What does the restriction note for 2-CHLORO-5-NITRO-N-HYDROXYETHYL P-PHENYLENEDIAMINE mean?

The restriction field for 2-CHLORO-5-NITRO-N-HYDROXYETHYL P-PHENYLENEDIAMINE reads: II/1318. This is the restriction note from the CosIng inventory. For authoritative conditions and limits, always refer to the linked annex entries.

What other records share CAS 50610-28-1?

CAS 50610-28-1 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains 2-CHLORO-5-NITRO-N-HYDROXYETHYL P-PHENYLENEDIAMINE?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef cosing-live-314932024-08-21

2-CHLORO-5-NITRO-N-HYDROXYETHYL P-PHENYLENEDIAMINE

2-CHLORO-5-NITRO-N-HYDROXYETHYL P-PHENYLENEDIAMINE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet. Inventory note: II/1318.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

Markets and their official sources Search every market for this name

Chemical identity and properties

PubChem 2D chemical structure for CAS 50610-28-1

CAS 50610-28-1PubChem CID 5490271

2-((4-Amino-2-chloro-5-nitrophenyl)amino)ethanol

IUPAC name: 2-(4-amino-2-chloro-5-nitroanilino)ethanol

Molecular formula: C8H10ClN3O3
Molecular weight: 231.63 g/mol
Exact mass: 231.0410689 Da
XLogP3: 1.5
Topological polar surface area: 104.0 Å²
Hydrogen-bond donors: 3
Hydrogen-bond acceptors: 5
Covalent units: 1
Defined stereocentres: 0

Also known as

EINECS 256-652-3Ethanol, 2-((4-amino-2-chloro-5-nitrophenyl)amino)-2-[(4-AMINO-2-CHLORO-5-NITROPHENYL)AMINO]ETHANOLEthanol, 2-[(4-amino-2-chloro-5-nitrophenyl)amino]-2-Nitro-5-chloro-N-(2-hydroxyethyl) p-phenylendiamineRefChem:448821Ethanol, 2-(4-amino-2-chloro-5-nitrophenyl)amino-2-Chloro-5-nitro-N-hydroxyethyl p-phenylenediamine

8 more reported names

2-chloro-5-nitro-n-hydroxyethyl-p-phenylenediamine12M0RVW0182-Chloro-5-nitro-n-hydroxyethylp-phenylenediamineUNII-12M0RVW0182-(4-Amino-2-chloro-5-nitroanilino)ethan-1-ol1-Amino-2-Nitro-4-Beta-Hydroxyethylamino-5-Chlorobenzene2-CHLORO-5-NITRO-N-HYDROXYETHYL-1,4-PHENYLENEDIAMINE1-AMINO-2-NITRO-4-(.BETA.-HYDROXYETHYLAMINO)-5-CHLOROBENZENE

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

EPA DTXSID:DTXSID90866157

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Official European Commission record

CosIng substance ID: 31493
Entry status: Active
Published in the Official Journal: Yes
Recorded by the Commission: 2024-08-21

Open this entry in the official CosIng database

Fields as published by the European Commission. The link opens the entry itself, not a search for it.

Inventory details for 2-CHLORO-5-NITRO-N-HYDROXYETHYL P-PHENYLENEDIAMINE

INCI name

2-CHLORO-5-NITRO-N-HYDROXYETHYL P-PHENYLENEDIAMINE

Record provenance

Inventory reference: cosing-live-31493
Imported identity: 2-CHLORO-5-NITRO-N-HYDROXYETHYL P-PHENYLENEDIAMINE
Source update: 2024-08-21

European Commission CosIng source notes

Annex records for 2-CHLORO-5-NITRO-N-HYDROXYETHYL P-PHENYLENEDIAMINE

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Key data

CAS

50610-28-1

256-652-3

Restriction

II/1318

Function

HAIR DYEING: Imparting color to hair. Hair dyeing preparations may be temporary, semi-permanent, or permanent, depending on the length of time the colorant remains on the hair.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#203 · 2-CHLORO-5-NITRO-N-HYDROXYETHYL P-PHENYLENEDIAMINE

Records sharing a CAS or EC identity

2-CHLORO-5-NITRO-N-HYDROXYETHYL-P-PHENYLENEDIAMINE

Ingredients with overlapping formulation functions

2-AMINO-5-ETHYLPHENOL HCLHAIR DYEING

2-AMINO-5-NITROPHENOLHAIR DYEING

2-AMINO-6-CHLORO-4-NITROPHENOLHAIR DYEING

2-AMINOMETHYL-P-AMINOPHENOL HCLHAIR DYEING

2-CHLORO-5-NITRO-N-HYDROXYETHYL-P-PHENYLENEDIAMINEHAIR DYEING

2-CHLORO-6-ETHYLAMINO-4-NITROPHENOLHAIR DYEING

2-CHLORO-P-PHENYLENEDIAMINEHAIR DYEING

2-CHLORO-P-PHENYLENEDIAMINE SULFATEHAIR DYEING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How 2-CHLORO-5-NITRO-N-HYDROXYETHYL P-PHENYLENEDIAMINE appears in the CosIng inventory

The CosIng inventory lists 2-CHLORO-5-NITRO-N-HYDROXYETHYL P-PHENYLENEDIAMINE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

2-CHLORO-5-NITRO-N-HYDROXYETHYL P-PHENYLENEDIAMINE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

2-CHLORO-5-NITRO-N-HYDROXYETHYL P-PHENYLENEDIAMINE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

The restriction field for 2-CHLORO-5-NITRO-N-HYDROXYETHYL P-PHENYLENEDIAMINE reads: "II/1318". This is the restriction note recorded in the CosIng inventory for this ingredient. For authoritative conditions and limits, always refer to the linked annex entries above.

According to the EU CosIng inventory, 2-CHLORO-5-NITRO-N-HYDROXYETHYL P-PHENYLENEDIAMINE carries the following function designation(s):

HAIR DYEING

CAS 50610-28-1 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for 2-CHLORO-5-NITRO-N-HYDROXYETHYL P-PHENYLENEDIAMINE

This page reproduces the CosIng inventory entry for 2-CHLORO-5-NITRO-N-HYDROXYETHYL P-PHENYLENEDIAMINE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research 2-CHLORO-5-NITRO-N-HYDROXYETHYL P-PHENYLENEDIAMINE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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