What does the restriction note for PEG-3,2',2'-DI-P-PHENYLENEDIAMINE mean?

The restriction field for PEG-3,2',2'-DI-P-PHENYLENEDIAMINE reads: II/1234. This is the restriction note from the CosIng inventory. For authoritative conditions and limits, always refer to the linked annex entries.

What other records share CAS 144644-13-3?

CAS 144644-13-3 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains PEG-3,2',2'-DI-P-PHENYLENEDIAMINE?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 3612915/10/2010

PEG-3,2',2'-DI-P-PHENYLENEDIAMINE

PEG-3,2',2'-DI-P-PHENYLENEDIAMINE is linked to 1 EU annex record on this page. Inventory note: II/1234.

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Regulatory evidence by market

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Market	Evidence status	Records	Source language
European Union	Evidence linked Prohibited entry found Open this evidence	1	English and EU languages
Great Britain	Evidence linked Prohibited Open this evidence	1	English
Canada	Source mapped Official source mapped; ingredient rule not imported	0	English and French
New Zealand	Evidence linked Prohibited Open this evidence	1	English
ASEAN	Evidence linked Prohibited Open this evidence	1	English and national languages
China	Evidence linked Prohibited Open this evidence	1	Chinese with selected English material
Japan	Source mapped Official source mapped; ingredient rule not imported	0	Japanese; official English translation available
South Korea	Evidence linked Prohibited Open this evidence	1	Korean with some English names
United States	Source mapped Official source mapped; ingredient rule not imported	0	English
Australia	Source mapped Official source mapped; ingredient rule not imported	0	English
Brazil	Evidence linked Prohibited Open this evidence	1	Portuguese with INCI crosswalks
India	Evidence linked Prohibited Open this evidence	1	English and Hindi
Saudi Arabia	Evidence linked Prohibited Open this evidence	1	Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 144644-13-3

CAS 144644-13-3PubChem CID 22617270

1,8-Bis(2,5-diaminophenoxy)-3,6-dioxaoctane tetrahydrochloride

IUPAC name: 2-[2-[2-[2-(2,5-diaminophenoxy)ethoxy]ethoxy]ethoxy]benzene-1,4-diamine;tetrahydrochloride

Molecular formula: C18H30Cl4N4O4
Molecular weight: 508.3 g/mol
Exact mass: 508.099166 Da
Topological polar surface area: 141.0 Å²
Hydrogen-bond donors: 8
Hydrogen-bond acceptors: 8
Covalent units: 5
Defined stereocentres: 0

Also known as

RefChem:2217462,2'-(((Ethane-1,2-diylbis(oxy))bis(ethane-2,1-diyl))bis(oxy))bis(benzene-1,4-diamine) tetrahydrochloride2,2'-[Ethane-1,2-diylbis(oxyethane-2,1-diyloxy)]di(benzene-1,4-diamine)--hydrogen chloride (1/4)

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External database identifiers

EPA DTXSID:DTXSID20892449

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for PEG-3,2',2'-DI-P-PHENYLENEDIAMINE

INCI name

PEG-3,2',2'-DI-P-PHENYLENEDIAMINE

Record provenance

Inventory reference: 36129
Imported identity: PEG-3,2',2'-DI-P-PHENYLENEDIAMINE
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for PEG-3,2',2'-DI-P-PHENYLENEDIAMINE

Annex II Restriction reference

Entry 1234

PEG-3,2',2'-di-p-phenylenediamine

CAS: 144644-13-3

Key data

CAS

144644-13-3

—

Restriction

II/1234

Function

HAIR DYEING: Imparting color to hair. Hair dyeing preparations may be temporary, semi-permanent, or permanent, depending on the length of time the colorant remains on the hair.

Ingredients with overlapping formulation functions

P-PHENYLENEDIAMINE HCLHAIR DYEING

P-PHENYLENEDIAMINE HYDROXYETHYL ETHERHAIR DYEING

P-PHENYLENEDIAMINE SULFATEHAIR DYEING

PEG-3 2,2'-DI-P-PHENYLENEDIAMINEHAIR DYEING

PHENYL METHYL PYRAZOLONEHAIR DYEING

PHLOROGLUCINOLHAIR DYEING

PICRAMIC ACIDHAIR DYEING

PIGMENT BLUE 15HAIR DYEING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How PEG-3,2',2'-DI-P-PHENYLENEDIAMINE appears in the CosIng inventory

The CosIng inventory lists PEG-3,2',2'-DI-P-PHENYLENEDIAMINE as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.

PEG-3,2',2'-DI-P-PHENYLENEDIAMINE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

PEG-3,2',2'-DI-P-PHENYLENEDIAMINE appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

The restriction field for PEG-3,2',2'-DI-P-PHENYLENEDIAMINE reads: "II/1234". This is the restriction note recorded in the CosIng inventory for this ingredient. For authoritative conditions and limits, always refer to the linked annex entries above.

According to the EU CosIng inventory, PEG-3,2',2'-DI-P-PHENYLENEDIAMINE carries the following function designation(s):

HAIR DYEING

CAS 144644-13-3 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for PEG-3,2',2'-DI-P-PHENYLENEDIAMINE

This page combines the CosIng inventory entry for PEG-3,2',2'-DI-P-PHENYLENEDIAMINE with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research PEG-3,2',2'-DI-P-PHENYLENEDIAMINE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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