What other records share CAS 615-66-7?

CAS 615-66-7 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

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InventoryRef 3149516/11/2016

2-CHLORO-P-PHENYLENEDIAMINE

2-chloro-p-phenylenediamine

2-CHLORO-P-PHENYLENEDIAMINE is linked to 1 EU annex record on this page.

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Regulatory evidence by market

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Market	Evidence status	Records	Source language
European Union	Evidence linked Prohibited entry found Open this evidence	1	English and EU languages
Great Britain	Evidence linked Prohibited Open this evidence	1	English
Canada	Source mapped Official source mapped; ingredient rule not imported	0	English and French
New Zealand	Evidence linked Prohibited Open this evidence	1	English
ASEAN	Evidence linked Prohibited Open this evidence	1	English and national languages
China	Evidence linked Prohibited Open this evidence	1	Chinese with selected English material
Japan	Source mapped Official source mapped; ingredient rule not imported	0	Japanese; official English translation available
South Korea	Source mapped Official source mapped; ingredient rule not imported	0	Korean with some English names
United States	Source mapped Official source mapped; ingredient rule not imported	0	English
Australia	Source mapped Official source mapped; ingredient rule not imported	0	English
Brazil	Source mapped Official source mapped; ingredient rule not imported	0	Portuguese with INCI crosswalks
India	Evidence linked Prohibited Open this evidence	1	English and Hindi
Saudi Arabia	Evidence linked Prohibited Open this evidence	1	Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 615-66-7

CAS 615-66-7PubChem CID 11998

2-Chloro-p-Phenylenediamine

2-chloro-1,4-phenylenediamine is a diamine that is 1,4-phenylenediamine substituted at position 2 by a chloro group. It has a role as a dye. It is a diamine and a member of monochlorobenzenes. It is functionally related to a 1,4-phenylenediamine. It is a conjugate base of a 2-chloro-1,4-phenylenediaminium. — ChEBI

IUPAC name: 2-chlorobenzene-1,4-diamine

Molecular formula: C6H7ClN2
Molecular weight: 142.58 g/mol
Exact mass: 142.0297759 Da
XLogP3: 1.6
Topological polar surface area: 52.0 Å²
Hydrogen-bond donors: 2
Hydrogen-bond acceptors: 2
Covalent units: 1
Defined stereocentres: 0

Also known as

2-Chloro-1,4-diaminobenzene1,4-Benzenediamine, 2-chloro-Ursol Brown O2-Chloro-1,4-phenylenediamine3-Chloro-4-aminoaniline1,4-Diamino-2-chlorobenzene2-Chloro-1,4-benzenediamineo-Chloro-p-phenylenediamine

16 more reported names

2-Chloro-4-phenylenediaminep-Phenylenediamine, 2-chloro-C.I. 760653-Chloro-p-fenylendiaminW949BCC82RCI 76065CHEBI:76598RefChem:470353210-441-22-Chlor-p-fenylendiamin3-Chlor-p-fenylendiaminHSDB 41262-Chlor-p-fenylendiamin [Czech]3-Chlor-p-fenylendiamin [Czech]2-Chloro-(1,4-phenylenediamine)3-Chloro-p-fenylendiamin [Czech]

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:76598
ChEMBL:CHEMBL1619318
EPA DTXSID:DTXSID3043944
PubMed:18058049
PubMed:11683837

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for 2-CHLORO-P-PHENYLENEDIAMINE

INCI name

2-CHLORO-P-PHENYLENEDIAMINE

Description

2-chloro-p-phenylenediamine

Record provenance

Inventory reference: 31495
Imported identity: 2-CHLORO-P-PHENYLENEDIAMINE
Source update: 16/11/2016

European Commission CosIng source notes

Annex records for 2-CHLORO-P-PHENYLENEDIAMINE

Annex II Shared CAS number

Entry 1384

2-chlorobenzene-1,4-diamine (2-Chloro-p-Phenylenediamine), its sulfate and dihydrochloride salts wh…

CAS: 615-66-7; 61702-44-1 (sulfate); 615-46-3 (dihydrochloride)

EC: 210-441-2; 262-915-3; 210-427-6

Key data

CAS

615-66-7

210-441-2

Restriction

—

Function

HAIR DYEING: Imparting color to hair. Hair dyeing preparations may be temporary, semi-permanent, or permanent, depending on the length of time the colorant remains on the hair.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#205 · 2-CHLORO-P-PHENYLENEDIAMINE

Ingredients with overlapping formulation functions

2-AMINOMETHYL-P-AMINOPHENOL HCLHAIR DYEING

2-CHLORO-5-NITRO-N-HYDROXYETHYL P-PHENYLENEDIAMINEHAIR DYEING

2-CHLORO-5-NITRO-N-HYDROXYETHYL-P-PHENYLENEDIAMINEHAIR DYEING

2-CHLORO-6-ETHYLAMINO-4-NITROPHENOLHAIR DYEING

2-CHLORO-P-PHENYLENEDIAMINE SULFATEHAIR DYEING

2-CYANOMETHOXY-P-PHENYLENEDIAMINEHAIR DYEING

2-CYANOMETHYL BENZIMIDAZOLEHAIR DYEING

2-ETHOXYMETHOXY-P-PHENYLENEDIAMINEHAIR DYEING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How 2-CHLORO-P-PHENYLENEDIAMINE appears in the CosIng inventory

The CosIng inventory lists 2-CHLORO-P-PHENYLENEDIAMINE as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.

2-CHLORO-P-PHENYLENEDIAMINE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

2-CHLORO-P-PHENYLENEDIAMINE appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

According to the EU CosIng inventory, 2-CHLORO-P-PHENYLENEDIAMINE carries the following function designation(s):

HAIR DYEING

CAS 615-66-7 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for 2-CHLORO-P-PHENYLENEDIAMINE

This page combines the CosIng inventory entry for 2-CHLORO-P-PHENYLENEDIAMINE with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research 2-CHLORO-P-PHENYLENEDIAMINE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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