OLEUROPEIN
methyl (2S,3E,4S)-4-{2-[2-(3,4-dihydroxyphenyl)ethoxy]-2-oxoethyl}-3-ethylidene-2-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-3,4-dihydro-2H-pyran-5-carboxylate
OLEUROPEIN is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.
Regulatory evidence by market
No rule for this ingredient has been imported for any of the 13 markets tracked here.
That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.
Chemical identity and properties
Oleuropein
Oleuropein is a secoiridoid glycoside that is the methyl ester of 3,4-dihydro-2H-pyran-5-carboxylic acid which is substituted at positions 2, 3, and 4 by hydroxy, ethylidene, and carboxymethyl groups, respectively and in which the anomeric hydroxy group at position 2 has been converted into its beta-D-glucoside and the carboxylic acid moiety of the carboxymethyl substituent has been converted to the corresponding 3,4-dihydroxyphenethyl ester (the 2S,3E,4S stereoisomer). The most important phenolic compound present in olive cultivars. It has a role as an antioxidant, an antineoplastic agent, an antihypertensive agent, a radical scavenger, a nutraceutical, an anti-inflammatory agent, an apoptosis inducer, a NF-kappaB inhibitor and a plant metabolite. It is a beta-D-glucoside, a methyl ester, a member of pyrans, a member of catechols, a secoiridoid glycoside and a diester. — ChEBI
- IUPAC name
- methyl (4S,5E,6S)-4-[2-[2-(3,4-dihydroxyphenyl)ethoxy]-2-oxoethyl]-5-ethylidene-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4H-pyran-3-carboxylate
- Molecular formula
- C25H32O13
- Molecular weight
- 540.5 g/mol
- Exact mass
- 540.18429107 Da
- XLogP3
- -0.4
- Topological polar surface area
- 202.0 Ų
- Hydrogen-bond donors
- 6
- Hydrogen-bond acceptors
- 13
- Covalent units
- 1
- Defined stereocentres
- 7
Also known as
16 more reported names
External database identifiers
- ChEBI:CHEBI:7747
- ChEMBL:CHEMBL1911053
- EPA DTXSID:DTXSID60905103
- PubMed:36774383
- PubMed:34785711
- PubMed:34126350
- PubMed:29414845
- PubMed:28595958
- PubMed:27847271
- PubMed:27019295
- PubMed:26056852
- PubMed:22595400
- PubMed:21179340
- PubMed:18823963
- PubMed:17910019
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
Inventory details for OLEUROPEIN
INCI name
OLEUROPEIN
Description
methyl (2S,3E,4S)-4-{2-[2-(3,4-dihydroxyphenyl)ethoxy]-2-oxoethyl}-3-ethylidene-2-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-3,4-dihydro-2H-pyran-5-carboxylate
Record provenance
- Inventory reference
- 96932
- Imported identity
- OLEUROPEIN
- Source update
- 16/04/2019
Annex records for OLEUROPEIN
Key data
- ANTIOXIDANT
- Inhibiting reactions promoted by oxygen, thus avoiding oxidation and rancidity.
- HAIR CONDITIONING
- Enhancing the appearance and feel of hair. Leaving the hair easy to comb, supple, soft and shiny and/or imparting volume, lightness, gloss, texture, etc.
- HAIR FIXING
- Permitting physical control of hair style.
- HAIR WAVING OR STRAIGHTENING
- Modifying the chemical structure of the hair, allowing it to be set in the style required (permanent waves or hair straightening).
Official EU ingredient-name evidence
The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.
Related inventory evidence
Ingredients with overlapping formulation functions
Additional official and scientific sources
11 external databases to check this identity in
Each link searches that source for this identity. What each source is, and its legal weight
How OLEUROPEIN appears in the CosIng inventory
The CosIng inventory lists OLEUROPEIN as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.
OLEUROPEIN is also tagged with 4 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.
Frequently asked questions
Source note for OLEUROPEIN
This page reproduces the CosIng inventory entry for OLEUROPEIN from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.
Use this inventory page to research OLEUROPEIN and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.
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