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Annex II Entry 1759 15/01/2026

Sodium 3-(allyloxy)-2-hydroxypropanesulphonate

Sodium 3-(allyloxy)-2-hydroxypropanesulphonate is listed in Annex II as a prohibited substance for cosmetic products placed on the EU market.

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Prohibited substance— Annex II, EU Regulation 1223/2009
Entry: 1759

Chemical identity and properties

PubChem 2D chemical structure for CAS 52556-42-0
CAS 52556-42-0PubChem CID 23677323

Sodium 3-(allyloxy)-2-hydroxypropanesulphonate

IUPAC name
sodium 2-hydroxy-3-prop-2-enoxypropane-1-sulfonate
Molecular formula
C6H11NaO5S
Molecular weight
218.21 g/mol
Exact mass
218.02248890 Da
Topological polar surface area
95.0 Ų
Hydrogen-bond donors
1
Hydrogen-bond acceptors
5
Covalent units
2
Defined stereocentres
0

Also known as

UNII-G49391UTKD1-Propanesulfonic acid, 2-hydroxy-3-(2-propenyloxy)-, monosodium saltEINECS 258-004-5Sodium 3-allyloxy-2-hydroxy-1-propanesulfonateCOPS IEC 258-004-5SODIUM 2-HYDROXY-3-(2-PROPENYLOXY)-1-PROPANESULFONATERefChem:183660
16 more reported names
sodium 3-(allyloxy)-2-hydroxypropane-1-sulfonateSodium 3-(allyloxy)-2-hydroxypropane-1-sulfonate(40 wt. % in H2O)sodium;2-hydroxy-3-prop-2-enoxypropane-1-sulfonate1-Propanesulfonic acid, 2-hydroxy-3-(2-propen-1-yloxy)-, sodium salt (1:1)3-ALLYLOXY-2-HYDROXY-1-PROPANESULFONIC ACID, SODIUM SALTCJGJYOBXQLCLRG-UHFFFAOYSA-MTox21_202569CAS-52556-42-0Sodium 1-allyloxy-2 hydroxypropyl sulfonateCS-0157969sodium 3-allyloxy-2-hydroxy-propanesulfonatesodium;2-oxidanyl-3-prop-2-enoxy-propane-1-sulfonate3-allyloxy-2-hydroxy-1-propanesulfonic acid sodium saltSodium 2-hydroxy-3-[(prop-2-en-1-yl)oxy]propane-1-sulfonateSodium3-(allyloxy)-2-hydroxypropane-1-sulfonate(40wt.%inH2O)Sodium 3-allyloxy-2-hydroxypropane-1-sulfonate, 40% aqueous solution
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External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Record details

Chemical name

Sodium 3-(allyloxy)-2-hydroxypropanesulphonate

Regulatory information

Regulation

(EU) 2026/78

See every entry this act set

Key data

CAS
52556-42-0
EC
258-004-5
Annex
II
Entry number
1759

Direct matches are limited for this record, so nearby entries from Annex II are shown as well.

Annex II 1754
Nearby record in the same annex

Acetone oxime

CAS: 127-06-0
EC: 204-820-1
Annex II 1764
Nearby record in the same annex

Trimethyl borate

CAS: 121-43-7
EC: 204-468-9

What Annex II means for Sodium 3-(allyloxy)-2-hydroxypropanesulphonate

Sodium 3-(allyloxy)-2-hydroxypropanesulphonate is listed as a prohibited substance under Annex II of EU Cosmetics Regulation 1223/2009 and must not be intentionally added. Article 17 separately addresses unintended small quantities that are technically unavoidable under good manufacturing practice and compatible with the Article 3 safety requirement.

Formulators must screen their ingredients and raw materials to ensure none contain this substance. Suppliers should provide documentation confirming absence when requested.

The page also surfaces 12 related annex records with overlapping identifiers, annex logic or naming patterns.

Compliance checklist

  • Verify this substance is absent from all raw materials and finished formulations.
  • Request absence confirmation or CoA from raw material suppliers.
  • Document the screening result in the Product Information File (PIF).

Frequently asked questions

Yes. Sodium 3-(allyloxy)-2-hydroxypropanesulphonate is listed in Annex II of EU Cosmetics Regulation 1223/2009 and is prohibited as an intentionally added cosmetic ingredient. Article 17 provides a narrow exception for unintended small quantities that are technically unavoidable under good manufacturing practice, provided the product remains safe under Article 3.

CAS 52556-42-0 is the unique numerical identifier assigned to Sodium 3-(allyloxy)-2-hydroxypropanesulphonate by the Chemical Abstracts Service. In cosmetic compliance work, the CAS number is used to cross-reference the substance across regulatory databases, raw material specifications and safety assessment reports. Multiple EU annex entries may share the same CAS number if the same substance appears under different conditions or in different annexes.

Use the INCI Checker tool on this site to paste your full ingredient list (INCI) and scan it against all Annex II–VI entries. The tool highlights any ingredients that match restricted, prohibited or allergen-flagged records. This is useful for rapid compliance screening of finished product formulas or raw material declarations.
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Source note for Annex II record Sodium 3-(allyloxy)-2-hydroxypropanesulphonate

This page summarizes one Annex II record for Sodium 3-(allyloxy)-2-hydroxypropanesulphonate from public European Commission cosmetic materials and adds linked inventory or identifier matches when available.

Use this record page to review Annex II conditions for Sodium 3-(allyloxy)-2-hydroxypropanesulphonate, but confirm any final regulatory decision against the current official annex wording and source files.

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