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Annex II Entry 1726 04/06/2024

Copper (nano) [INCI] Colloidal Copper (nano) [INCI]

Copper (nano) [INCI] Colloidal Copper (nano) [INCI] is listed in Annex II as a prohibited substance for cosmetic products placed on the EU market.

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Prohibited substance— Annex II, EU Regulation 1223/2009
Entry: 1726

Chemical identity and properties

PubChem 2D chemical structure for CAS 7440-50-8
CAS 7440-50-8PubChem CID 23978

Copper

Copper is a metal that occurs naturally throughout the environment, in rocks, soil, water, and air. Copper is an essential element in plants and animals (including humans), which means it is necessary for us to live. Therefore, plants and animals must absorb some copper from eating, drinking, and breathing. Copper is used to make many different kinds of products like wire, plumbing pipes, and sheet metal. U.S. pennies made before 1982 are made of copper, while those made after 1982 are only coated with copper. Copper is also combined with other metals to make brass and bronze pipes and faucets. Copper compounds are commonly used in agriculture to treat plant diseases like mildew, for water treatment and, as preservatives for wood, leather, and fabrics. — Agency for Toxic Substances and Disease Registry (ATSDR)

IUPAC name
copper
Molecular formula
Cu
Molecular weight
63.55 g/mol
Exact mass
62.929597 Da
Topological polar surface area
0.0 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
0
Covalent units
1
Defined stereocentres
0

Also known as

Copper powdercuprumCopper bronzeBronze powderCopper, elementalTatum-TArwood copperCopper-airborne
16 more reported names
Copper-milledKafar copperParagard T 380aRaney copperGold bronzeAllbri Natural CopperCuprum metallicumCopper slag-milledCopper slag-airbornecuivreCopper M 1CUKupferOFHC CuM1 (Copper)M2 (Copper)
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Record details

Chemical name

Copper (nano) [INCI] Colloidal Copper (nano) [INCI]

Regulatory information

Regulation

(EU) 2024/858

See every entry this act set

SCCS opinions

  • OPINION ON Copper (nano) and Colloidal Copper (nano)

Key data

CAS
7440-50-8
EC
231-159-6
Annex
II
Entry number
1726

Inventory links for Copper (nano) [INCI] Colloidal Copper (nano) [INCI]

Inventory Shared CAS number
Ref 32826

CI 77400

CAS: 7440-50-8
EC: 231-159-6

Direct matches are limited for this record, so nearby entries from Annex II are shown as well.

Annex IV 132
Shared CAS number

CI 77400

CAS: 7440-50-8
EC: 231-159-6

What Annex II means for Copper (nano) [INCI] Colloidal Copper (nano) [INCI]

Copper (nano) [INCI] Colloidal Copper (nano) [INCI] is listed as a prohibited substance under Annex II of EU Cosmetics Regulation 1223/2009 and must not be intentionally added. Article 17 separately addresses unintended small quantities that are technically unavoidable under good manufacturing practice and compatible with the Article 3 safety requirement.

Formulators must screen their ingredients and raw materials to ensure none contain this substance. Suppliers should provide documentation confirming absence when requested.

This record is linked to 1 CosIng inventory ingredient for name and identifier cross-reference. The page also surfaces 12 related annex records with overlapping identifiers, annex logic or naming patterns.

Compliance checklist

  • Verify this substance is absent from all raw materials and finished formulations.
  • Request absence confirmation or CoA from raw material suppliers.
  • Document the screening result in the Product Information File (PIF).

Frequently asked questions

Yes. Copper (nano) [INCI] Colloidal Copper (nano) [INCI] is listed in Annex II of EU Cosmetics Regulation 1223/2009 and is prohibited as an intentionally added cosmetic ingredient. Article 17 provides a narrow exception for unintended small quantities that are technically unavoidable under good manufacturing practice, provided the product remains safe under Article 3.

CAS 7440-50-8 is the unique numerical identifier assigned to Copper (nano) [INCI] Colloidal Copper (nano) [INCI] by the Chemical Abstracts Service. In cosmetic compliance work, the CAS number is used to cross-reference the substance across regulatory databases, raw material specifications and safety assessment reports. Multiple EU annex entries may share the same CAS number if the same substance appears under different conditions or in different annexes.

Use the INCI Checker tool on this site to paste your full ingredient list (INCI) and scan it against all Annex II–VI entries. The tool highlights any ingredients that match restricted, prohibited or allergen-flagged records. This is useful for rapid compliance screening of finished product formulas or raw material declarations.
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Source note for Annex II record Copper (nano) [INCI] Colloidal Copper (nano) [INCI]

This page summarizes one Annex II record for Copper (nano) [INCI] Colloidal Copper (nano) [INCI] from public European Commission cosmetic materials and adds linked inventory or identifier matches when available.

Use this record page to review Annex II conditions for Copper (nano) [INCI] Colloidal Copper (nano) [INCI], but confirm any final regulatory decision against the current official annex wording and source files.

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