Official EU label nameGlossary entry 18032

OLEUROPEIN

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 0 of 13 indexed market datasets: 0 country records and 0 EU Annex records. Every result and evidence gap is listed below.

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Resolved identifiers

Resolved substance identity

CAS:32619-42-4

EC:215-129-6

Ingredient index records:

OLEUROPEIN

Cosmetic functions: ANTIOXIDANT, HAIR CONDITIONING, HAIR FIXING, HAIR WAVING OR STRAIGHTENING

methyl (2S,3E,4S)-4-{2-[2-(3,4-dihydroxyphenyl)ethoxy]-2-oxoethyl}-3-ethylidene-2-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-3,4-dihydro-2H-pyran-5-carboxylate

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1 matched or reported name

OLEUROPEIN

Regulatory evidence across markets

None of the 13 markets tracked here holds an imported rule under the name OLEUROPEIN.

That is a statement about this inventory, not about the law: no imported rule is not evidence that a substance is permitted. A rule may exist under a different name, under a CAS or EC number this glossary entry does not carry, or in a dataset not yet imported.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 32619-42-4

CAS 32619-42-4PubChem CID 5281544

Oleuropein

Oleuropein is a secoiridoid glycoside that is the methyl ester of 3,4-dihydro-2H-pyran-5-carboxylic acid which is substituted at positions 2, 3, and 4 by hydroxy, ethylidene, and carboxymethyl groups, respectively and in which the anomeric hydroxy group at position 2 has been converted into its beta-D-glucoside and the carboxylic acid moiety of the carboxymethyl substituent has been converted to the corresponding 3,4-dihydroxyphenethyl ester (the 2S,3E,4S stereoisomer). The most important phenolic compound present in olive cultivars. It has a role as an antioxidant, an antineoplastic agent, an antihypertensive agent, a radical scavenger, a nutraceutical, an anti-inflammatory agent, an apoptosis inducer, a NF-kappaB inhibitor and a plant metabolite. It is a beta-D-glucoside, a methyl ester, a member of pyrans, a member of catechols, a secoiridoid glycoside and a diester. — ChEBI

IUPAC name: methyl (4S,5E,6S)-4-[2-[2-(3,4-dihydroxyphenyl)ethoxy]-2-oxoethyl]-5-ethylidene-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4H-pyran-3-carboxylate

Molecular formula: C25H32O13
Molecular weight: 540.5 g/mol
Exact mass: 540.18429107 Da
XLogP3: -0.4
Topological polar surface area: 202.0 Å²
Hydrogen-bond donors: 6
Hydrogen-bond acceptors: 13
Covalent units: 1
Defined stereocentres: 7

Also known as

OleoeuropeinoleoeuropeineCHEBI:77472-(3,4-Dihydroxyphenyl)ethyl (2S-(2alpha,3E,4beta))-3-ethylidene-2-(beta-D-glucopyranosyloxy)-3,4-dihydro-5-(methoxycarbonyl)-2H-pyran-4-acetate2O4553545LRefChem:168112251-129-6Oleuropein, 75%

16 more reported names

Oleuropein, >95%CCG-2699612H-Pyran-4-acetic acid, 3-ethylidene-2-(.beta.-D-glucopyranosyloxy)-3,4-dihydro-5-(methoxycarbonyl)-, 2-(3,4-dihydroxyphenyl)ethyl ester, (2S,3E,4S)-methyl (2S,3E,4S)-4-{2-[2-(3,4-dihydroxyphenyl)ethoxy]-2-oxoethyl}-3-ethylidene-2-(beta-D-glucopyranosyloxy)-3,4-dihydro-2H-pyran-5-carboxylateEINECS 251-129-6OleuropeineOleuroperinOleuropein CRSUNII-2O4553545LOleuropein (Standard)Oleuropein (>75%)OLEUROPEIN [MI]OLEUROPEIN [VANDF]Oleuropein, >=98.0%OLEUROPEIN [USP-RS]OLEUROPEIN [WHO-DD]

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External database identifiers

ChEBI:CHEBI:7747
ChEMBL:CHEMBL1911053
EPA DTXSID:DTXSID60905103
PubMed:36774383
PubMed:34785711
PubMed:34126350
PubMed:29414845
PubMed:28595958
PubMed:27847271
PubMed:27019295
PubMed:26056852
PubMed:22595400
PubMed:21179340
PubMed:18823963
PubMed:17910019

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Additional authoritative substance research

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Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal US EPA CompTox CTX APIs

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Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

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