
Oleuropein
Oleuropein is a secoiridoid glycoside that is the methyl ester of 3,4-dihydro-2H-pyran-5-carboxylic acid which is substituted at positions 2, 3, and 4 by hydroxy, ethylidene, and carboxymethyl groups, respectively and in which the anomeric hydroxy group at position 2 has been converted into its beta-D-glucoside and the carboxylic acid moiety of the carboxymethyl substituent has been converted to the corresponding 3,4-dihydroxyphenethyl ester (the 2S,3E,4S stereoisomer). The most important phenolic compound present in olive cultivars. It has a role as an antioxidant, an antineoplastic agent, an antihypertensive agent, a radical scavenger, a nutraceutical, an anti-inflammatory agent, an apoptosis inducer, a NF-kappaB inhibitor and a plant metabolite. It is a beta-D-glucoside, a methyl ester, a member of pyrans, a member of catechols, a secoiridoid glycoside and a diester. — ChEBI
- IUPAC name
- methyl (4S,5E,6S)-4-[2-[2-(3,4-dihydroxyphenyl)ethoxy]-2-oxoethyl]-5-ethylidene-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4H-pyran-3-carboxylate
- Molecular formula
- C25H32O13
- Molecular weight
- 540.5 g/mol
- Exact mass
- 540.18429107 Da
- XLogP3
- -0.4
- Topological polar surface area
- 202.0 Ų
- Hydrogen-bond donors
- 6
- Hydrogen-bond acceptors
- 13
- Covalent units
- 1
- Defined stereocentres
- 7
Also known as
16 more reported names
External database identifiers
- ChEBI:CHEBI:7747
- ChEMBL:CHEMBL1911053
- EPA DTXSID:DTXSID60905103
- PubMed:36774383
- PubMed:34785711
- PubMed:34126350
- PubMed:29414845
- PubMed:28595958
- PubMed:27847271
- PubMed:27019295
- PubMed:26056852
- PubMed:22595400
- PubMed:21179340
- PubMed:18823963
- PubMed:17910019
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.