Is THIOXANTHONE safe to use in EU cosmetics?

THIOXANTHONE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Always verify against the current official CosIng database before formulating.

What other records share CAS 492-22-8?

CAS 492-22-8 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains THIOXANTHONE?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 9734728/10/2019

THIOXANTHONE

9H-Thioxanthen-9-one

THIOXANTHONE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 492-22-8

CAS 492-22-8PubChem CID 10295

Thioxanthone

IUPAC name: thioxanthen-9-one

Molecular formula: C13H8OS
Molecular weight: 212.27 g/mol
Exact mass: 212.02958605 Da
XLogP3: 4.0
Topological polar surface area: 42.4 Å²
Hydrogen-bond donors: 0
Hydrogen-bond acceptors: 2
Covalent units: 1
Defined stereocentres: 0

Also known as

9H-THIOXANTHEN-9-ONE9-ThioxanthoneThiaxanthenoneThioxanthenoneThiaxanthon9H-Thioxanthene, 9-oxo-EOK1SAC304NSC-15912

16 more reported names

NSC-658181RefChem:189678207-749-4ThiaxanthoneThioxanthene-9-one9-Oxothioxanthene10-ThioxanthoneThioxanthene, 9-oxo-9-Oxothioxanthene,ThioxanthoneNSC 15912NSC 658181Metixene Hydrochloride EP Impurity BAC-15767CS-0097787dibenzo[b,e]thiin-10-one9H-Thioxanthen-9-one (Thioxanthone)

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEMBL:CHEMBL83371
EPA DTXSID:DTXSID8060082
PubMed:23208609
PubMed:23083514
PubMed:22803611
PubMed:22763984
PubMed:22218680
PubMed:22111869
PubMed:22090935
PubMed:22044878
PubMed:21820349
PubMed:21711009
PubMed:21612295
PubMed:21582265

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for THIOXANTHONE

INCI name

THIOXANTHONE

Description

9H-Thioxanthen-9-one

Record provenance

Inventory reference: 97347
Imported identity: THIOXANTHONE
Source update: 28/10/2019

European Commission CosIng source notes

Annex records for THIOXANTHONE

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Key data

CAS

492-22-8

207-749-4

Restriction

—

Function

NOT REPORTED: No function currently reported.

Ingredients with overlapping formulation functions

TETRAPEPTIDE-72NOT REPORTED

TETRAPEPTIDE-74NOT REPORTED

TETRAPEPTIDE-75NOT REPORTED

TETRAPEPTIDE-98NOT REPORTED

TITANIUM TETRA T-BUTOXIDENOT REPORTED

TITANUM TETRA T-BUTOXIDENOT REPORTED

TOLUENE DIISOCYANATENOT REPORTED

TRIFLUOROMETHYL DEHYDROLATANOPROSTNOT REPORTED

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How THIOXANTHONE appears in the CosIng inventory

The CosIng inventory lists THIOXANTHONE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

THIOXANTHONE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

THIOXANTHONE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, THIOXANTHONE carries the following function designation(s):

NOT REPORTED

CAS 492-22-8 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for THIOXANTHONE

This page reproduces the CosIng inventory entry for THIOXANTHONE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research THIOXANTHONE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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Tools & next steps

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