SOLVENT RED 48
Solvent Red 48 is classed chemically as a fluoran color. It conforms to the formula. (To identify the colorant allowed for use in the European Union (EU), the INCI Name CI 45410 must be used, except for hair dye product…
SOLVENT RED 48 is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.
Regulatory evidence by market
No rule for this ingredient has been imported for any of the 13 markets tracked here.
That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.
Chemical identity and properties

D&C Red No. 27
Phloxine O is a xanthene dye that is fluorescein in which the hydrogens at positions 2',4',5' and 7' are replaced by bromo groups, and the hydrogens at positions 4,5,6 and 7 are replaced by chloro groups. It is a red synthetic pigment which is widely used in colored cosmetics (e.g. lipsticks and blushers). It has a role as a fluorescent dye. It is a polyphenol, a tetrachlorobenzene, a dibromobenzene, a gamma-lactone, a xanthene dye, an oxaspiro compound, an organic heteropentacyclic compound and a member of 2-benzofurans. It is functionally related to a fluorescein (lactone form). — ChEBI
- IUPAC name
- 2',4',5',7'-tetrabromo-4,5,6,7-tetrachloro-3',6'-dihydroxyspiro[2-benzofuran-3,9'-xanthene]-1-one
- Molecular formula
- C20H4Br4Cl4O5
- Molecular weight
- 785.7 g/mol
- Exact mass
- 785.54759 Da
- XLogP3
- 8.7
- Topological polar surface area
- 76.0 Ų
- Hydrogen-bond donors
- 2
- Hydrogen-bond acceptors
- 5
- Covalent units
- 1
- Defined stereocentres
- 0
Also known as
16 more reported names
External database identifiers
- ChEBI:CHEBI:156496
- ChEMBL:CHEMBL1580759
- EPA DTXSID:DTXSID2031089
- PubMed:22790816
- PubMed:22750685
- PubMed:22738951
- PubMed:22629466
- PubMed:22540024
- PubMed:22489144
- PubMed:22475185
- PubMed:22443542
- PubMed:22440610
- PubMed:22371815
- PubMed:22314381
- PubMed:22291963
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
Official European Commission record
- CosIng substance ID
- 105277
- Entry status
- Active
- Published in the Official Journal
- Yes
- Recorded by the Commission
- 2024-08-26
Fields as published by the European Commission. The link opens the entry itself, not a search for it.
Inventory details for SOLVENT RED 48
INCI name
SOLVENT RED 48
Description
Solvent Red 48 is classed chemically as a fluoran color. It conforms to the formula.
(To identify the colorant allowed for use in the European Union (EU), the INCI Name CI 45410 must be used, except for hair dye products).
Record provenance
- Inventory reference
- cosing-live-105277
- Imported identity
- SOLVENT RED 48
- Source update
- 2024-08-26
Annex records for SOLVENT RED 48
Key data
- COLORANT
- Exclusively or mainly intended to colour the cosmetic product, the body as a whole or certain parts thereof, by absorption or reflection of visible light. All authorised colorants are substances in the positive list of Annex IV to the Cosmetics Regulation 1223/2009.
Official EU ingredient-name evidence
The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.
Related inventory evidence
Ingredients with overlapping formulation functions
Additional official and scientific sources
11 external databases to check this identity in
Each link searches that source for this identity. What each source is, and its legal weight
How SOLVENT RED 48 appears in the CosIng inventory
The CosIng inventory lists SOLVENT RED 48 as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.
SOLVENT RED 48 is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.
Frequently asked questions
Source note for SOLVENT RED 48
This page reproduces the CosIng inventory entry for SOLVENT RED 48 from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.
Use this inventory page to research SOLVENT RED 48 and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.
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