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InventoryRef 3522815/10/2010

MENTHOL

Cyclohexanol, 5-methyl-2-(1-methylethyl)-

MENTHOL is linked to 1 EU annex record on this page.

Regulatory evidence by market

This matrix separates verified ingredient rules from sources that are mapped but not yet imported. No imported rule does not mean the ingredient is permitted.

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MarketEvidence statusRecordsSource language
European UnionEvidence linked
Restricted entry found
Open this evidence
1English and EU languages
Great BritainSource mapped
Official source mapped; ingredient rule not imported
0English
CanadaSource mapped
Official source mapped; ingredient rule not imported
0English and French
New ZealandSource mapped
Official source mapped; ingredient rule not imported
0English
ASEANSource mapped
Official source mapped; ingredient rule not imported
0English and national languages
ChinaSource mapped
Official source mapped; ingredient rule not imported
0Chinese with selected English material
JapanSource mapped
Official source mapped; ingredient rule not imported
0Japanese; official English translation available
South KoreaSource mapped
Official source mapped; ingredient rule not imported
0Korean with some English names
United StatesSource mapped
Official source mapped; ingredient rule not imported
0English
AustraliaSource mapped
Official source mapped; ingredient rule not imported
0English
BrazilSource mapped
Official source mapped; ingredient rule not imported
0Portuguese with INCI crosswalks
IndiaEvidence linked
Restricted
Open this evidence
1English and Hindi
Saudi ArabiaEvidence linked
Restricted
Open this evidence
1Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 1490-04-6
CAS 1490-04-6CAS 15356-70-4PubChem CID 1254

Menthol

P-menthan-3-ol is any secondary alcohol that is one of the eight possible diastereoisomers of 5-methyl-2-(propan-2-yl)cyclohexan-1-ol. It has a role as a volatile oil component. It is a p-menthane monoterpenoid and a secondary alcohol. ChEBI

IUPAC name
5-methyl-2-propan-2-ylcyclohexan-1-ol
Molecular formula
C10H20O
Molecular weight
156.26 g/mol
Exact mass
156.151415257 Da
XLogP3
3.0
Topological polar surface area
20.2 Ų
Hydrogen-bond donors
1
Hydrogen-bond acceptors
1
Covalent units
1
Defined stereocentres
0

Also known as

2-Isopropyl-5-methylcyclohexanolMenthyl alcoholMentholumCaswell No. 540Mineral ice5-Methyl-2-(1-methylethyl)cyclohexanol3-Hydroxy-p-menthane2-Isopropyl-5-methylcyclohexan-1-ol
16 more reported names
CCRIS 9231EINECS 216-074-4EPA Pesticide Chemical Code 051601HSDB 593AI3-08161Therapeutic mineral iceMENTHOL, UNSPECIFIED FORMEC 216-074-41-Methyl-4-isopropyl-3-cyclohexanolFisherman's friend lozengesUNII-L7T10EIP3ABOHENAORefChem:6462MENTHOL (II)MENTHOL (MART.)MENTHOL, UNSPECIFIED
External database identifiers

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 2216-51-5
CAS 2216-51-5PubChem CID 16666

(-)-Menthol

(-)-menthol is a p-menthan-3-ol which has (1R,2S,5R)-stereochemistry. It is the most common naturally occurring enantiomer. It has a role as an antitussive, an antispasmodic drug and an antipruritic drug. It is an enantiomer of a (+)-menthol. ChEBI

IUPAC name
(1R,2S,5R)-5-methyl-2-propan-2-ylcyclohexan-1-ol
Molecular formula
C10H20O
Molecular weight
156.26 g/mol
Exact mass
156.151415257 Da
XLogP3
3.0
Topological polar surface area
20.2 Ų
Hydrogen-bond donors
1
Hydrogen-bond acceptors
1
Covalent units
1
Defined stereocentres
3

Also known as

l-MentholLevomentholl-(-)-Menthol(-)-Menthyl alcoholLevomentholumU.S.P. Menthol(1R)-(-)-Menthol(-)-(1R,3R,4S)-Menthol
16 more reported names
D-(-)-Menthol(-)-trans-p-Menthan-cis-ollevomentol(1R,2S,5R)-5-methyl-2-(propan-2-yl)cyclohexan-1-olMenthol, (1R,3R,4S)-(-)-(1R,3R,4S)-(-)-MENTHOLBZ1R15MTK7(1R-(1-alpha,2-beta,5-alpha))-5-Methyl-2-(1-methylethyl)cyclohexanolCHEBI:15409(1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexanolNSC-62788NPO-11(1alpha,2beta,5alpha)-5-methyl-2(1-methylethyl)cyclohexanolFEMA NO. 2665, (-)-levomentoloRefChem:1049117
External database identifiers

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for MENTHOL

INCI name

MENTHOL

Ph. Eur. name

mentholum

Description

Cyclohexanol, 5-methyl-2-(1-methylethyl)-

Record provenance

Inventory reference
35228
Imported identity
MENTHOL
Source update
15/10/2010
European Commission CosIng source notes
Annex III Identified ingredient
Entry 338

Menthol

CAS: 89-78-1 / 1490-04-6 / 2216-51-5 / 15356-60-2
EC: 201-939-0/ 216-074-4/ 218-690-9/ 239-387-8

Key data

CAS
1490-04-6 / 2216-51-5 / 89-78-1 / 15356-70-4
EC
216-074-4 / 218-690-9 / 201-939-0 / 239-388-3
Restriction
Function
DENATURANT
Rendering cosmetics unpalatable. Mostly added to cosmetics containing ethyl alcohol to make it unsuitable for ingestion.
FRAGRANCE
Imparting an odour or taste. Creating a perceivable pleasant smell and/or masking a bad smell.
REFRESHING
Imparting a pleasant freshness to the skin.
SOOTHING
Lightening discomfort of the skin or of the scalp.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

Ingredients with overlapping formulation functions

Additional official and scientific sources

11 external databases to check this identity in

How MENTHOL appears in the CosIng inventory

The CosIng inventory lists MENTHOL as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.

MENTHOL is also tagged with 4 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

MENTHOL appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

According to the EU CosIng inventory, MENTHOL carries the following function designation(s):

CAS 1490-04-6 / 2216-51-5 / 89-78-1 / 15356-70-4 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

Source note for MENTHOL

This page combines the CosIng inventory entry for MENTHOL with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research MENTHOL and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

Tools & next steps

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