What does the restriction note for N-HYALURONOYL 5-HYDROXYDOPAMINE mean?

The restriction field for N-HYALURONOYL 5-HYDROXYDOPAMINE reads: II/21. This is the restriction note from the CosIng inventory. For authoritative conditions and limits, always refer to the linked annex entries.

How do I check if my formula contains N-HYALURONOYL 5-HYDROXYDOPAMINE?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 9638513/05/2019

N-HYALURONOYL 5-HYDROXYDOPAMINE

5-Hydroxydopamine Hyaluronamide, Pyrogallolethyl Hyaluronamide

N-HYALURONOYL 5-HYDROXYDOPAMINE is linked to 1 EU annex record on this page. Inventory note: II/21.

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Regulatory evidence by market

This matrix separates verified ingredient rules from sources that are mapped but not yet imported. No imported rule does not mean the ingredient is permitted.

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Market	Evidence status	Records	Source language
European Union	Evidence linked Prohibited entry found Open this evidence	1	English and EU languages
Great Britain	Source mapped Official source mapped; ingredient rule not imported	0	English
Canada	Source mapped Official source mapped; ingredient rule not imported	0	English and French
New Zealand	Source mapped Official source mapped; ingredient rule not imported	0	English
ASEAN	Source mapped Official source mapped; ingredient rule not imported	0	English and national languages
China	Source mapped Official source mapped; ingredient rule not imported	0	Chinese with selected English material
Japan	Source mapped Official source mapped; ingredient rule not imported	0	Japanese; official English translation available
South Korea	Source mapped Official source mapped; ingredient rule not imported	0	Korean with some English names
United States	Source mapped Official source mapped; ingredient rule not imported	0	English
Australia	Source mapped Official source mapped; ingredient rule not imported	0	English
Brazil	Source mapped Official source mapped; ingredient rule not imported	0	Portuguese with INCI crosswalks
India	Source mapped Official source mapped; ingredient rule not imported	0	English and Hindi
Saudi Arabia	Source mapped Official source mapped; ingredient rule not imported	0	Arabic and English

Exact external identity check

not_found

No complete-name PubChem match was verified. The material may be a mixture, trade-style INCI identity or be indexed under another identifier; this result must not be read as proof that no related chemistry exists.

Exact CosIng INCI name equals a PubChem synonym · Checked 2026-08-31

Inventory details for N-HYALURONOYL 5-HYDROXYDOPAMINE

INCI name

N-HYALURONOYL 5-HYDROXYDOPAMINE

Description

5-Hydroxydopamine Hyaluronamide, Pyrogallolethyl Hyaluronamide

Record provenance

Inventory reference: 96385
Imported identity: N-HYALURONOYL 5-HYDROXYDOPAMINE
Source update: 13/05/2019

European Commission CosIng source notes

Annex records for N-HYALURONOYL 5-HYDROXYDOPAMINE

Annex II Restriction reference

Entry 21

Sympathicomimetic amines acting on the central nervous system: any substance contained in the first…

CAS: 300-62-9

EC: 206-096-2

Key data

CAS

—

The CosIng inventory records no CAS number for this ingredient. That is the absence of an identifier in the source, not a finding about the substance.

—

Restriction

II/21

Function

HUMECTANT: Retaining and/or preserving the moisture in a product during use.
SKIN CONDITIONING: Maintaining the skin in good condition.
SKIN PROTECTING: Helping to avoid harmful effects to the skin from external factors.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#17375 · N-HYALURONOYL 5-HYDROXYDOPAMINE

Ingredients with overlapping formulation functions

MYRISTYL 3-GLYCERYL ASCORBATEANTIOXIDANT, HUMECTANT

MYROTHAMNUS FLABELLIFOLIA CALLUS CULTURE EXTRACTANTIOXIDANT, HAIR CONDITIONING, HUMECTANT, SKIN CONDITIONING, SKIN PROTECTING

MYROTHAMNUS FLABELLIFOLIA EXTRACTHUMECTANT

MYROTHAMNUS FLABELLIFOLIA LEAF/STEM EXTRACTHUMECTANT, SKIN CONDITIONING

N-HYALURONOYL LACTOFERRINHUMECTANT

N-PALMITOYL LAURYLACETYLMETHYL AMINOPROPANEDIOLHUMECTANT, SKIN CONDITIONING

NANDINA DOMESTICA LEAF EXTRACTHUMECTANT

NANNOCHLOROPSIS OCEANICA POWDERANTIOXIDANT, HUMECTANT, SKIN CONDITIONING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How N-HYALURONOYL 5-HYDROXYDOPAMINE appears in the CosIng inventory

The CosIng inventory lists N-HYALURONOYL 5-HYDROXYDOPAMINE as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.

N-HYALURONOYL 5-HYDROXYDOPAMINE is also tagged with 3 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

N-HYALURONOYL 5-HYDROXYDOPAMINE appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

The restriction field for N-HYALURONOYL 5-HYDROXYDOPAMINE reads: "II/21". This is the restriction note recorded in the CosIng inventory for this ingredient. For authoritative conditions and limits, always refer to the linked annex entries above.

According to the EU CosIng inventory, N-HYALURONOYL 5-HYDROXYDOPAMINE carries the following function designation(s):

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Source note for N-HYALURONOYL 5-HYDROXYDOPAMINE

This page combines the CosIng inventory entry for N-HYALURONOYL 5-HYDROXYDOPAMINE with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research N-HYALURONOYL 5-HYDROXYDOPAMINE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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