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InventoryRef 5814015/10/2010

PALMITOYL ARGININE

L-Arginine, N(2)-hexadecanoyl-

PALMITOYL ARGININE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

Chemical identity and properties

PubChem 2D chemical structure for CAS 58725-47-6
CAS 58725-47-6PubChem CID 11223678

Palmitoyl Arginine

The panel concluded that the 115 amino acid alkyl amides listed below are safe in the present practices of use and concentration in cosmetics, when formulated to be non-irritating...Palmitoyl Arginine... Cosmetic Ingredient Review (CIR)

IUPAC name
(2S)-5-(diaminomethylideneamino)-2-(hexadecanoylamino)pentanoic acid
Molecular formula
C22H44N4O3
Molecular weight
412.6 g/mol
Exact mass
412.34134128 Da
XLogP3
5.7
Topological polar surface area
131.0 Ų
Hydrogen-bond donors
4
Hydrogen-bond acceptors
4
Covalent units
1
Defined stereocentres
1

Also known as

N2-(1-Oxohexadecyl)-L-arginineEINECS 261-410-5N-Palmitoyl-L-arginineUNII-2F8GZ263AP2F8GZ263APAMISAFE AP-01L-Arginine, N2-(1-oxohexadecyl)-RefChem:169733
3 more reported names
PALMITOYL ARGININE [INCI]mono-Nalpha-palmitoyl-L-arginineDB-326986

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for PALMITOYL ARGININE

INCI name

PALMITOYL ARGININE

Description

L-Arginine, N(2)-hexadecanoyl-

Record provenance

Inventory reference
58140
Imported identity
PALMITOYL ARGININE
Source update
15/10/2010
European Commission CosIng source notes

Key data

Restriction
Function
HAIR CONDITIONING
Enhancing the appearance and feel of hair. Leaving the hair easy to comb, supple, soft and shiny and/or imparting volume, lightness, gloss, texture, etc.
SKIN CONDITIONING
Maintaining the skin in good condition.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

Ingredients with overlapping formulation functions

Additional official and scientific sources

11 external databases to check this identity in

How PALMITOYL ARGININE appears in the CosIng inventory

The CosIng inventory lists PALMITOYL ARGININE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

PALMITOYL ARGININE is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

PALMITOYL ARGININE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, PALMITOYL ARGININE carries the following function designation(s):

CAS 58725-47-6 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

Source note for PALMITOYL ARGININE

This page reproduces the CosIng inventory entry for PALMITOYL ARGININE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research PALMITOYL ARGININE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

Tools & next steps

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