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Annex III Entry 189 13/08/2020

CI 19140 / ACID YELLOW 23

Trisodium 5-hydroxy-1-(4-sulphophenyl)-4-(4-sulphophenylazo)pyrazole-3-carboxylate and aluminium lake (see note 17). CI 19140

CI 19140 / ACID YELLOW 23 is listed in Annex III and may only be used under the conditions shown in this record. Maximum concentration in this record: 0.5%.

Restricted substance— Annex III, EU Regulation 1223/2009
Max conc.: 0.5%
Entry: 189

Chemical identity and properties

PubChem 2D chemical structure for CAS 12225-21-7
CAS 12225-21-7PubChem CID 22833487

C.I. Pigment Yellow 100

C.I. Pigment Yellow 100 is an organonitrogen compound and an organooxygen compound. It is functionally related to an alpha-amino acid. ChEBI

IUPAC name
aluminum tris(4-[[3-carboxy-5-oxo-1-(4-sulfophenyl)-4H-pyrazol-4-yl]diazenyl]benzenesulfonate)
Molecular formula
C48H33AlN12O27S6
Molecular weight
1429.2 g/mol
Exact mass
1427.9717743 Da
Topological polar surface area
669.0 Ų
Hydrogen-bond donors
6
Hydrogen-bond acceptors
36
Covalent units
4
Defined stereocentres
0

Also known as

YELLOW LAKE TRefChem:572571JAPAN YELLOW 4 ALUMINUM LAKEFD AND C YELLOW NO. 5 ALUMINUM LAKE4,5-DIHYDRO-5-OXO-1-(4-SULFOPHENYL)-4-((4-SULFOPHENYL)AZO)-1H-PYRAZOLE-3-CARBOXYLIC ACID ALUMINUM COMPLEXaluminum;4-[[3-carboxy-5-oxo-1-(4-sulfophenyl)-4H-pyrazol-4-yl]diazenyl]benzenesulfonateCHEBI:189920CID 22833487
2 more reported names
aluminum;4-[[3-carboxy-5-oxo-1-(4-sulophenyl)-4H-pyrazol-4-yl]diazenyl]benzenesulonateAluminium tris(4-{[3-carboxy-5-oxo-1-(4-sulfophenyl)-4,5-dihydro-1H-pyrazol-4-yl]diazenyl}benzene-1-sulfonate)
External database identifiers

Evidence from additional scientific databases

NIH PubChem PUG-View
Exact identifier match22833487

Attributed physical-property, hazard, environmental and use annotations.

  • Solubility: less than 1 mg/mL at 70 °F (NTP, 1992) Source: CAMEO Chemicals
  • First Aid: EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.; SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.; INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) shou Source: CAMEO Chemicals
  • Note: This chemical does not meet GHS hazard criteria for 100% (503 of 503) of all reports. Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: Not Classified; Reported as not meeting GHS hazard criteria by 503 of 503 companies. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 503 reports by companies from 1 notifications to the ECHA C&L Inventory.; Reported as not meeting GHS hazard criteria per 503 of 503 reports by companies.; There are 0 notifications provided by 0 of 503 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 1934-21-0
CAS 1934-21-0PubChem CID 164825

Tartrazine

Tartrazine is an organic sodium salt which is the trisodium salt of tartrazine acid. A synthetic lemon yellow azo dye used as a food colouring. It has a role as a histological dye and a food colouring. It contains a tartrazine(3-). ChEBI

IUPAC name
trisodium;5-oxo-1-(4-sulfonatophenyl)-4-[(4-sulfonatophenyl)diazenyl]-4H-pyrazole-3-carboxylate
Molecular formula
C16H9N4Na3O9S2
Molecular weight
534.4 g/mol
Exact mass
533.95040307 Da
Topological polar surface area
229.0 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
12
Covalent units
4
Defined stereocentres
0

Also known as

Yellow 5Food Yellow 4Aizen tartrazineTartraphenineTartran YellowAmacid Yellow TCilefa Yellow T1342-47-8
16 more reported names
FD&C Yellow No. 5A.F. Yellow No. 4FD & C Yellow no. 5C.I. 19140Tartrazine FD&C Yellow #5Atul TartrazineErio TartrazineKako TartrazineTartrazine LakeTartrazine BTartrazine CTartrazine GTartrazine MTartrazine NTartrazine OTartrazine T
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Record details

Maximum concentration

0.5%

INCI glossary name

CI 19140 / ACID YELLOW 23

Chemical name

Trisodium 5-hydroxy-1-(4-sulphophenyl)-4-(4-sulphophenylazo)pyrazole-3-carboxylate and aluminium lake (see note 17). CI 19140

Chemical / IUPAC name

Trisodium 5-hydroxy-1-(4-sulphophenyl)-4-(4-sulphophenylazo)pyrazole-3-carboxylate and aluminium lake; CI 19140

Regulatory information

Regulation

(EC) 2013/344

See every entry this act set

SCCS opinions

  • Opinion on Acid Yellow 23

Key data

CAS
1934-21-0 - 12225-21-7
EC
217-699-5 - 235-428-9
Annex
Entry number
189

Inventory links for CI 19140 / ACID YELLOW 23

Inventory Restriction reference
Ref 31637

ACID YELLOW 23

CAS: 1934-21-0
EC: 217-699-5
Inventory Restriction reference
Ref 32737

CI 19140

CAS: 1934-21-0
EC: 217-699-5
Annex IV 44
Shared CAS number

CI 19140

CAS: 12225-21-7; 1934-21-0
EC: 235-428-9; 217-699-5
Annex III 190
Shared product type

ACID BLUE 9

CAS: 3844-45-9 - 2650-18-2 - 68921-42-6
EC: 223-339-8 - 220-168-0 - 272-939-6
Annex III 191
Shared product type

CURRY RED

CAS: 25956-17-6
EC: 247-368-0
Annex III 192
Shared product type

ACID RED 18

CAS: 2611-82-7 - 12227-64-4
EC: 220-036-2 - 235-438-3
Annex III 193
Shared product type

ACID RED 52

CAS: 3520-42-1
EC: 222-529-8
Annex III 195
Shared product type

ACID BLUE 62

CAS: 4368-56-3
EC: 224-460-9
Annex III 204
Shared product type

DIHYDROXYINDOLINE

CAS: 29539-03-5 - 138937-28-7
EC: - - 421-170-6

What Annex III means for CI 19140 / ACID YELLOW 23

CI 19140 / ACID YELLOW 23 is a restricted substance under Annex III of EU Cosmetics Regulation 1223/2009. Its use in cosmetics is only permitted under the specific conditions set out in the entry above, including applicable concentration limits, product type restrictions and required warning statements.

When including this substance in a formulation, all conditions — maximum concentration, product scope and warning labels — must be met simultaneously. Compliance with one condition does not override the others.

This record is linked to 3 CosIng inventory ingredients for name and identifier cross-reference. The page also surfaces 12 related annex records with overlapping identifiers, annex logic or naming patterns.

Compliance checklist

  • Ensure formulation concentration does not exceed: 0.5%
  • Confirm product type compatibility: Hair dye substance in non-oxidative hair dye products
  • Document conditions of use in the Product Information File (PIF).

Frequently asked questions

CI 19140 / ACID YELLOW 23 is listed in Annex III of EU Regulation 1223/2009 as a restricted substance. It may only be used under the conditions specified in the entry, including any maximum concentration, product type limitation and required warning statements shown above.

CAS 1934-21-0 - 12225-21-7 is the unique numerical identifier assigned to CI 19140 / ACID YELLOW 23 by the Chemical Abstracts Service. In cosmetic compliance work, the CAS number is used to cross-reference the substance across regulatory databases, raw material specifications and safety assessment reports. Multiple EU annex entries may share the same CAS number if the same substance appears under different conditions or in different annexes.

The maximum concentration of 0.5% applies to the concentration of the substance in the ready-to-use cosmetic product. When the substance is supplied as part of a blend or mixture, the calculation must account for the contribution of all sources in the formulation. The combined concentration must not exceed the stated limit.

Use the INCI Checker tool on this site to paste your full ingredient list (INCI) and scan it against all Annex II–VI entries. The tool highlights any ingredients that match restricted, prohibited or allergen-flagged records. This is useful for rapid compliance screening of finished product formulas or raw material declarations.

Source note for Annex III record CI 19140 / ACID YELLOW 23

This page summarizes one Annex III record for CI 19140 / ACID YELLOW 23 from public European Commission cosmetic materials and adds linked inventory or identifier matches when available.

Use this record page to review Annex III conditions for CI 19140 / ACID YELLOW 23, but confirm any final regulatory decision against the current official annex wording and source files.

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