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Annex III Entry 217 14/02/2014

M-AMINOPHENOL; M-AMINOPHENOL HCL; M-AMINOPHENOL SULFATE

m-Aminophenol and its salts

M-AMINOPHENOL; M-AMINOPHENOL HCL; M-AMINOPHENOL SULFATE is listed in Annex III and may only be used under the conditions shown in this record.

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Restricted substance— Annex III, EU Regulation 1223/2009
Entry: 217

Chemical identity and properties

PubChem 2D chemical structure for CAS 38171-54-9
CAS 38171-54-9PubChem CID 23669774

phenol, 3-amino-, sodium salt

IUPAC name
sodium 3-aminophenolate
Molecular formula
C6H6NNaO
Molecular weight
131.11 g/mol
Exact mass
131.03470810 Da
Topological polar surface area
49.1 Ų
Hydrogen-bond donors
1
Hydrogen-bond acceptors
2
Covalent units
2
Defined stereocentres
0

Also known as

m-Aminophenol sodium3-Aminophenol sodiumm-Aminofenolate sodnym-Aminofenolate sodny [Czech]RefChem:369169sodium m-aminophenolatesodium m-aminophenoxidesodium meta-aminophenolate
1 more reported name
VLDROEPDJWRSGR-UHFFFAOYSA-M
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 51-81-0
CAS 51-81-0PubChem CID 12231984

3-Aminophenol hydrochloride

IUPAC name
3-aminophenol;hydrochloride
Molecular formula
C6H8ClNO
Molecular weight
145.59 g/mol
Exact mass
145.0294416 Da
Topological polar surface area
46.3 Ų
Hydrogen-bond donors
3
Hydrogen-bond acceptors
2
Covalent units
2
Defined stereocentres
0

Also known as

m-Aminophenol HClRefChem:92987200-125-2NQM2XX7XPOPhenol, 3-amino-, hydrochloridem-aminophenol hydrochloride3-aminophenol,hydrochlorideBS-52111
8 more reported names
(3-hydroxyphenyl)azanium;chloridePhenol, 3-amino-, hydrochloride (1:1)3-AMINOPHENOLHYDROCHLORIDEFT-06920723-AMINOPHENOLHYDROCHLORIDDCBCSMXGLXAXDM-UHFFFAOYSA-N3-Aminophenol--hydrogen chloride (1/1)Phenol, 3-aamino-a, hydrochloride (1:1)
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 591-27-5
CAS 591-27-5PubChem CID 11568

3-Aminophenol

3-aminophenol is an aminophenol that is one of three amino derivatives of phenol which has the single amino substituent located meta to the phenolic -OH group. — ChEBI

IUPAC name
3-aminophenol
Molecular formula
C6H7NO
Molecular weight
109.13 g/mol
Exact mass
109.052763847 Da
XLogP3
0.2
Topological polar surface area
46.3 Ų
Hydrogen-bond donors
2
Hydrogen-bond acceptors
2
Covalent units
1
Defined stereocentres
0

Also known as

M-AMINOPHENOL3-Hydroxyanilinem-HydroxyanilinePhenol, 3-amino-1-Amino-3-hydroxybenzeneFouramine EGFutramine EGFourrine EG
16 more reported names
m-HydroxyaminobenzenePelagol EGTertral EGFurro EGRenal EGUrsol EG3-Amino-1-hydroxybenzeneFourrine 65Zoba EGNako TEGm-HydroxyphenylaminePhenol, m-amino-BASF ursol EGm-AminofenolC.I. Oxidation Base 7CI Oxidation Base 7
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 68239-81-6
CAS 68239-81-6PubChem CID 163205

m-Aminophenol sulfate

IUPAC name
bis(3-aminophenol);sulfuric acid
Molecular formula
C12H16N2O6S
Molecular weight
316.33 g/mol
Exact mass
316.07290741 Da
Topological polar surface area
175.0 Ų
Hydrogen-bond donors
6
Hydrogen-bond acceptors
8
Covalent units
3
Defined stereocentres
0

Also known as

3-Aminophenol sulfate (2:1)Phenol, 3-amino-, sulfate (2:1) (salt)3-Aminophenol, hemisulfateZ0PXZ6XHUYEINECS 269-475-1Phenol, 3-amino-, sulfate (2:1)Bis((3-hydroxyphenyl)ammonium) sulphateBIS[(3-HYDROXYPHENYL)AMMONIUM] SULPHATE
12 more reported names
RefChem:800342M-AMINOPHENOL SULFATE [INCI]COLOREX MAPSRODOL EGS3-aminophenol;sulfuric acidbis(3-aminophenol); sulfuric acid3-Aminophenol sulfateUNII-Z0PXZ6XHUYm-aminophenolsulfateTVBNHNUPRXSKHS-UHFFFAOYSA-NSulfuric acid--3-aminophenol (1/2)AS-58600
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Record details

Product type

Hair dye substance in oxidative hair dye products Products intended for colouring eyelashes

Other restrictions

For (a) and (b): After mixing under oxidative conditions the maximum concentration applied to hair or eyelashes must not exceed 1,2 %
(b) For professional use only

Warnings

(a) To be printed on the label: The mixing ratio. “ Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase your risk of allergy.Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary ‘black henna’ tattoo in the past.”
(b) To be printed on the label: The mixing ratio. “For professional use only. This product can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase the risk of allergy. Eyelashes shall not be coloured if the consumer: — has a rash on the face or sensitive, irritated and damaged scalp, — has experienced any reaction after colouring hair or eyelashes,— has experienced a reaction to a temporary ‘black henna’ tattoo in the past. Rinse eyes immediately if product comes into contact with them.”

INCI glossary name

M-AMINOPHENOL; M-AMINOPHENOL HCL; M-AMINOPHENOL SULFATE

Chemical name

m-Aminophenol and its salts

Regulatory information

Regulation

(EC) 2013/1197

See every entry this act set

SCCS opinions

Identified ingredients

Key data

CAS
591-27-5/ 51-81-0 / 68239-81-6 /38171-54-9
EC
209-711-2 / 200-125-2 / 269-475-1
Annex
III
Entry number
217

Inventory links for M-AMINOPHENOL; M-AMINOPHENOL HCL; M-AMINOPHENOL SULFATE

Inventory Restriction reference
Ref 35147

M-AMINOPHENOL

CAS: 591-27-5
EC: 209-711-2
Annex III 16
Shared product type

1-NAPHTHOL

CAS: 90-15-3
EC: 201-969-4
Annex III 16
Shared product type

1-Naphthol

CAS: 90-15-3
EC: 201-969-4
Annex III 193
Shared product type

ACID RED 52

CAS: 3520-42-1
EC: 222-529-8

What Annex III means for M-AMINOPHENOL; M-AMINOPHENOL HCL; M-AMINOPHENOL SULFATE

M-AMINOPHENOL; M-AMINOPHENOL HCL; M-AMINOPHENOL SULFATE is a restricted substance under Annex III of EU Cosmetics Regulation 1223/2009. Its use in cosmetics is only permitted under the specific conditions set out in the entry above, including applicable concentration limits, product type restrictions and required warning statements.

When including this substance in a formulation, all conditions — maximum concentration, product scope and warning labels — must be met simultaneously. Compliance with one condition does not override the others.

This record is linked to 3 CosIng inventory ingredients for name and identifier cross-reference. The page also surfaces 12 related annex records with overlapping identifiers, annex logic or naming patterns.

Compliance checklist

  • Confirm product type compatibility: (a) Hair dye substance in oxidative hair dye products (b) Products intended for colouring eyelashes
  • Include required warning statement on product label.
  • Document conditions of use in the Product Information File (PIF).

Frequently asked questions

M-AMINOPHENOL; M-AMINOPHENOL HCL; M-AMINOPHENOL SULFATE is listed in Annex III of EU Regulation 1223/2009 as a restricted substance. It may only be used under the conditions specified in the entry, including any maximum concentration, product type limitation and required warning statements shown above.

CAS 591-27-5/ 51-81-0 / 68239-81-6 /38171-54-9 is the unique numerical identifier assigned to M-AMINOPHENOL; M-AMINOPHENOL HCL; M-AMINOPHENOL SULFATE by the Chemical Abstracts Service. In cosmetic compliance work, the CAS number is used to cross-reference the substance across regulatory databases, raw material specifications and safety assessment reports. Multiple EU annex entries may share the same CAS number if the same substance appears under different conditions or in different annexes.

Use the INCI Checker tool on this site to paste your full ingredient list (INCI) and scan it against all Annex II–VI entries. The tool highlights any ingredients that match restricted, prohibited or allergen-flagged records. This is useful for rapid compliance screening of finished product formulas or raw material declarations.
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Source note for Annex III record M-AMINOPHENOL; M-AMINOPHENOL HCL; M-AMINOPHENOL SULFATE

This page summarizes one Annex III record for M-AMINOPHENOL; M-AMINOPHENOL HCL; M-AMINOPHENOL SULFATE from public European Commission cosmetic materials and adds linked inventory or identifier matches when available.

Use this record page to review Annex III conditions for M-AMINOPHENOL; M-AMINOPHENOL HCL; M-AMINOPHENOL SULFATE, but confirm any final regulatory decision against the current official annex wording and source files.

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