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InventoryRef 9858912/10/2020

HYDROXYLATED DOCOSAHEXAENOIC ACID

Hydroxylated Docosahexaenoic Acid

HYDROXYLATED DOCOSAHEXAENOIC ACID is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

Chemical identity and properties

PubChem 2D chemical structure for CAS 578008-43-2
CAS 578008-43-2PubChem CID 25073195

Resolvin D5

IUPAC name
(4Z,7S,8E,10Z,13Z,15E,17S,19Z)-7,17-dihydroxydocosa-4,8,10,13,15,19-hexaenoic acid
Molecular formula
C22H32O4
Molecular weight
360.5 g/mol
Exact mass
360.23005950 Da
XLogP3
4.0
Topological polar surface area
77.8 Ų
Hydrogen-bond donors
3
Hydrogen-bond acceptors
4
Covalent units
1
Defined stereocentres
2

Also known as

RvD57S,17S-dihydroxy-4Z,8E,10Z,13Z,15E,19Z-docosahexaenoic acidRvD5 resolvinRefChem:178925CHEBI:1386457(S),17(S)-Resolvin D54,8,10,13,15,19-Docosahexaenoic acid, 7,17-dihydroxy-,(4Z,7S,8E,10Z,13Z,15E,17S,19Z)-(4Z,7S,8E,10Z,13Z,15E,17S,19Z)-7,17-Dihydroxy-4,8,10,13,15,19-docosahexaenoic Acid
2 more reported names
HY-145491CS-0375137
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 871826-47-0
CAS 871826-47-0PubChem CID 11667655

10S,17S-DiHDoHE

(4Z,7Z,10S,11E,13Z,15E,17S,19Z)-10,17-dihydroxydocosahexaenoic acid is a dihydroxydocosahexaenoic acid that is (4Z,7Z,11E,13Z,15E,19Z)-docosahexaenoic acid in which the two hydroxy substituents are located at positions 10 and 17 (the 10S,17S-stereoisomer). A natural isomer of protectin D1, one of the specialised proresolving mediators. It has a role as an anti-inflammatory agent and a human xenobiotic metabolite. It is a secondary allylic alcohol, a dihydroxydocosahexaenoic acid and a protectin. ChEBI

IUPAC name
(4Z,7Z,10S,11E,13Z,15E,17S,19Z)-10,17-dihydroxydocosa-4,7,11,13,15,19-hexaenoic acid
Molecular formula
C22H32O4
Molecular weight
360.5 g/mol
Exact mass
360.23005950 Da
XLogP3
4.0
Topological polar surface area
77.8 Ų
Hydrogen-bond donors
3
Hydrogen-bond acceptors
4
Covalent units
1
Defined stereocentres
2

Also known as

10S,17S-dihydroxy-4Z,7Z,11E,13Z,15E,19Z-docosahexaenoic acidRefChem:105732110(S),17(S)-DiHDoHE10(S),17(S)-DiHDHAProtectin DX10S,17S-diHDHACHEBI:138653CHEBI:140930
6 more reported names
HY-130285CS-0106472PDX; 10S,17S-DiHDoHE; 10S,17S-diHDHA10,17-dihydroxydocosa-4,7,11,13,15,19-hexaenoic acid(4Z,7Z,10S,11E,13Z,15E,17S,19Z)-10,17-dihydroxydocosahexaenoic acid10(S),17(S)-dihydroxydocosa-4Z,7Z,11E,13Z,15E,19Z-hexaenoic acid
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 90780-52-2
CAS 90780-52-2PubChem CID 6439179

(4Z,7Z,10Z,13Z,15E,19Z)-17-Hydroxy-4,7,10,13,15,19-docosahexaenoic acid

(4Z,7Z,10Z,13Z,15E,19Z)-17-hydroxydocosahexaenoic acid is a hydroxydocosahexaenoic acid that consists of 4Z,7Z,10Z,13Z,15E,19Z-docosahexaenoic acid bearing an additional 17-hydroxy substituent. It has a role as a human xenobiotic metabolite. It is a secondary allylic alcohol and a hydroxydocosahexaenoic acid. It is functionally related to an all-cis-docosa-4,7,10,13,16,19-hexaenoic acid. It is a conjugate acid of a (4Z,7Z,10Z,13Z,15E,19Z)-17-hydroxydocosahexaenoate. ChEBI

IUPAC name
(4Z,7Z,10Z,13Z,15E,19Z)-17-hydroxydocosa-4,7,10,13,15,19-hexaenoic acid
Molecular formula
C22H32O3
Molecular weight
344.5 g/mol
Exact mass
344.23514488 Da
XLogP3
5.1
Topological polar surface area
57.5 Ų
Hydrogen-bond donors
2
Hydrogen-bond acceptors
3
Covalent units
1
Defined stereocentres
0

Also known as

17-hydroxy-DHA17-Hdhe17-Hydroxydocosahexaenoic acid17-Hydroxy-4,7,10,13,15,19-docosahexaenoic acidRefChem:90617217-HDoHE17-HDHA(+/-)-17-HDoHE
16 more reported names
(+/-)-17-hydroxy-4Z,7Z,10Z,13Z,15E,19Z-docosahexaenoic acid(+/-)17-HDHA(4Z,7Z,10Z,13Z,15E,19Z)-17-Hydroxydocosahexaenoic acid4,7,10,13,15,19-Docosahexaenoicacid, 17-hydroxy-, (4Z,7Z,10Z,13Z,15E,19Z)-17(R)HDoHE(?)17-HDHASWTYBBUBEPPYCX-VIIQGJSXSA-N(4Z,7Z,10Z,13Z,15E,19Z)-17-hydroxydocosa-4,7,10,13,15,19-hexaenoate17-HydroxydocosahexaenoateCHEBI:72637(4Z,7Z,10Z,13E,15E,19Z)-17-Hydroxydocosa-4,7,10,13,15,19-hexaenoic acid(A+/-)17-HDHA(.+/-.)17-HDoHE(??)17-HDHA(+/-)-17-HDHAHY-113512
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for HYDROXYLATED DOCOSAHEXAENOIC ACID

INCI name

HYDROXYLATED DOCOSAHEXAENOIC ACID

Description

Hydroxylated Docosahexaenoic Acid

Record provenance

Inventory reference
98589
Imported identity
HYDROXYLATED DOCOSAHEXAENOIC ACID
Source update
12/10/2020
European Commission CosIng source notes

Key data

CAS
578008-43-2; 90780-52-2; 871826-47-0
EC
Restriction
Function
SKIN PROTECTING
Helping to avoid harmful effects to the skin from external factors.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

Ingredients with overlapping formulation functions

Additional official and scientific sources

11 external databases to check this identity in

How HYDROXYLATED DOCOSAHEXAENOIC ACID appears in the CosIng inventory

The CosIng inventory lists HYDROXYLATED DOCOSAHEXAENOIC ACID as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

HYDROXYLATED DOCOSAHEXAENOIC ACID is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

HYDROXYLATED DOCOSAHEXAENOIC ACID is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, HYDROXYLATED DOCOSAHEXAENOIC ACID carries the following function designation(s):

CAS 578008-43-2; 90780-52-2; 871826-47-0 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

Source note for HYDROXYLATED DOCOSAHEXAENOIC ACID

This page reproduces the CosIng inventory entry for HYDROXYLATED DOCOSAHEXAENOIC ACID from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research HYDROXYLATED DOCOSAHEXAENOIC ACID and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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