATE (1:1)ETHANOL, 2-((3-AMINO-4-METHOXYPHENYL)AMINO)-, SULFATE (1:1) (SALT)

16 more reported names

RefChem:85206280-734-85-(2-Hydroxyethylamino)-2-methoxylaniline sulfate2-Amino-4-hydroxyethylamino anisole sulfateC9H16N2O6SAC-82942-[(3-amino-4-methoxyphenyl)amino]ethan-1-ol; sulfuric acidCS-01505762-((3-Amino-4-methoxyphenyl)amino)ethanol sulfate;2-Amino-4-hydroxyethylaminoanisole sulfate2-[(3-amino-4-methoxyphenyl)amino]ethan-1-ol2-AMINO-4-HYDROXYETHYLAMINOANISOLESULFATEGWHLYFOWAINYAH-UHFFFAOYSA-NDS-0791DB-0204322-(3-amino-4-methoxy-anilino)ethanol;sulfuric acid2-((3-amino-4-methoxyphenyl)amino)ethan-1-ol sulfate

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

EPA DTXSID:DTXSID30892455

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for 2-AMINO-4-HYDROXYETHYLAMINOANISOLE SULFATE

INCI name

2-AMINO-4-HYDROXYETHYLAMINOANISOLE SULFATE

Description

(3-ammonio-4-methoxyphenyl)(2-hydroxyethyl)ammonium sulphate

Record provenance

Inventory reference: 31488
Imported identity: 2-AMINO-4-HYDROXYETHYLAMINOANISOLE SULFATE
Source update: 13/10/2015

European Commission CosIng source notes

Annex records for 2-AMINO-4-HYDROXYETHYLAMINOANISOLE SULFATE

Annex III Restriction reference

Entry 245

2-AMINO-4-HYDROXYETHYLAMINOANISOLE / 2-AMINO-4-HYDROXYETHYLAMINOANISOLE SULFATE

CAS: 83763-47-7 / 83763-48-8

EC: 280-733-2 / 280-734-8

Key data

CAS

83763-48-8

280-734-8

Restriction

III/245

Function

HAIR DYEING: Imparting color to hair. Hair dyeing preparations may be temporary, semi-permanent, or permanent, depending on the length of time the colorant remains on the hair.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#190 · 2-AMINO-4-HYDROXYETHYLAMINOANISOLE SULFATE

Ingredients with overlapping formulation functions

2-(2,2-DIMETHOXY)ETHOXY-P-PHENYLENEDIAMINEHAIR DYEING

2-AMINO-3-HYDROXYPYRIDINEHAIR DYEING

2-AMINO-3-NITROPHENOLHAIR DYEING

2-AMINO-4-HYDROXYETHYLAMINOANISOLEHAIR DYEING

2-AMINO-4-NITROPHENOLHAIR DYEING

2-AMINO-4-NITROPHENOL SULFATEHAIR DYEING

2-AMINO-5-ETHYLPHENOL HCLHAIR DYEING

2-AMINO-5-NITROPHENOLHAIR DYEING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How 2-AMINO-4-HYDROXYETHYLAMINOANISOLE SULFATE appears in the CosIng inventory

The CosIng inventory lists 2-AMINO-4-HYDROXYETHYLAMINOANISOLE SULFATE as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.

2-AMINO-4-HYDROXYETHYLAMINOANISOLE SULFATE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

2-AMINO-4-HYDROXYETHYLAMINOANISOLE SULFATE appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

The restriction field for 2-AMINO-4-HYDROXYETHYLAMINOANISOLE SULFATE reads: "III/245". This is the restriction note recorded in the CosIng inventory for this ingredient. For authoritative conditions and limits, always refer to the linked annex entries above.

According to the EU CosIng inventory, 2-AMINO-4-HYDROXYETHYLAMINOANISOLE SULFATE carries the following function designation(s):

HAIR DYEING

CAS 83763-48-8 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

View CAS records

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

Open INCI Checker

Source note for 2-AMINO-4-HYDROXYETHYLAMINOANISOLE SULFATE

This page combines the CosIng inventory entry for 2-AMINO-4-HYDROXYETHYLAMINOANISOLE SULFATE with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research 2-AMINO-4-HYDROXYETHYLAMINOANISOLE SULFATE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

View sources View updates

Tools & next steps

Check your formula

Scan a full INCI list to detect 2-AMINO-4-HYDROXYETHYLAMINOANISOLE SULFATE and any linked EU annex restrictions or allergen flags.

INCI Checker

Search similar ingredients

Find other inventory ingredients and annex entries related to 2-AMINO-4-HYDROXYETHYLAMINOANISOLE SULFATE, its identifiers or nearby name variants.