Official EU label nameGlossary entry 13291

HYDROXYLATED DOCOSAHEXAENOIC ACID

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 0 of 13 indexed market datasets: 0 country records and 0 EU Annex records. Every result and evidence gap is listed below.

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Resolved identifiers

Resolved substance identity

CAS:578008-43-290780-52-2871826-47-0

Ingredient index records:

HYDROXYLATED DOCOSAHEXAENOIC ACID

Cosmetic functions: SKIN PROTECTING

Hydroxylated Docosahexaenoic Acid

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1 matched or reported name

HYDROXYLATED DOCOSAHEXAENOIC ACID

Regulatory evidence across markets

None of the 13 markets tracked here holds an imported rule under the name HYDROXYLATED DOCOSAHEXAENOIC ACID.

That is a statement about this inventory, not about the law: no imported rule is not evidence that a substance is permitted. A rule may exist under a different name, under a CAS or EC number this glossary entry does not carry, or in a dataset not yet imported.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 578008-43-2

CAS 578008-43-2PubChem CID 25073195

Resolvin D5

IUPAC name: (4Z,7S,8E,10Z,13Z,15E,17S,19Z)-7,17-dihydroxydocosa-4,8,10,13,15,19-hexaenoic acid

Molecular formula: C22H32O4
Molecular weight: 360.5 g/mol
Exact mass: 360.23005950 Da
XLogP3: 4.0
Topological polar surface area: 77.8 Å²
Hydrogen-bond donors: 3
Hydrogen-bond acceptors: 4
Covalent units: 1
Defined stereocentres: 2

Also known as

RvD57S,17S-dihydroxy-4Z,8E,10Z,13Z,15E,19Z-docosahexaenoic acidRvD5 resolvinRefChem:178925CHEBI:1386457(S),17(S)-Resolvin D54,8,10,13,15,19-Docosahexaenoic acid, 7,17-dihydroxy-,(4Z,7S,8E,10Z,13Z,15E,17S,19Z)-(4Z,7S,8E,10Z,13Z,15E,17S,19Z)-7,17-Dihydroxy-4,8,10,13,15,19-docosahexaenoic Acid

2 more reported names

HY-145491CS-0375137

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External database identifiers

PubMed:16303609

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 871826-47-0

CAS 871826-47-0PubChem CID 11667655

10S,17S-DiHDoHE

(4Z,7Z,10S,11E,13Z,15E,17S,19Z)-10,17-dihydroxydocosahexaenoic acid is a dihydroxydocosahexaenoic acid that is (4Z,7Z,11E,13Z,15E,19Z)-docosahexaenoic acid in which the two hydroxy substituents are located at positions 10 and 17 (the 10S,17S-stereoisomer). A natural isomer of protectin D1, one of the specialised proresolving mediators. It has a role as an anti-inflammatory agent and a human xenobiotic metabolite. It is a secondary allylic alcohol, a dihydroxydocosahexaenoic acid and a protectin. — ChEBI

IUPAC name: (4Z,7Z,10S,11E,13Z,15E,17S,19Z)-10,17-dihydroxydocosa-4,7,11,13,15,19-hexaenoic acid

Molecular formula: C22H32O4
Molecular weight: 360.5 g/mol
Exact mass: 360.23005950 Da
XLogP3: 4.0
Topological polar surface area: 77.8 Å²
Hydrogen-bond donors: 3
Hydrogen-bond acceptors: 4
Covalent units: 1
Defined stereocentres: 2

Also known as

10S,17S-dihydroxy-4Z,7Z,11E,13Z,15E,19Z-docosahexaenoic acidRefChem:105732110(S),17(S)-DiHDoHE10(S),17(S)-DiHDHAProtectin DX10S,17S-diHDHACHEBI:138653CHEBI:140930

6 more reported names

HY-130285CS-0106472PDX; 10S,17S-DiHDoHE; 10S,17S-diHDHA10,17-dihydroxydocosa-4,7,11,13,15,19-hexaenoic acid(4Z,7Z,10S,11E,13Z,15E,17S,19Z)-10,17-dihydroxydocosahexaenoic acid10(S),17(S)-dihydroxydocosa-4Z,7Z,11E,13Z,15E,19Z-hexaenoic acid

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External database identifiers

ChEBI:CHEBI:138653
ChEBI:CHEBI:140930
EPA DTXSID:DTXSID50849502
PubMed:19818771

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 90780-52-2

CAS 90780-52-2PubChem CID 6439179

(4Z,7Z,10Z,13Z,15E,19Z)-17-Hydroxy-4,7,10,13,15,19-docosahexaenoic acid

(4Z,7Z,10Z,13Z,15E,19Z)-17-hydroxydocosahexaenoic acid is a hydroxydocosahexaenoic acid that consists of 4Z,7Z,10Z,13Z,15E,19Z-docosahexaenoic acid bearing an additional 17-hydroxy substituent. It has a role as a human xenobiotic metabolite. It is a secondary allylic alcohol and a hydroxydocosahexaenoic acid. It is functionally related to an all-cis-docosa-4,7,10,13,16,19-hexaenoic acid. It is a conjugate acid of a (4Z,7Z,10Z,13Z,15E,19Z)-17-hydroxydocosahexaenoate. — ChEBI

IUPAC name: (4Z,7Z,10Z,13Z,15E,19Z)-17-hydroxydocosa-4,7,10,13,15,19-hexaenoic acid

Molecular formula: C22H32O3
Molecular weight: 344.5 g/mol
Exact mass: 344.23514488 Da
XLogP3: 5.1
Topological polar surface area: 57.5 Å²
Hydrogen-bond donors: 2
Hydrogen-bond acceptors: 3
Covalent units: 1
Defined stereocentres: 0

Also known as

17-hydroxy-DHA17-Hdhe17-Hydroxydocosahexaenoic acid17-Hydroxy-4,7,10,13,15,19-docosahexaenoic acidRefChem:90617217-HDoHE17-HDHA(+/-)-17-HDoHE

16 more reported names

(+/-)-17-hydroxy-4Z,7Z,10Z,13Z,15E,19Z-docosahexaenoic acid(+/-)17-HDHA(4Z,7Z,10Z,13Z,15E,19Z)-17-Hydroxydocosahexaenoic acid4,7,10,13,15,19-Docosahexaenoicacid, 17-hydroxy-, (4Z,7Z,10Z,13Z,15E,19Z)-17(R)HDoHE(?)17-HDHASWTYBBUBEPPYCX-VIIQGJSXSA-N(4Z,7Z,10Z,13Z,15E,19Z)-17-hydroxydocosa-4,7,10,13,15,19-hexaenoate17-HydroxydocosahexaenoateCHEBI:72637(4Z,7Z,10Z,13E,15E,19Z)-17-Hydroxydocosa-4,7,10,13,15,19-hexaenoic acid(A+/-)17-HDHA(.+/-.)17-HDoHE(??)17-HDHA(+/-)-17-HDHAHY-113512

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External database identifiers

ChEBI:CHEBI:72637
EPA DTXSID:DTXSID80904335
PubMed:34601004
PubMed:29968805
PubMed:21724996
PubMed:20671299
PubMed:17056761

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Additional authoritative substance research

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Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal US EPA CompTox CTX APIs

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Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

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