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Annex II Entry 1723 24/08/2023

Pendimethalin (ISO); N-(1-ethylpropyl)-2,6-dinitro-3,4-xylidene

Pendimethalin (ISO); N-(1-ethylpropyl)-2,6-dinitro-3,4-xylidene is listed in Annex II as a prohibited substance for cosmetic products placed on the EU market.

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Prohibited substance— Annex II, EU Regulation 1223/2009
Entry: 1723

Chemical identity and properties

PubChem 2D chemical structure for CAS 40487-42-1
CAS 40487-42-1PubChem CID 38479

Pendimethalin

Pendimethalin is a member of the class of substituted anilines that is N-(pentan-3-yl)aniline bearing two additional nitro substituents at positions 2 and 6 as well as two methyl substituents at positions 3 and 4. A herbicide used to control most annual grasses and many annual broad-leaved weeds. It has a role as a herbicide, an agrochemical and an environmental contaminant. It is a C-nitro compound, a substituted aniline and a secondary amino compound. — ChEBI

IUPAC name
3,4-dimethyl-2,6-dinitro-N-pentan-3-ylaniline
Molecular formula
C13H19N3O4
Molecular weight
281.31 g/mol
Exact mass
281.13755610 Da
XLogP3
5.2
Topological polar surface area
104.0 Ų
Hydrogen-bond donors
1
Hydrogen-bond acceptors
5
Covalent units
1
Defined stereocentres
0

Also known as

PendimethalinePenoxalineProwlPhenoxalinHerbadoxAccotabStompPenoxyn
16 more reported names
Sipaxol3,4-Dimethyl-2,6-dinitro-N-(pentan-3-yl)anilineWay UpTendimethalinGo-Go-SanWayupSWGCN-(1-Ethylpropyl)-2,6-dinitro-3,4-xylidineStomp 330DStomp 330EN-(1-Ethylpropyl)-3,4-dimethyl-2,6-dinitrobenzenamineSouthern Weed Grass ControlCaswell No. 454BB3,4-Dimethyl-2,6-dinitro-N-(1-ethylpropyl)anilineAC 92553N-(1-Ethylpropyl)-3,4-dimethyl-2,6-dinitroaniline
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Record details

Chemical name

Pendimethalin (ISO); N-(1-ethylpropyl)-2,6-dinitro-3,4-xylidene

Regulatory information

Regulation

(EU) 2023/1490

See every entry this act set

Key data

CAS
40487-42-1
EC
254-938-2
Annex
II
Entry number
1723

Direct matches are limited for this record, so nearby entries from Annex II are shown as well.

Annex II 1717
Nearby record in the same annex

Cumene

CAS: 98-82-8
EC: 202-704-5

What Annex II means for Pendimethalin (ISO); N-(1-ethylpropyl)-2,6-dinitro-3,4-xylidene

Pendimethalin (ISO); N-(1-ethylpropyl)-2,6-dinitro-3,4-xylidene is listed as a prohibited substance under Annex II of EU Cosmetics Regulation 1223/2009 and must not be intentionally added. Article 17 separately addresses unintended small quantities that are technically unavoidable under good manufacturing practice and compatible with the Article 3 safety requirement.

Formulators must screen their ingredients and raw materials to ensure none contain this substance. Suppliers should provide documentation confirming absence when requested.

The page also surfaces 12 related annex records with overlapping identifiers, annex logic or naming patterns.

Compliance checklist

  • Verify this substance is absent from all raw materials and finished formulations.
  • Request absence confirmation or CoA from raw material suppliers.
  • Document the screening result in the Product Information File (PIF).

Frequently asked questions

Yes. Pendimethalin (ISO); N-(1-ethylpropyl)-2,6-dinitro-3,4-xylidene is listed in Annex II of EU Cosmetics Regulation 1223/2009 and is prohibited as an intentionally added cosmetic ingredient. Article 17 provides a narrow exception for unintended small quantities that are technically unavoidable under good manufacturing practice, provided the product remains safe under Article 3.

CAS 40487-42-1 is the unique numerical identifier assigned to Pendimethalin (ISO); N-(1-ethylpropyl)-2,6-dinitro-3,4-xylidene by the Chemical Abstracts Service. In cosmetic compliance work, the CAS number is used to cross-reference the substance across regulatory databases, raw material specifications and safety assessment reports. Multiple EU annex entries may share the same CAS number if the same substance appears under different conditions or in different annexes.

Use the INCI Checker tool on this site to paste your full ingredient list (INCI) and scan it against all Annex II–VI entries. The tool highlights any ingredients that match restricted, prohibited or allergen-flagged records. This is useful for rapid compliance screening of finished product formulas or raw material declarations.
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Source note for Annex II record Pendimethalin (ISO); N-(1-ethylpropyl)-2,6-dinitro-3,4-xylidene

This page summarizes one Annex II record for Pendimethalin (ISO); N-(1-ethylpropyl)-2,6-dinitro-3,4-xylidene from public European Commission cosmetic materials and adds linked inventory or identifier matches when available.

Use this record page to review Annex II conditions for Pendimethalin (ISO); N-(1-ethylpropyl)-2,6-dinitro-3,4-xylidene, but confirm any final regulatory decision against the current official annex wording and source files.

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