Annex III Entry 317 24/11/2020

HC Orange No. 6

Di-[2-[(E)-2-[4-[bis(2-hydroxyethyl)aminophenyl]vinyl]pyridin-1-ium]-ethyl]disulphide dimethanesulfonate

HC Orange No. 6 is listed in Annex III and may only be used under the conditions shown in this record. Maximum concentration in this record: As from 3 June 2021: 0,5 %.

Restricted substance— Annex III, EU Regulation 1223/2009
Max conc.: As from 3 June 2021: 0,5 %
Entry: 317

Record details

Maximum concentration

As from 3 June 2021: 0,5 %

Other restrictions

Methanesulfonates impurities, in particular ethyl methanesulfonate shall not be present.

INCI glossary name

HC Orange No. 6

Chemical name

Di-[2-[(E)-2-[4-[bis(2-hydroxyethyl)aminophenyl]vinyl]pyridin-1-ium]-ethyl]disulphide dimethanesulfonate

Chemical / IUPAC name

Di-[2-[(E)-2-[4-[bis(2-hydroxyethyl)aminophenyl]vinyl]pyridin-1-ium]-ethyl]disulphide dimethanesulfonate

Regulatory information

Regulation

(EU) 2020/1683

Identified ingredients

Key data

EC
Annex
Entry number
317

Inventory links for HC Orange No. 6

Annex III 190
Shared product type

ACID BLUE 9

CAS: 3844-45-9 - 2650-18-2 - 68921-42-6
EC: 223-339-8 - 220-168-0 - 272-939-6
Annex III 191
Shared product type

CURRY RED

CAS: 25956-17-6
EC: 247-368-0
Annex III 192
Shared product type

ACID RED 18

CAS: 2611-82-7 - 12227-64-4
EC: 220-036-2 - 235-438-3
Annex III 193
Shared product type

ACID RED 52

CAS: 3520-42-1
EC: 222-529-8
Annex III 195
Shared product type

ACID BLUE 62

CAS: 4368-56-3
EC: 224-460-9
Annex III 204
Shared product type

DIHYDROXYINDOLINE

CAS: 29539-03-5 - 138937-28-7
EC: - - 421-170-6

What Annex III means for HC Orange No. 6

HC Orange No. 6 is a restricted substance under Annex III of EU Cosmetics Regulation 1223/2009. Its use in cosmetics is only permitted under the specific conditions set out in the entry above, including applicable concentration limits, product type restrictions and required warning statements.

When including this substance in a formulation, all conditions — maximum concentration, product scope and warning labels — must be met simultaneously. Compliance with one condition does not override the others.

This record is linked to 1 CosIng inventory ingredient for name and identifier cross-reference. The page also surfaces 12 related annex records with overlapping identifiers, annex logic or naming patterns.

Compliance checklist

  • Ensure formulation concentration does not exceed: As from 3 June 2021: 0,5 %
  • Confirm product type compatibility: Hair dye substance in non-oxidative hair dye products
  • Document conditions of use in the Product Information File (PIF).

Frequently asked questions

HC Orange No. 6 is listed in Annex III of EU Regulation 1223/2009 as a restricted substance. It may only be used under the conditions specified in the entry, including any maximum concentration, product type limitation and required warning statements shown above.

CAS 1449653-83-1 is the unique numerical identifier assigned to HC Orange No. 6 by the Chemical Abstracts Service. In cosmetic compliance work, the CAS number is used to cross-reference the substance across regulatory databases, raw material specifications and safety assessment reports. Multiple EU annex entries may share the same CAS number if the same substance appears under different conditions or in different annexes.

The maximum concentration of As from 3 June 2021: 0,5 % applies to the concentration of the substance in the ready-to-use cosmetic product. When the substance is supplied as part of a blend or mixture, the calculation must account for the contribution of all sources in the formulation. The combined concentration must not exceed the stated limit.

Use the INCI Checker tool on this site to paste your full ingredient list (INCI) and scan it against all Annex II–VI entries. The tool highlights any ingredients that match restricted, prohibited or allergen-flagged records. This is useful for rapid compliance screening of finished product formulas or raw material declarations.

Source note for Annex III record HC Orange No. 6

This page summarizes one Annex III record for HC Orange No. 6 from public European Commission cosmetic materials and adds linked inventory or identifier matches when available.

Use this record page to review Annex III conditions for HC Orange No. 6, but confirm any final regulatory decision against the current official annex wording and source files.

Tools & next steps

Check your formula

Paste a full INCI list to detect HC Orange No. 6 and other flagged EU annex records in one pass.

INCI Checker

Compare entries

Compare HC Orange No. 6 side by side with another annex record to review differences in restrictions, concentrations and annex placement.

Compare

Browse the annex

See all records in Annex III and compare regulatory conditions across substances in this annex.

Open Annex III