Is TRIPEPTIDE-85 safe to use in EU cosmetics?

TRIPEPTIDE-85 is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Always verify against the current official CosIng database before formulating.

What other records share CAS 31461-61-7?

CAS 31461-61-7 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains TRIPEPTIDE-85?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef cosing-live-990022023-05-23

TRIPEPTIDE-85

Tripeptide-85 is the synthetic peptide consisting of glutamine, phenylalanine and valine.

TRIPEPTIDE-85 is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 31461-61-7

CAS 31461-61-7PubChem CID 193678

Glutamyl-valyl-phenylalanine

Glu-Val-Phe is a tripeptide. — ChEBI

IUPAC name: (4S)-4-amino-5-[[(2S)-1-[[(1S)-1-carboxy-2-phenylethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-5-oxopentanoic acid

Molecular formula: C19H27N3O6
Molecular weight: 393.4 g/mol
Exact mass: 393.18998559 Da
XLogP3: -3.2
Topological polar surface area: 159.0 Å²
Hydrogen-bond donors: 5
Hydrogen-bond acceptors: 7
Covalent units: 1
Defined stereocentres: 3

Also known as

Glu-val-pheL-Glutamyl-L-valyl-L-phenylalanineL-Phenylalanine, N-(N-L-alpha-glutamyl-L-valyl)-RefChem:143578H-GLU-VAL-PHE-OH(S)-4-Amino-5-(((S)-1-(((S)-1-carboxy-2-phenylethyl)amino)-3-methyl-1-oxobutan-2-yl)amino)-5-oxopentanoic acidCHEBI:163396FVGOGEGGQLNZGH-DZKIICNBSA-N

6 more reported names

CS-W011720HY-W011004L-alpha-Glutamyl-L-valyl-L-phenylalanineDA-74131(S)-4-Amino-5-(((S)-1-(((S)-1-carboxy-2-phenylethyl)amino)-3-methyl-1-oxobutan-2-yl)amino)-5-oxopentanoicacidN-{2-[(2-Amino-4-carboxy-1-hydroxybutylidene)amino]-1-hydroxy-3-methylbutylidene}phenylalanine

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:163396
EPA DTXSID:DTXSID70953473

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

What the official INCI name states

The official label identifies a peptide- or protein-related cosmetic material.

Identity type from wording: peptide_or_protein

This structure is derived only from the official label wording. It does not establish composition, concentration, chemical equivalence, safety or regulatory permission.

Official European Commission record

CosIng substance ID: 99002
Entry status: Active
Published in the Official Journal: Yes
Recorded by the Commission: 2023-05-23

Open this entry in the official CosIng database

Fields as published by the European Commission. The link opens the entry itself, not a search for it.

Inventory details for TRIPEPTIDE-85

INCI name

TRIPEPTIDE-85

Description

Tripeptide-85 is the synthetic peptide consisting of glutamine, phenylalanine and valine.

Record provenance

Inventory reference: cosing-live-99002
Imported identity: TRIPEPTIDE-85
Source update: 2023-05-23

European Commission CosIng source notes

Annex records for TRIPEPTIDE-85

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Key data

CAS

31461-61-7

—

Restriction

—

Function

DEODORANT: Reducing and/or eliminating unpleasant odour. Contributing against the formation of malodour on body surfaces.
SKIN CONDITIONING - MISCELLANEOUS: Enhancing the appearance of dry and/or damaged skin by reducing flaking and restoring suppleness.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#29414 · TRIPEPTIDE-85

Ingredients with overlapping formulation functions

TRICLOCARBANANTIMICROBIAL, DEODORANT, PRESERVATIVE

TRICLOSANANTIMICROBIAL, DEODORANT, PRESERVATIVE

TRICYCLODECENYL PROPIONATEDEODORANT, FRAGRANCE, PERFUMING

TRIETHOXYSILYLPROPYL STEARDIMONIUM CHLORIDEANTIMICROBIAL, CLEANSING, DEODORANT, SURFACTANT - CLEANSING

TUNGSTEN DISULFIDEABRASIVE, DEODORANT

TUNGSTEN OXIDEABRASIVE, DEODORANT

URGINEA MARITIMA TUBER EXTRACTDEODORANT, FRAGRANCE

USNEA BARBATA EXTRACTDEODORANT

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How TRIPEPTIDE-85 appears in the CosIng inventory

The CosIng inventory lists TRIPEPTIDE-85 as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

TRIPEPTIDE-85 is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

TRIPEPTIDE-85 is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, TRIPEPTIDE-85 carries the following function designation(s):

CAS 31461-61-7 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for TRIPEPTIDE-85

This page reproduces the CosIng inventory entry for TRIPEPTIDE-85 from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research TRIPEPTIDE-85 and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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Tools & next steps

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