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InventoryRef cosing-live-1052772024-08-26

SOLVENT RED 48

Solvent Red 48 is classed chemically as a fluoran color. It conforms to the formula. (To identify the colorant allowed for use in the European Union (EU), the INCI Name CI 45410 must be used, except for hair dye product…

SOLVENT RED 48 is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

Chemical identity and properties

PubChem 2D chemical structure for CAS 13473-26-2
CAS 13473-26-2PubChem CID 83511

D&C Red No. 27

Phloxine O is a xanthene dye that is fluorescein in which the hydrogens at positions 2',4',5' and 7' are replaced by bromo groups, and the hydrogens at positions 4,5,6 and 7 are replaced by chloro groups. It is a red synthetic pigment which is widely used in colored cosmetics (e.g. lipsticks and blushers). It has a role as a fluorescent dye. It is a polyphenol, a tetrachlorobenzene, a dibromobenzene, a gamma-lactone, a xanthene dye, an oxaspiro compound, an organic heteropentacyclic compound and a member of 2-benzofurans. It is functionally related to a fluorescein (lactone form). — ChEBI

IUPAC name
2',4',5',7'-tetrabromo-4,5,6,7-tetrachloro-3',6'-dihydroxyspiro[2-benzofuran-3,9'-xanthene]-1-one
Molecular formula
C20H4Br4Cl4O5
Molecular weight
785.7 g/mol
Exact mass
785.54759 Da
XLogP3
8.7
Topological polar surface area
76.0 Ų
Hydrogen-bond donors
2
Hydrogen-bond acceptors
5
Covalent units
1
Defined stereocentres
0

Also known as

D & C Red no. 27Phloxine OAcid Phloxine PBSolvent Red 482',4',5',7'-tetrabromo-4,5,6,7-tetrachlorofluoresceinPhloxine BBN SupraC.I. Solvent Red 48Japan Red 218
16 more reported names
D&C Red 27D&C red no.27TetrachlorotetrabromofluoresceinC,I, Solvent Red 48C.I. 45410AD and C Red No. 27Red No. 218CCRIS 4905CI 45410:1EINECS 236-747-62LRS185U6KTETRACHLOROEOSINCI Solvent Red 48DC RED NO. 27DYE DC RED NO. 27AKA218
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Official European Commission record

CosIng substance ID
105277
Entry status
Active
Published in the Official Journal
Yes
Recorded by the Commission
2024-08-26
Open this entry in the official CosIng database

Fields as published by the European Commission. The link opens the entry itself, not a search for it.

Inventory details for SOLVENT RED 48

INCI name

SOLVENT RED 48

Description

Solvent Red 48 is classed chemically as a fluoran color. It conforms to the formula.
(To identify the colorant allowed for use in the European Union (EU), the INCI Name CI 45410 must be used, except for hair dye products).

Record provenance

Inventory reference
cosing-live-105277
Imported identity
SOLVENT RED 48
Source update
2024-08-26
European Commission CosIng source notes

Key data

Restriction
—
Function
COLORANT
Exclusively or mainly intended to colour the cosmetic product, the body as a whole or certain parts thereof, by absorption or reflection of visible light. All authorised colorants are substances in the positive list of Annex IV to the Cosmetics Regulation 1223/2009.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

Ingredients with overlapping formulation functions

Additional official and scientific sources

11 external databases to check this identity in

How SOLVENT RED 48 appears in the CosIng inventory

The CosIng inventory lists SOLVENT RED 48 as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

SOLVENT RED 48 is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

SOLVENT RED 48 is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, SOLVENT RED 48 carries the following function designation(s):

CAS 13473-26-2 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

Source note for SOLVENT RED 48

This page reproduces the CosIng inventory entry for SOLVENT RED 48 from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research SOLVENT RED 48 and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

Tools & next steps

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