What does the restriction note for N-FERULOYL DOPAMINE mean?

The restriction field for N-FERULOYL DOPAMINE reads: II/21. This is the restriction note from the CosIng inventory. For authoritative conditions and limits, always refer to the linked annex entries.

What other records share CAS 142350-99-0?

CAS 142350-99-0 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains N-FERULOYL DOPAMINE?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 9118313/05/2019

N-FERULOYL DOPAMINE

2-Propenamide, N-[2-(3,4-dihydroxyphenyl)ethyl]-3-(4-hydroxy-3-methoxyphenyl)-, (2E)-

N-FERULOYL DOPAMINE is linked to 1 EU annex record on this page. Inventory note: II/21.

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Regulatory evidence by market

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Market	Evidence status	Records	Source language
European Union	Evidence linked Prohibited entry found Open this evidence	1	English and EU languages
Great Britain	Source mapped Official source mapped; ingredient rule not imported	0	English
Canada	Source mapped Official source mapped; ingredient rule not imported	0	English and French
New Zealand	Source mapped Official source mapped; ingredient rule not imported	0	English
ASEAN	Source mapped Official source mapped; ingredient rule not imported	0	English and national languages
China	Source mapped Official source mapped; ingredient rule not imported	0	Chinese with selected English material
Japan	Source mapped Official source mapped; ingredient rule not imported	0	Japanese; official English translation available
South Korea	Source mapped Official source mapped; ingredient rule not imported	0	Korean with some English names
United States	Source mapped Official source mapped; ingredient rule not imported	0	English
Australia	Source mapped Official source mapped; ingredient rule not imported	0	English
Brazil	Source mapped Official source mapped; ingredient rule not imported	0	Portuguese with INCI crosswalks
India	Source mapped Official source mapped; ingredient rule not imported	0	English and Hindi
Saudi Arabia	Source mapped Official source mapped; ingredient rule not imported	0	Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 142350-99-0

CAS 142350-99-0PubChem CID 16119330

Feruloyldopamine

trans-N-feruloyl dopamine has been reported in Mitrephora thorelii, Peperomia heyneana, and Mitrephora tomentosa with data available. — LOTUS - the natural products occurrence database

IUPAC name: (E)-N-[2-(3,4-dihydroxyphenyl)ethyl]-3-(4-hydroxy-3-methoxyphenyl)prop-2-enamide

Molecular formula: C18H19NO5
Molecular weight: 329.3 g/mol
Exact mass: 329.12632271 Da
XLogP3: 1.7
Topological polar surface area: 99.0 Å²
Hydrogen-bond donors: 4
Hydrogen-bond acceptors: 5
Covalent units: 1
Defined stereocentres: 0

Also known as

RefChem:43040N-Feruloyl dopamine, trans-N-Trans-Feruloyldopaminetrans-FeruloyldopamineUNII-NGL0OTK5E8NGL0OTK5E82-Propenamide, N-(2-(3,4-dihydroxyphenyl)ethyl)-3-(4-hydroxy-3-methoxyphenyl)-, (2E)-2-Propenamide, N-(2-(3,4-dihydroxyphenyl)ethyl)-3-(4-hydroxy-3-methoxyphenyl)-, (E)-

8 more reported names

Feruloyl dopaminetrans-N-feruloyldopamineN-FERYLOYLDOPAMINEN-trans-feruloyl dopaminetrans-N-feruloyl dopamineZRLYUFOWFPPSTD-QPJJXVBHSA-Ntrans-N-feruloyl-3-hydroxytyramine(2E)-N-[2-(3,4-dihydroxyphenyl)ethyl]-3-(4-hydroxy-3-methoxyphenyl)prop-2-enamide

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEMBL:CHEMBL202844
EPA DTXSID:DTXSID70162023

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for N-FERULOYL DOPAMINE

INCI name

N-FERULOYL DOPAMINE

Description

2-Propenamide, N-[2-(3,4-dihydroxyphenyl)ethyl]-3-(4-hydroxy-3-methoxyphenyl)-, (2E)-

Record provenance

Inventory reference: 91183
Imported identity: N-FERULOYL DOPAMINE
Source update: 13/05/2019

European Commission CosIng source notes

Annex records for N-FERULOYL DOPAMINE

Annex II Restriction reference

Entry 21

Sympathicomimetic amines acting on the central nervous system: any substance contained in the first…

CAS: 300-62-9

EC: 206-096-2

Key data

CAS

142350-99-0

—

Restriction

II/21

Function

SKIN CONDITIONING: Maintaining the skin in good condition.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#17373 · N-FERULOYL DOPAMINE

Ingredients with overlapping formulation functions

N-ACETYL DIHYDROSPHINGOSINEHAIR CONDITIONING, SKIN CONDITIONING

N-ACETYLSALICYLOYL PHYTOSPHINGOSINESKIN CONDITIONING, SKIN PROTECTING

N-BENZYL-4-METHYL-O-PHENYLENEDIAMINESKIN CONDITIONING

N-CAPRYLOYL LYSINEHAIR CONDITIONING, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SKIN PROTECTING

N-HYALURONOYL 5-HYDROXYDOPAMINEHUMECTANT, SKIN CONDITIONING, SKIN PROTECTING

N-HYDROXYSUCCINIMIDESKIN CONDITIONING

N-LINOLENOYL SERINOLSKIN CONDITIONING

N-LINOLEOYL SERINOLSKIN CONDITIONING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How N-FERULOYL DOPAMINE appears in the CosIng inventory

The CosIng inventory lists N-FERULOYL DOPAMINE as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.

N-FERULOYL DOPAMINE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

N-FERULOYL DOPAMINE appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

The restriction field for N-FERULOYL DOPAMINE reads: "II/21". This is the restriction note recorded in the CosIng inventory for this ingredient. For authoritative conditions and limits, always refer to the linked annex entries above.

According to the EU CosIng inventory, N-FERULOYL DOPAMINE carries the following function designation(s):

SKIN CONDITIONING

CAS 142350-99-0 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for N-FERULOYL DOPAMINE

This page combines the CosIng inventory entry for N-FERULOYL DOPAMINE with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research N-FERULOYL DOPAMINE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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