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Annex III Entry 192 14/08/2020

ACID RED 18

Trisodium 1-(1-naphthylazo)-2-hydroxynaphthalene-4',6,8-trisulphonate and aluminium lake (Cl 16255) (see note 17).

ACID RED 18 is listed in Annex III and may only be used under the conditions shown in this record. Maximum concentration in this record: 0.5%.

Restricted substance— Annex III, EU Regulation 1223/2009
Max conc.: 0.5%
Entry: 192

Chemical identity and properties

PubChem 2D chemical structure for CAS 12227-64-4
CAS 12227-64-4PubChem CID 136086322

Ponceau 4R aluminum

IUPAC name
aluminum 7-hydroxy-8-[(4-sulfonatonaphthalen-1-yl)diazenyl]naphthalene-1,3-disulfonate
Molecular formula
C20H11AlN2O10S3
Molecular weight
562.5 g/mol
Exact mass
561.9391215 Da
Topological polar surface area
242.0 Ų
Hydrogen-bond donors
1
Hydrogen-bond acceptors
12
Covalent units
2
Defined stereocentres
0

Also known as

K6DSC8J075C.I. Food Red 7:1EINECS 235-438-3C.I. FOOD RED 7 ALUMINUM LAKEC.I. 16255:1RefChem:867236Aluminum, 7-hydroxy-8-(4-sulfo-1-naphthalenyl)azo-1,3-naphthalenedisulfonato(3-)-235-438-3
5 more reported names
Aluminum, (7-hydroxy-8-((4-sulfo-1-naphthalenyl)azo)-1,3-naphthalenedisulfonato(3-))-Aluminum, [7-hydroxy-8-[(4-sulfo-1-naphthalenyl)azo]-1,3-naphthalenedisulfonato(3-)]-UNII-K6DSC8J07511652 Dispersed RedC.I.Food Red 7:1

Evidence from additional scientific databases

NIH PubChem PUG-View
Exact identifier match136086322

Attributed physical-property, hazard, environmental and use annotations.

  • Note: This chemical does not meet GHS hazard criteria for 100% (5 of 5) of all reports. Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: Not Classified; Reported as not meeting GHS hazard criteria by 5 of 5 companies. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 5 reports by companies from 1 notifications to the ECHA C&L Inventory.; Reported as not meeting GHS hazard criteria per 5 of 5 reports by companies.; There are 0 notifications provided by 0 of 5 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 2611-82-7
CAS 2611-82-7PubChem CID 17466

C.I. Acid Red 18, trisodium salt

IUPAC name
trisodium;7-hydroxy-8-[(4-sulfonatonaphthalen-1-yl)diazenyl]naphthalene-1,3-disulfonate
Molecular formula
C20H11N2Na3O10S3
Molecular weight
604.5 g/mol
Exact mass
603.92689092 Da
Topological polar surface area
242.0 Ų
Hydrogen-bond donors
1
Hydrogen-bond acceptors
12
Covalent units
4
Defined stereocentres
0

Also known as

RefChem:1080550Ponceau 4RNew coccineAcid red 18C.I. Acid Red 18Food Red No. 102Victoria Scarlet 3RSX Purple
16 more reported names
Brilliant Scarlet 4RCoccineColacid Ponceau 4RFood Red 7Acilan Scarlet V3RAcid Brilliant Scarlet 3RCerticol Ponceau 4RSCochineal Red AAtul Acid Scarlet 3RFood Red 102Food Red Number 102C.I. Acid Red 28Edicol Supra Ponceau 4RSNeucoccinBrilliant Ponceau 3RBrilliant Scarlet 3R
External database identifiers

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Record details

Maximum concentration

0.5%

INCI glossary name

ACID RED 18

Chemical name

Trisodium 1-(1-naphthylazo)-2-hydroxynaphthalene-4',6,8-trisulphonate and aluminium lake (Cl 16255) (see note 17).

Chemical / IUPAC name

Trisodium 1-(1-naphthylazo)-2-hydroxynaphthalene-4',6,8-trisulphonate and aluminium lake (Cl 16255)

Regulatory information

Regulation

(EC) 2013/344

See every entry this act set

SCCS opinions

Key data

CAS
2611-82-7 - 12227-64-4
EC
220-036-2 - 235-438-3
Annex
Entry number
192

Inventory links for ACID RED 18

Inventory Restriction reference
Ref 31623

ACID RED 18

CAS: 2611-82-7
EC: 220-036-2
Inventory Restriction reference
Ref 32728

CI 16255

CAS: 2611-82-7
EC: 220-036-2
Annex IV 35
Shared CAS number

CI 16255

CAS: 2611-82-7
EC: 220-036-2
Annex III 190
Shared product type

ACID BLUE 9

CAS: 3844-45-9 - 2650-18-2 - 68921-42-6
EC: 223-339-8 - 220-168-0 - 272-939-6
Annex III 191
Shared product type

CURRY RED

CAS: 25956-17-6
EC: 247-368-0
Annex III 193
Shared product type

ACID RED 52

CAS: 3520-42-1
EC: 222-529-8
Annex III 195
Shared product type

ACID BLUE 62

CAS: 4368-56-3
EC: 224-460-9
Annex III 204
Shared product type

DIHYDROXYINDOLINE

CAS: 29539-03-5 - 138937-28-7
EC: - - 421-170-6

What Annex III means for ACID RED 18

ACID RED 18 is a restricted substance under Annex III of EU Cosmetics Regulation 1223/2009. Its use in cosmetics is only permitted under the specific conditions set out in the entry above, including applicable concentration limits, product type restrictions and required warning statements.

When including this substance in a formulation, all conditions — maximum concentration, product scope and warning labels — must be met simultaneously. Compliance with one condition does not override the others.

This record is linked to 3 CosIng inventory ingredients for name and identifier cross-reference. The page also surfaces 12 related annex records with overlapping identifiers, annex logic or naming patterns.

Compliance checklist

  • Ensure formulation concentration does not exceed: 0.5%
  • Confirm product type compatibility: Hair dye substance in non-oxidative hair dye products
  • Document conditions of use in the Product Information File (PIF).

Frequently asked questions

ACID RED 18 is listed in Annex III of EU Regulation 1223/2009 as a restricted substance. It may only be used under the conditions specified in the entry, including any maximum concentration, product type limitation and required warning statements shown above.

CAS 2611-82-7 - 12227-64-4 is the unique numerical identifier assigned to ACID RED 18 by the Chemical Abstracts Service. In cosmetic compliance work, the CAS number is used to cross-reference the substance across regulatory databases, raw material specifications and safety assessment reports. Multiple EU annex entries may share the same CAS number if the same substance appears under different conditions or in different annexes.

The maximum concentration of 0.5% applies to the concentration of the substance in the ready-to-use cosmetic product. When the substance is supplied as part of a blend or mixture, the calculation must account for the contribution of all sources in the formulation. The combined concentration must not exceed the stated limit.

Use the INCI Checker tool on this site to paste your full ingredient list (INCI) and scan it against all Annex II–VI entries. The tool highlights any ingredients that match restricted, prohibited or allergen-flagged records. This is useful for rapid compliance screening of finished product formulas or raw material declarations.

Source note for Annex III record ACID RED 18

This page summarizes one Annex III record for ACID RED 18 from public European Commission cosmetic materials and adds linked inventory or identifier matches when available.

Use this record page to review Annex III conditions for ACID RED 18, but confirm any final regulatory decision against the current official annex wording and source files.

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