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Annex III Entry 237 24/07/2013

HC RED NO 13

2,2'-[(4-Amino-3-nitrophenyl)imino]bisethanol hydrochloride and its salts

HC RED NO 13 is listed in Annex III and may only be used under the conditions shown in this record. Maximum concentration in this record: (b) 2.5% (as hydro-chloride).

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Restricted substance— Annex III, EU Regulation 1223/2009
Max conc.: (b) 2.5% (as hydro-chloride)
Entry: 237

Chemical identity and properties

PubChem 2D chemical structure for CAS 29705-39-3
CAS 29705-39-3PubChem CID 147315

Ethanol, 2,2'-[(4-amino-3-nitrophenyl)imino]bis-

IUPAC name
2-[4-amino-N-(2-hydroxyethyl)-3-nitroanilino]ethanol
Molecular formula
C10H15N3O4
Molecular weight
241.24 g/mol
Exact mass
241.10625597 Da
XLogP3
0.0
Topological polar surface area
116.0 Ų
Hydrogen-bond donors
3
Hydrogen-bond acceptors
6
Covalent units
1
Defined stereocentres
0

Also known as

2,2'-((4-Amino-3-nitrophenyl)imino)bisethanol2,2'-[(4-Amino-3-nitrophenyl)imino]bisethanolEthanol, 2,2'-((4-amino-3-nitrophenyl)imino)bis-RefChem:591980VOLCMGPDRGNUGR-UHFFFAOYSA-NDB-0681502,2'-[(4-Amino-3-nitrophenyl)imino]diethanol2,2'-[(4-Amino-3-nitrophenyl)azanediyl]di(ethan-1-ol)
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 94158-13-1
CAS 94158-13-1PubChem CID 21909552

HC Red no. 13

IUPAC name
2-[4-amino-N-(2-hydroxyethyl)-3-nitroanilino]ethanol;hydrochloride
Molecular formula
C10H16ClN3O4
Molecular weight
277.70 g/mol
Exact mass
277.0829337 Da
Topological polar surface area
116.0 Ų
Hydrogen-bond donors
4
Hydrogen-bond acceptors
6
Covalent units
2
Defined stereocentres
0

Also known as

2,2'-[(4-Amino-3-nitrophenyl)imino]bisethanol hydrochlorideHC RED 13jarocol red 133S057K0K0BCOLOREX HCR13EINECS 303-083-42,2'-((4-Amino-3-nitrophenyl)imino)bisethanol hydrochlorideEthanol, 2,2'-((4-amino-3-nitrophenyl)imino)bis-, monohydrochloride
16 more reported names
Ethanol, 2,2'-[(4-amino-3-nitrophenyl)imino]bis-, monohydrochlorideRefChem:783435HC RED NO. 13 [INCI]303-083-42,2'-((4-Amino-3-nitrophenyl)azanediyl)diethanol hydrochloride2,2'-((4-amino-3-nitrophenyl)azanediyl)bis(ethan-1-ol) hydrochloridehcredC10H16ClN3O4UNII-3S057K0K0BASAQRGCLIPUSEK-UHFFFAOYSA-N1-amino-2-nitro-4-bis-(2'-hydroxyethyl)aminobenzene hydrochloridehcredno.13,2,2'-[(4-amino-3-nitrophenyl)imino]bisethanolhydrochloride,DB-0574762-[4-amino-N-(2-hydroxyethyl)-3-nitroanilino]ethanol hydrochloride2-[4-amino-N-(2-hydroxyethyl)-3-nitroanilino]ethanol,hydrochloride2-[(4-azanyl-3-nitro-phenyl)-(2-hydroxyethyl)amino]ethanol;hydrochloride
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Record details

Maximum concentration

(b) 2.5% (as hydro-chloride)

Product type

Hair dye substance in oxidative hair dye products Hair due substance in non-oxidative hair dye products

Other restrictions

a) After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 1.25% (as hydrochloride)

Warnings

Hair colourants can cause seere allergic reactions
Read and follow instructions

INCI glossary name

HC RED NO 13

Chemical name

2,2'-[(4-Amino-3-nitrophenyl)imino]bisethanol hydrochloride and its salts

Regulatory information

Regulation

(EC) 2013/344

See every entry this act set

SCCS opinions

Identified ingredients

Key data

CAS
29705-39-3 - 94158-13-1
EC
-- 303-083-4
Annex
III
Entry number
237

Inventory links for HC RED NO 13

Inventory Restriction reference
Ref 34207

HC RED NO. 13

CAS: 94158-13-1
EC: 303-083-4
Annex III 16
Shared product type

1-NAPHTHOL

CAS: 90-15-3
EC: 201-969-4
Annex III 16
Shared product type

1-Naphthol

CAS: 90-15-3
EC: 201-969-4
Annex III 193
Shared product type

ACID RED 52

CAS: 3520-42-1
EC: 222-529-8

What Annex III means for HC RED NO 13

HC RED NO 13 is a restricted substance under Annex III of EU Cosmetics Regulation 1223/2009. Its use in cosmetics is only permitted under the specific conditions set out in the entry above, including applicable concentration limits, product type restrictions and required warning statements.

When including this substance in a formulation, all conditions — maximum concentration, product scope and warning labels — must be met simultaneously. Compliance with one condition does not override the others.

This record is linked to 1 CosIng inventory ingredient for name and identifier cross-reference. The page also surfaces 12 related annex records with overlapping identifiers, annex logic or naming patterns.

Compliance checklist

  • Ensure formulation concentration does not exceed: (b) 2.5% (as hydro-chloride)
  • Confirm product type compatibility: (a) Hair due substance in oxidative hair dye products (b) Hair due substance in non-oxidative hair dye products
  • Include required warning statement on product label.
  • Document conditions of use in the Product Information File (PIF).

Frequently asked questions

HC RED NO 13 is listed in Annex III of EU Regulation 1223/2009 as a restricted substance. It may only be used under the conditions specified in the entry, including any maximum concentration, product type limitation and required warning statements shown above.

CAS 29705-39-3 - 94158-13-1 is the unique numerical identifier assigned to HC RED NO 13 by the Chemical Abstracts Service. In cosmetic compliance work, the CAS number is used to cross-reference the substance across regulatory databases, raw material specifications and safety assessment reports. Multiple EU annex entries may share the same CAS number if the same substance appears under different conditions or in different annexes.

The maximum concentration of (b) 2.5% (as hydro-chloride) applies to the concentration of the substance in the ready-to-use cosmetic product. When the substance is supplied as part of a blend or mixture, the calculation must account for the contribution of all sources in the formulation. The combined concentration must not exceed the stated limit.

Use the INCI Checker tool on this site to paste your full ingredient list (INCI) and scan it against all Annex II–VI entries. The tool highlights any ingredients that match restricted, prohibited or allergen-flagged records. This is useful for rapid compliance screening of finished product formulas or raw material declarations.
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Source note for Annex III record HC RED NO 13

This page summarizes one Annex III record for HC RED NO 13 from public European Commission cosmetic materials and adds linked inventory or identifier matches when available.

Use this record page to review Annex III conditions for HC RED NO 13, but confirm any final regulatory decision against the current official annex wording and source files.

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