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InventoryRef cosing-live-1043062024-09-26

PIROCTONE

Piroctone is the organic compound that conforms to the formula

PIROCTONE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet. Inventory note: V/35.

Regulatory evidence by market

This matrix separates verified ingredient rules from sources that are mapped but not yet imported. No imported rule does not mean the ingredient is permitted.

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MarketEvidence statusRecordsSource language
European UnionSource mapped
Inventory entry; no linked annex rule
0English and EU languages
Great BritainSource mapped
Official source mapped; ingredient rule not imported
0English
CanadaSource mapped
Official source mapped; ingredient rule not imported
0English and French
New ZealandEvidence linked
Permitted list with conditions
Open this evidence
1English
ASEANSource mapped
Official source mapped; ingredient rule not imported
0English and national languages
ChinaSource mapped
Official source mapped; ingredient rule not imported
0Chinese with selected English material
JapanSource mapped
Official source mapped; ingredient rule not imported
0Japanese; official English translation available
South KoreaSource mapped
Official source mapped; ingredient rule not imported
0Korean with some English names
United StatesSource mapped
Official source mapped; ingredient rule not imported
0English
AustraliaSource mapped
Official source mapped; ingredient rule not imported
0English
BrazilSource mapped
Official source mapped; ingredient rule not imported
0Portuguese with INCI crosswalks
IndiaSource mapped
Official source mapped; ingredient rule not imported
0English and Hindi
Saudi ArabiaSource mapped
Official source mapped; ingredient rule not imported
0Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 50650-76-5
CAS 50650-76-5PubChem CID 50259

Piroctone

Piroctone is a cyclic hydroxamic acid that consists of 1-hydroxypyridin-2-one bearing methyl and 2,4,4-trimethylpentyl substtituents at positions 4 and 6 respectively. It has a role as an antiseborrheic. It is a cyclic hydroxamic acid, a pyridone and a hydroxypyridone antifungal drug. — ChEBI

IUPAC name
1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2-one
Molecular formula
C14H23NO2
Molecular weight
237.34 g/mol
Exact mass
237.172878976 Da
XLogP3
3.1
Topological polar surface area
40.5 Ų
Hydrogen-bond donors
1
Hydrogen-bond acceptors
2
Covalent units
1
Defined stereocentres
0

Also known as

PiroctonaPiroctonumPiroctonolPiroctonum [INN-Latin]1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2(1H)-pyridoneUNII-R49EFA73Q7R49EFA73Q7Piroctona [INN-Spanish]
16 more reported names
CHEBI:590091-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2(1H)-onePiroctonum (INN-Latin)Piroctona (INN-Spanish)1-hydroxy-4-methyl-6(2,4,4-trimethylpentyl)-2-pyridoneRefChem:578312(1H)-Pyridinone, 1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-Piroctone [USAN]Piroctone [USAN:INN]PIROCTONE [INN]PIROCTONE [MI]Piroctone (USAN/INN)PIROCTONE [WHO-DD]SCHEMBL3588AB01563386_01BRD-A96510685-213-01-1
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Official European Commission record

CosIng substance ID
104306
Published in the Official Journal
Yes
Recorded by the Commission
2024-09-26
Open this entry in the official CosIng database

Fields as published by the European Commission. The link opens the entry itself, not a search for it.

Inventory details for PIROCTONE

INCI name

PIROCTONE

Description

Piroctone is the organic compound that conforms to the formula

Record provenance

Inventory reference
cosing-live-104306
Imported identity
PIROCTONE
Source update
2024-09-26
European Commission CosIng source notes

Key data

EC
—
Restriction
V/35
Function
ANTIMICROBIAL
Preventing and/or slowing down microbial growth.
PRESERVATIVE
Exclusively or mainly intended to inhibit the development of micro-organisms in the cosmetic product. All authorised preservatives are substances in the positive list of Annex V to the Cosmetics Regulation 1223/2009.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

Ingredients with overlapping formulation functions

Additional official and scientific sources

11 external databases to check this identity in

How PIROCTONE appears in the CosIng inventory

The CosIng inventory lists PIROCTONE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

PIROCTONE is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

PIROCTONE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

The restriction field for PIROCTONE reads: "V/35". This is the restriction note recorded in the CosIng inventory for this ingredient. For authoritative conditions and limits, always refer to the linked annex entries above.

According to the EU CosIng inventory, PIROCTONE carries the following function designation(s):

CAS 50650-76-5 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

Source note for PIROCTONE

This page reproduces the CosIng inventory entry for PIROCTONE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research PIROCTONE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

Tools & next steps

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