HC Red No 1
2-Nitro-N1-phenyl-benzene-1,4- diamine
HC Red No 1 is listed in Annex III and may only be used under the conditions shown in this record. Maximum concentration in this record: 1,0%.
Chemical identity and properties
4-Amino-2-nitrodiphenylamine
On the basis of the animal and clinical data included in this report, the CIR Expert Panel concludes that HC Red No. 1 is safe as used in hair dye formulations at concentrations of ≤ 0.5%. The CIR Expert Panel re-affirmed the above conclusion June 2011. — Cosmetic Ingredient Review (CIR)
- IUPAC name
- 2-nitro-1-N-phenylbenzene-1,4-diamine
- Molecular formula
- C12H11N3O2
- Molecular weight
- 229.23 g/mol
- Exact mass
- 229.085126602 Da
- XLogP3
- 3.0
- Topological polar surface area
- 83.9 Ų
- Hydrogen-bond donors
- 2
- Hydrogen-bond acceptors
- 4
- Covalent units
- 1
- Defined stereocentres
- 0
Also known as
15 more reported names
External database identifiers
- EPA DTXSID:DTXSID4062640
Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
Record details
Maximum concentration
1,0%
Warnings
Hair colorants can cause severe allergic reactions.
INCI glossary name
HC Red No 1
Chemical name
2-Nitro-N1-phenyl-benzene-1,4- diamine
Chemical / IUPAC name
2-Nitro-N1-phenyl-benzene-1,4- diamine
Regulatory information
Key data
Inventory links for HC Red No 1
Related records for HC Red No 1
CI 19140 / ACID YELLOW 23
ACID BLUE 9
6-METHOXY-2-METHYLAMINO-3-AMINOPYRIDINE HCL
What Annex III means for HC Red No 1
HC Red No 1 is a restricted substance under Annex III of EU Cosmetics Regulation 1223/2009. Its use in cosmetics is only permitted under the specific conditions set out in the entry above, including applicable concentration limits, product type restrictions and required warning statements.
When including this substance in a formulation, all conditions — maximum concentration, product scope and warning labels — must be met simultaneously. Compliance with one condition does not override the others.
This record is linked to 1 CosIng inventory ingredient for name and identifier cross-reference. The page also surfaces 12 related annex records with overlapping identifiers, annex logic or naming patterns.
Compliance checklist
- Ensure formulation concentration does not exceed: 1,0%
- Confirm product type compatibility: Hair dye substance in non-oxidative hair dye products
- Include required warning statement on product label.
- Document conditions of use in the Product Information File (PIF).
Frequently asked questions
Source note for Annex III record HC Red No 1
This page summarizes one Annex III record for HC Red No 1 from public European Commission cosmetic materials and adds linked inventory or identifier matches when available.
Use this record page to review Annex III conditions for HC Red No 1, but confirm any final regulatory decision against the current official annex wording and source files.
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