What does the restriction note for SODIUM THIOGLYCOLATE mean?

The restriction field for SODIUM THIOGLYCOLATE reads: III/2a. This is the restriction note from the CosIng inventory. For authoritative conditions and limits, always refer to the linked annex entries.

What function does SODIUM THIOGLYCOLATE serve in cosmetics?

According to the EU CosIng inventory, SODIUM THIOGLYCOLATE carries the following function designation(s): ANTIOXIDANT, DEPILATORY, HAIR WAVING OR STRAIGHTENING, REDUCING.

What other records share CAS 367-51-1?

CAS 367-51-1 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains SODIUM THIOGLYCOLATE?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 3810215/10/2010

SODIUM THIOGLYCOLATE

Sodium mercaptoacetate

SODIUM THIOGLYCOLATE is linked to 1 EU annex record on this page. Inventory note: III/2a.

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Regulatory evidence by market

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Market	Evidence status	Records	Source language
European Union	Evidence linked Restricted entry found Open this evidence	1	English and EU languages
Great Britain	Source mapped Official source mapped; ingredient rule not imported	0	English
Canada	Source mapped Official source mapped; ingredient rule not imported	0	English and French
New Zealand	Source mapped Official source mapped; ingredient rule not imported	0	English
ASEAN	Source mapped Official source mapped; ingredient rule not imported	0	English and national languages
China	Source mapped Official source mapped; ingredient rule not imported	0	Chinese with selected English material
Japan	Source mapped Official source mapped; ingredient rule not imported	0	Japanese; official English translation available
South Korea	Source mapped Official source mapped; ingredient rule not imported	0	Korean with some English names
United States	Source mapped Official source mapped; ingredient rule not imported	0	English
Australia	Source mapped Official source mapped; ingredient rule not imported	0	English
Brazil	Source mapped Official source mapped; ingredient rule not imported	0	Portuguese with INCI crosswalks
India	Source mapped Official source mapped; ingredient rule not imported	0	English and Hindi
Saudi Arabia	Source mapped Official source mapped; ingredient rule not imported	0	Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 367-51-1

CAS 367-51-1PubChem CID 23690444

Sodium Thioglycolate

Sodium thioglycolate is an organic sodium salt having thioglycolate(1) as the counterion. It has a role as a reducing agent. It contains a thioglycolate(1-). — ChEBI

IUPAC name: sodium 2-sulfanylacetate

Molecular formula: C2H3NaO2S
Molecular weight: 114.10 g/mol
Exact mass: 113.97514479 Da
Topological polar surface area: 41.1 Å²
Hydrogen-bond donors: 1
Hydrogen-bond acceptors: 3
Covalent units: 2
Defined stereocentres: 0

Also known as

Sodium mercaptoacetateMercaptoacetic acid sodium saltThioglycolate sodiumSodium thioglycollateMercaptoacetic acid, sodium saltsodium sulfanylacetateSodium 2-mercatoethanoateThioglycollic acid, sodium salt

16 more reported names

Acetic acid, mercapto-, monosodium saltThioglycolic acid, sodium saltCCRIS 4874USAF EK-5199EINECS 206-696-4EINECS 253-166-3Thioglycolic acid sodium saltUNII-D94M78P69VCHEBI:86481SODIUM THIOGLYCOLATE [II]SODIUM THIOGLYCOLATE [MI]EC 206-696-4SODIUM THIOGLYCOLATE (II)Sodium 2sulfanylacetateSodium 2mercatoethanoateTHIOGLYCOLATESODIUM

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:86481
EPA DTXSID:DTXSID3026142

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for SODIUM THIOGLYCOLATE

INCI name

SODIUM THIOGLYCOLATE

Description

Sodium mercaptoacetate

Record provenance

Inventory reference: 38102
Imported identity: SODIUM THIOGLYCOLATE
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for SODIUM THIOGLYCOLATE

Annex III Restriction reference

Entry 2a

THIOGLYCOLIC ACID

CAS: 68-11-1

EC: 200-677-4

Key data

CAS

367-51-1

206-696-4

Restriction

III/2a

Function

ANTIOXIDANT: Inhibiting reactions promoted by oxygen, thus avoiding oxidation and rancidity.
DEPILATORY: Breaking down the mechanical strength of hair fibers so that they can be removed by mild scraping/rubbing.
HAIR WAVING OR STRAIGHTENING: Modifying the chemical structure of the hair, allowing it to be set in the style required (permanent waves or hair straightening).
REDUCING: Changing the chemical nature of another ingredient by adding hydrogen (or removing oxygen).

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#27065 · SODIUM THIOGLYCOLATE

Ingredients with overlapping formulation functions

PROPANEDIOL ROSINATESDEPILATORY, FILM FORMING

ROSIN GLYCERIDESANTIMICROBIAL; DEPILATORY; FILM FORMING

ROSIN/FORMALDEHYDE COPOLYMERDEPILATORY

SODIUM SULFIDEDEPILATORY

STRONTIUM SULFIDEDEPILATORY

STRONTIUM THIOGLYCOLATEDEPILATORY, HAIR WAVING OR STRAIGHTENING, REDUCING

STYRENE/METHYLSTYRENE COPOLYMERBINDING, DEPILATORY

THIOGLYCERINDEPILATORY, HAIR WAVING OR STRAIGHTENING, KERATOLYTIC, REDUCING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How SODIUM THIOGLYCOLATE appears in the CosIng inventory

The CosIng inventory lists SODIUM THIOGLYCOLATE as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.

SODIUM THIOGLYCOLATE is also tagged with 4 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

SODIUM THIOGLYCOLATE appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

The restriction field for SODIUM THIOGLYCOLATE reads: "III/2a". This is the restriction note recorded in the CosIng inventory for this ingredient. For authoritative conditions and limits, always refer to the linked annex entries above.

According to the EU CosIng inventory, SODIUM THIOGLYCOLATE carries the following function designation(s):

CAS 367-51-1 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for SODIUM THIOGLYCOLATE

This page combines the CosIng inventory entry for SODIUM THIOGLYCOLATE with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research SODIUM THIOGLYCOLATE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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