DYPHYLLINE
1,3-Dimethyl-7-(2,3-Dihydroxypropyl) Xanthine; Diprophylline; Theophylline, 7-(2,3-dihydroxypropyl)-
DYPHYLLINE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.
Regulatory evidence by market
No rule for this ingredient has been imported for any of the 13 markets tracked here.
That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.
Chemical identity and properties
Diprophylline
Dyphylline is an oxopurine that is theophylline bearing a 2,3-dihydroxypropyl group at the 7 position. It has broncho- and vasodilator properties, and is used in the treatment of asthma, cardiac dyspnea, and bronchitis. It is also an ingredient in preparations that have been promoted for coughs. It has a role as a bronchodilator agent, a vasodilator agent, an EC 3.1.4.* (phosphoric diester hydrolase) inhibitor and a muscle relaxant. It is an oxopurine and a member of propane-1,2-diols. — ChEBI
- IUPAC name
- 7-(2,3-dihydroxypropyl)-1,3-dimethylpurine-2,6-dione
- Molecular formula
- C10H14N4O4
- Molecular weight
- 254.24 g/mol
- Exact mass
- 254.10150494 Da
- XLogP3
- -1.8
- Topological polar surface area
- 98.9 Ų
- Hydrogen-bond donors
- 2
- Hydrogen-bond acceptors
- 5
- Covalent units
- 1
- Defined stereocentres
- 0
Also known as
16 more reported names
External database identifiers
- ChEBI:CHEBI:4728
- ChEMBL:CHEMBL1752
- EPA DTXSID:DTXSID6022975
- PubMed:22662200
- PubMed:22321288
- PubMed:22245221
- PubMed:22113078
- PubMed:22008146
- PubMed:21515350
- PubMed:21042488
- PubMed:20638213
- PubMed:20026047
- PubMed:19778159
- PubMed:19755002
- PubMed:19737588
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
Inventory details for DYPHYLLINE
INCI name
DYPHYLLINE
INN name
Dyphylline [USAN]
Description
1,3-Dimethyl-7-(2,3-Dihydroxypropyl) Xanthine; Diprophylline; Theophylline, 7-(2,3-dihydroxypropyl)-
Record provenance
- Inventory reference
- 83278
- Imported identity
- DYPHYLLINE
- Source update
- 15/10/2010
Annex records for DYPHYLLINE
Key data
Official EU ingredient-name evidence
The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.
Related inventory evidence
Ingredients with overlapping formulation functions
Additional official and scientific sources
11 external databases to check this identity in
Each link searches that source for this identity. What each source is, and its legal weight
How DYPHYLLINE appears in the CosIng inventory
The CosIng inventory lists DYPHYLLINE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.
DYPHYLLINE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.
Frequently asked questions
Source note for DYPHYLLINE
This page reproduces the CosIng inventory entry for DYPHYLLINE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.
Use this inventory page to research DYPHYLLINE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.
Tools & next steps
Check your formula
Scan a full INCI list to detect DYPHYLLINE and any linked EU annex restrictions or allergen flags.
INCI CheckerSearch similar ingredients
Find other inventory ingredients and annex entries related to DYPHYLLINE, its identifiers or nearby name variants.
Search