PHLOROGLUCINOL
1,3,5-Benzenetriol
PHLOROGLUCINOL is linked to 1 EU annex record on this page. Inventory note: II/1253.
Regulatory evidence by market
This matrix separates verified ingredient rules from sources that are mapped but not yet imported. No imported rule does not mean the ingredient is permitted.
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| Market | Evidence status | Records | Source language |
|---|---|---|---|
| European Union | Evidence linked Prohibited entry found Open this evidence | 1 | English and EU languages |
| Great Britain | Evidence linked Prohibited Open this evidence | 1 | English |
| Canada | Source mapped Official source mapped; ingredient rule not imported | 0 | English and French |
| New Zealand | Evidence linked Prohibited Open this evidence | 1 | English |
| ASEAN | Evidence linked Prohibited Open this evidence | 1 | English and national languages |
| China | Evidence linked Prohibited Open this evidence | 1 | Chinese with selected English material |
| Japan | Source mapped Official source mapped; ingredient rule not imported | 0 | Japanese; official English translation available |
| South Korea | Evidence linked Prohibited Open this evidence | 1 | Korean with some English names |
| United States | Source mapped Official source mapped; ingredient rule not imported | 0 | English |
| Australia | Source mapped Official source mapped; ingredient rule not imported | 0 | English |
| Brazil | Evidence linked Prohibited Open this evidence | 1 | Portuguese with INCI crosswalks |
| India | Evidence linked Prohibited Open this evidence | 1 | English and Hindi |
| Saudi Arabia | Evidence linked Prohibited Open this evidence | 1 | Arabic and English |
Chemical identity and properties
Phloroglucinol
Phloroglucinol is a benzenetriol with hydroxy groups at position 1, 3 and 5. It has a role as an algal metabolite. It is a phenolic donor and a benzenetriol. — ChEBI
- IUPAC name
- benzene-1,3,5-triol
- Molecular formula
- C6H6O3
- Molecular weight
- 126.11 g/mol
- Exact mass
- 126.031694049 Da
- XLogP3
- 0.2
- Topological polar surface area
- 60.7 Ų
- Hydrogen-bond donors
- 3
- Hydrogen-bond acceptors
- 3
- Covalent units
- 1
- Defined stereocentres
- 0
Also known as
16 more reported names
External database identifiers
- ChEBI:CHEBI:16204
- ChEMBL:CHEMBL473159
- EPA DTXSID:DTXSID9048354
- PubMed:26054450
- PubMed:23800587
- PubMed:23178381
- PubMed:23013382
- PubMed:22978662
- PubMed:22978223
- PubMed:22938149
- PubMed:22934600
- PubMed:22927079
- PubMed:22896828
- PubMed:22889530
- PubMed:22868169
Evidence from additional scientific databases
NIH PubChem PUG-View
Attributed physical-property, hazard, environmental and use annotations.
- LogP: 0.16 Source: Human Metabolome Database (HMDB)
- Melting Point: 218.5 °C Source: Human Metabolome Database (HMDB)
- Physical Description: White solid; Discolored by light; [Merck Index] White or cream colored powder; [MSDSonline] Crystallizes in anhydrous or dihydrate form; Sweet tasting crystals; [Ullmann] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Physical Description: Solid Source: Human Metabolome Database (HMDB)
- Solubility: 10.6 mg/mL at 20 °C Source: Human Metabolome Database (HMDB)
- Vapor Pressure: 0.00016 [mmHg] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Note: This chemical does not meet GHS hazard criteria for 1.9% (2 of 108) of reports. Source: European Chemicals Agency (ECHA)
- Signal: Warning Source: European Chemicals Agency (ECHA)
- GHS Hazard Statements: H315 (81.5%): Causes skin irritation [Warning Skin corrosion/irritation]; H317 (41.7%): May cause an allergic skin reaction [Warning Sensitization, Skin]; H319 (81.5%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H335 (81.5%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]; H341 (11.1%): Suspected of causing genetic defects [Warning Germ cell mutagenicity]; H361 (11.1%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]; H412 (12%): Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard] Source: European Chemicals Agency (ECHA)
- Precautionary Statement Codes: P203, P261, P264, P264+P265, P271, P272, P273, P280, P302+P352, P304+P340, P305+P351+P338, P318, P319, P321, P332+P317, P333+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
- ECHA C&L Notifications Summary: Aggregated GHS information provided per 108 reports by companies from 23 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Reported as not meeting GHS hazard criteria per 2 of 108 reports by companies.; There are 22 notifications provided by 106 of 108 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
- Cosmetic Ingredient Review Conclusion: On the basis of the available data, the CIR Panel cannot conclude that Phloroglucinol is safe for use in cosmetic products until the appropriate safety data have been obtained and evaluated. Source: Cosmetic Ingredient Review (CIR)
- Cosmetic Ingredient Review Finding(s): Ingredients for which the data are insufficient and their use in cosmetics is not supported Source: Cosmetic Ingredient Review (CIR)
- Cosmetic Ingredient Review Link: CIR ingredient: Phloroglucinol Source: Cosmetic Ingredient Review (CIR)
- Sources/Uses: Used to decalcify bones, to make pharmaceuticals and dyes, to preserve cut flowers, and to dye and print textiles; [Hawley] Used in diazo-type printing, cosmetics (antioxidant), hair colorants, chemical reagents, cloud seeding, tree and shrub rooting, and pharmaceuticals (antispasmodic); [Merck Index] Isolated from bark of fruit trees in 1855; [Ullmann] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Industrial Processes with risk of exposure: Textiles (Printing, Dyeing, or Finishing) [Category: Industry] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record
Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.
Additional source coverage and match status
| Source | Result | Checked |
|---|---|---|
| NIH PubChem PUG-View | Exact match | 2026-08-31 |
A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
Inventory details for PHLOROGLUCINOL
INCI name
PHLOROGLUCINOL
Description
1,3,5-Benzenetriol
Record provenance
- Inventory reference
- 36542
- Imported identity
- PHLOROGLUCINOL
- Source update
- 15/10/2010
Annex records for PHLOROGLUCINOL
1,3,5-Trihydroxybenzene (Phloroglucinol) and its salts, when used as a substance in hair dye produc…
Key data
- HAIR DYEING
- Imparting color to hair. Hair dyeing preparations may be temporary, semi-permanent, or permanent, depending on the length of time the colorant remains on the hair.
Official EU ingredient-name evidence
The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.
Related inventory evidence
Ingredients with overlapping formulation functions
Additional official and scientific sources
11 external databases to check this identity in
Each link searches that source for this identity. What each source is, and its legal weight
How PHLOROGLUCINOL appears in the CosIng inventory
The CosIng inventory lists PHLOROGLUCINOL as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.
PHLOROGLUCINOL is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.
Frequently asked questions
Source note for PHLOROGLUCINOL
This page combines the CosIng inventory entry for PHLOROGLUCINOL with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.
Use this inventory page to research PHLOROGLUCINOL and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.
Tools & next steps
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