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InventoryRef 3391012/07/2019

EUGENOL

Phenol, 2-methoxy-4-(2-propenyl)-

EUGENOL is linked to 1 EU annex record on this page. Inventory note: III/71.

Regulatory evidence by market

This matrix separates verified ingredient rules from sources that are mapped but not yet imported. No imported rule does not mean the ingredient is permitted.

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MarketEvidence statusRecordsSource language
European UnionEvidence linked
Restricted entry found
Open this evidence
1English and EU languages
Great BritainEvidence linked
Restricted
Open this evidence
1English
CanadaSource mapped
Official source mapped; ingredient rule not imported
0English and French
New ZealandEvidence linked
Restricted
Open this evidence
1English
ASEANSource mapped
Official source mapped; ingredient rule not imported
0English and national languages
ChinaSource mapped
Official source mapped; ingredient rule not imported
0Chinese with selected English material
JapanSource mapped
Official source mapped; ingredient rule not imported
0Japanese; official English translation available
South KoreaSource mapped
Official source mapped; ingredient rule not imported
0Korean with some English names
United StatesSource mapped
Official source mapped; ingredient rule not imported
0English
AustraliaSource mapped
Official source mapped; ingredient rule not imported
0English
BrazilSource mapped
Official source mapped; ingredient rule not imported
0Portuguese with INCI crosswalks
IndiaEvidence linked
Restricted
Open this evidence
1English and Hindi
Saudi ArabiaEvidence linked
Restricted
Open this evidence
1Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 97-53-0
CAS 97-53-0PubChem CID 3314

Eugenol

Eugenol is a phenylpropanoid formally derived from guaiacol with an allyl chain substituted para to the hydroxy group. It is a major component of clove essential oil, and exhibits antibacterial, analgesic and antioxidant properties. It has been widely used in dentistry to treat toothache and pulpitis. It has a role as a sensitiser, a volatile oil component, an antibacterial agent, an analgesic, an antineoplastic agent, a flavouring agent, an EC 1.4.3.4 (monoamine oxidase) inhibitor, a voltage-gated sodium channel blocker, an anaesthetic, a radical scavenger, an allergen, an anti-inflammatory agent, an apoptosis inducer, a NF-kappaB inhibitor and a human blood serum metabolite. It is an alkenylbenzene, a monomethoxybenzene, a phenylpropanoid and a member of phenols. It is functionally related to a guaiacol. ChEBI

IUPAC name
2-methoxy-4-prop-2-enylphenol
Molecular formula
C10H12O2
Molecular weight
164.20 g/mol
Exact mass
164.083729621 Da
XLogP3
2.0
Topological polar surface area
29.5 Ų
Hydrogen-bond donors
1
Hydrogen-bond acceptors
2
Covalent units
1
Defined stereocentres
0

Also known as

4-Allyl-2-methoxyphenol4-AllylguaiacolEugenic acidAllylguaiacolCaryophyllic acidp-Eugenolp-AllylguaiacolEngenol
16 more reported names
2-Methoxy-4-allylphenolPhenol, 2-methoxy-4-(2-propenyl)-5-Allylguaiacol2-Methoxy-4-(2-propenyl)phenolSynthetic eugenol1,3,4-Eugenol4-Allylcatechol-2-methyl ether1-Hydroxy-2-methoxy-4-allylbenzene2-methoxy-4-(prop-2-en-1-yl)phenol2-Methoxy-1-hydroxy-4-allylbenzene4-Allyl-1-hydroxy-2-methoxybenzenebioxedaPhenol, 4-allyl-2-methoxy-FEMA No. 24674-Allylcatechol 2-methyl ether4-Hydroxy-3-methoxyallylbenzene
External database identifiers

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for EUGENOL

INCI name

EUGENOL

INN name

eugenol

Ph. Eur. name

eugenolum

Description

Phenol, 2-methoxy-4-(2-propenyl)-

Record provenance

Inventory reference
33910
Imported identity
EUGENOL
Source update
12/07/2019
European Commission CosIng source notes
Annex III Restriction reference
Entry 71

Eugenol

CAS: 97-53-0
EC: 202-589-1

Key data

Restriction
III/71
Function
DENATURANT
Rendering cosmetics unpalatable. Mostly added to cosmetics containing ethyl alcohol to make it unsuitable for ingestion.
PERFUMING
Used for perfume and aromatic raw materials.
TONIC
Producing a feeling of well-being on skin and hair.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

Declared fragrance allergen

This substance is on the EU list of fragrance allergens that must be named individually in the ingredient list, rather than being covered by the word "parfum", once it exceeds 0.001% in a leave-on product or 0.01% in a rinse-off product.

Declaration is a labelling duty under Article 19, not a restriction on use. See the allergen record

Ingredients with overlapping formulation functions

Additional official and scientific sources

11 external databases to check this identity in

How EUGENOL appears in the CosIng inventory

The CosIng inventory lists EUGENOL as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.

EUGENOL is also tagged with 3 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

EUGENOL appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

The restriction field for EUGENOL reads: "III/71". This is the restriction note recorded in the CosIng inventory for this ingredient. For authoritative conditions and limits, always refer to the linked annex entries above.

According to the EU CosIng inventory, EUGENOL carries the following function designation(s):

CAS 97-53-0 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

Source note for EUGENOL

This page combines the CosIng inventory entry for EUGENOL with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research EUGENOL and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

Tools & next steps

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