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CAS 3734-33-6 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

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InventoryRef 3318815/10/2010

DENATONIUM BENZOATE

Denatonium benzoate

DENATONIUM BENZOATE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 3734-33-6

CAS 3734-33-6PubChem CID 19518

Denatonium Benzoate

IUPAC name: benzyl-[2-(2,6-dimethylanilino)-2-oxoethyl]-diethylazanium benzoate

Molecular formula: C28H34N2O3
Molecular weight: 446.6 g/mol
Exact mass: 446.25694295 Da
Topological polar surface area: 69.2 Å²
Hydrogen-bond donors: 1
Hydrogen-bond acceptors: 3
Covalent units: 2
Defined stereocentres: 0

Also known as

BitrexLidocaine benzyl benzoateAversionTHS-839AnisprayGoriBenzoato de denatonioBenzoate de denatonium

16 more reported names

Denatonium benzoate anhydrousDenatonii benzoasWIN 16568Lignocaine benzyl benzoateM5BA6GAF1OBenzyldiethyl((2,6-xylylcarbamoyl)methyl)ammonium benzoateNSC-157658ECX-95BYWIN-16568Benzyldiethyl[(2,6-xylylcarbamoyl)methyl]ammonium benzoateRefChem:131793223-095-24YK5Z54AT2Denatonium benzoate monohydrateLidocaine benzyl benzoate hydrateDenatonium (benzoate)

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEMBL:CHEMBL1371493
EPA DTXSID:DTXSID8034376
PubMed:29070885
PubMed:18003792
PubMed:9402622

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for DENATONIUM BENZOATE

INCI name

DENATONIUM BENZOATE

INN name

denatonium benzoate

Description

Denatonium benzoate

Record provenance

Inventory reference: 33188
Imported identity: DENATONIUM BENZOATE
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for DENATONIUM BENZOATE

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Key data

CAS

3734-33-6

223-095-2

Restriction

—

Function

DENATURANT: Rendering cosmetics unpalatable. Mostly added to cosmetics containing ethyl alcohol to make it unsuitable for ingestion.
FRAGRANCE: Imparting an odour or taste. Creating a perceivable pleasant smell and/or masking a bad smell.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#8312 · DENATONIUM BENZOATE

Ingredients with overlapping formulation functions

CHLOROTHYMOLANTIMICROBIAL, ANTIPLAQUE, DENATURANT, DEODORANT, ORAL CARE

CINNAMALDENATURANT, FLAVOURING, PERFUMING

CINNAMOMUM CASSIA LEAF OILDENATURANT, FRAGRANCE, PERFUMING

COAL TARANTI-SEBORRHEIC, ANTIMICROBIAL, DENATURANT

DENATONIUM SACCHARIDEDENATURANT

DIETHYL PHTHALATEDENATURANT, FILM FORMING, FRAGRANCE, HAIR CONDITIONING, PLASTICISER, SOLVENT

EUCALYPTOLDENATURANT, PERFUMING, TONIC

EUGENOLDENATURANT, PERFUMING, TONIC

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How DENATONIUM BENZOATE appears in the CosIng inventory

The CosIng inventory lists DENATONIUM BENZOATE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

DENATONIUM BENZOATE is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

DENATONIUM BENZOATE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, DENATONIUM BENZOATE carries the following function designation(s):

CAS 3734-33-6 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for DENATONIUM BENZOATE

This page reproduces the CosIng inventory entry for DENATONIUM BENZOATE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research DENATONIUM BENZOATE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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