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InventoryRef 7842415/10/2010

PALMITOYL CARNITINE

1-Propanaminium, 3-carboxy-2-(1-oxohexadecyloxy)-N,N,N-trimethyl-, hydroxide, inner salt

PALMITOYL CARNITINE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 1935-18-8

CAS 1935-18-8PubChem CID 461

(+-)-Palmitoyl carnitine

O-palmitoylcarnitine is an O-acylcarnitine having palmitoyl (hexadecanoyl) as the acyl substituent. It has a role as a metabolite. It is functionally related to a hexadecanoic acid. — ChEBI

IUPAC name: 3-hexadecanoyloxy-4-(trimethylazaniumyl)butanoate

Molecular formula: C23H45NO4
Molecular weight: 399.6 g/mol
Exact mass: 399.33485892 Da
XLogP3: 7.7
Topological polar surface area: 66.4 Å²
Hydrogen-bond donors: 0
Hydrogen-bond acceptors: 4
Covalent units: 1
Defined stereocentres: 0

Also known as

PALMITOYLCARNITINEPalmitylcarnitineU8K6DKA8V21-Propanaminium, 3-carboxy-N,N,N-trimethyl-2-((1-oxohexadecyl)oxy)-, inner saltRefChem:905514O-palmitoylcarnitine(+/-)-palmitoyl carnitineO-hexadecanoylcarnitine

16 more reported names

3-(hexadecanoyloxy)-4-(trimethylazaniumyl)butanoatePALMITOYL-CARNITINE1-Propanaminium,3-carboxy-N,N,N-trimethyl-2-[(1-oxohexadecyl)oxy]-, inner saltCHEBI:73067palmitoyl-dl-carnitine3-(hexadecanoyloxy)-4-(trimethylammonio)butanoateC23H45NO4(+-)-3-Carboxy-N,N,N-trimethyl-2-((1-oxohexadecyl)oxy)-1-propanaminium inner saltPALMITIC ACID, ESTER WITH (3-CARBOXY-2-HYDROXYPROPYL)TRIMETHYLAMMONIUM HYDROXIDE INNER SALTUNII-U8K6DKA8V2carnitine palmitatehexadecanoylcarnitinesAcylcarnitine C16:01-ProDL-PALMITOYLCARNITINEPALMITYL-DL-CARNITINE

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:73067
ChEMBL:CHEMBL301722
EPA DTXSID:DTXSID90895028
PubMed:38906090
PubMed:31040181
PubMed:24709313
PubMed:19700627

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 2364-67-2

CAS 2364-67-2PubChem CID 11953816

Palmitoyl Carnitine

O-palmitoyl-L-carnitine is an O-acyl-L-carnitine in which the acyl group is specified as palmitoyl (hexadecanoyl). It has a role as an EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor, a mouse metabolite and a human metabolite. It is a saturated fatty acyl-L-carnitine, a long-chain fatty acyl-L-carnitine and an O-palmitoylcarnitine. It is functionally related to a hexadecanoic acid. — ChEBI

IUPAC name: (3R)-3-hexadecanoyloxy-4-(trimethylazaniumyl)butanoate

Molecular formula: C23H45NO4
Molecular weight: 399.6 g/mol
Exact mass: 399.33485892 Da
XLogP3: 7.7
Topological polar surface area: 66.4 Å²
Hydrogen-bond donors: 0
Hydrogen-bond acceptors: 4
Covalent units: 1
Defined stereocentres: 1

Also known as

RefChem:858421L-PalmitoylcarnitinePalmitoyl-L-carnitineO-palmitoyl-L-carnitineHexadecanoyl-L-carnitineL-Carnitine palmitoyl esterhexadecanoylcarnitinePalmityl-L-carnitine

16 more reported names

palmitoyl L-carnitine(R)-3-(Palmitoyloxy)-4-(trimethylammonio)butanoateO-hexadecanoyl-R-carnitineHexadecenoyl carnitine(3R)-3-(hexadecanoyloxy)-4-(trimethylazaniumyl)butanoateCHEBI:17490L(-)-PalmitylcarnitinePalmitoyl-(-)-carnitinePalmitoyl carnitine, (-)-O-hexadecanoyl-(R)-carnitine(3R)-3-hexadecanoyloxy-4-(trimethylammonio)butanoate1G38O5K038Ammonium, (3-carboxy-2-hydroxypropyl)trimethyl-, hydroxide, inner salt, palmitate, L-(3R)-3-palmitoyloxy-4-(trimethylammonio)butanoateD-PalmitylcarnitinePalmitoyl d-carnitine

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:17490
ChEMBL:CHEMBL3392050
EPA DTXSID:DTXSID101019091
PubMed:29968805

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for PALMITOYL CARNITINE

INCI name

PALMITOYL CARNITINE

Description

1-Propanaminium, 3-carboxy-2-(1-oxohexadecyloxy)-N,N,N-trimethyl-, hydroxide, inner salt

Record provenance

Inventory reference: 78424
Imported identity: PALMITOYL CARNITINE
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for PALMITOYL CARNITINE

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Key data

CAS

1935-18-8 / 2364-67-2

- / -

Restriction

—

Function

SKIN CONDITIONING: Maintaining the skin in good condition.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#18712 · PALMITOYL CARNITINE

Records sharing a CAS or EC identity

ACETYL MANDELIC ACID AMMONIUM MONOFLUOROPHOSPHATE ATTAPULGITE BAICALIN BETULA ALBA OIL BUTETH-3 CARBOXYLIC ACID CARAPA GUAIANENSIS SEED OIL CARAPA GUAIANENSIS SEED POWDER

Ingredients with overlapping formulation functions

PALMITAMIDOHEXADECANEDIOLSKIN CONDITIONING

PALMITAMIDOPROPYL BETAINEANTISTATIC, CLEANSING, HAIR CONDITIONING, SKIN CONDITIONING, SURFACTANT - CLEANSING, SURFACTANT - F…

PALMITOYL ARGININEHAIR CONDITIONING, SKIN CONDITIONING

PALMITOYL CAMELLIA SINENSIS EXTRACTSKIN CONDITIONING

PALMITOYL COCOA SEED EXTRACTANTIOXIDANT, SKIN CONDITIONING

PALMITOYL DECAPEPTIDE-21SKIN CONDITIONING

PALMITOYL DIPEPTIDE-10SKIN CONDITIONING

PALMITOYL DIPEPTIDE-13SKIN CONDITIONING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How PALMITOYL CARNITINE appears in the CosIng inventory

The CosIng inventory lists PALMITOYL CARNITINE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

PALMITOYL CARNITINE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

PALMITOYL CARNITINE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, PALMITOYL CARNITINE carries the following function designation(s):

SKIN CONDITIONING

CAS 1935-18-8 / 2364-67-2 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for PALMITOYL CARNITINE

This page reproduces the CosIng inventory entry for PALMITOYL CARNITINE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research PALMITOYL CARNITINE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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