CYCLOMETHICONE
Cyclomethicone is a generic name for a mixture of cyclic dimethyl polysiloxane compounds that conform to the formula, where n has a value between 4 and 6.
CYCLOMETHICONE is linked to 1 EU annex record on this page. Inventory note: II/1388 (Only when Cyclomethicone contains D4).
Regulatory evidence by market
This matrix separates verified ingredient rules from sources that are mapped but not yet imported. No imported rule does not mean the ingredient is permitted.
Swipe or scroll horizontally to see every column.
| Market | Evidence status | Records | Source language |
|---|---|---|---|
| European Union | Evidence linked Prohibited entry found Open this evidence | 1 | English and EU languages |
| Great Britain | Source mapped Official source mapped; ingredient rule not imported | 0 | English |
| Canada | Source mapped Official source mapped; ingredient rule not imported | 0 | English and French |
| New Zealand | Source mapped Official source mapped; ingredient rule not imported | 0 | English |
| ASEAN | Source mapped Official source mapped; ingredient rule not imported | 0 | English and national languages |
| China | Source mapped Official source mapped; ingredient rule not imported | 0 | Chinese with selected English material |
| Japan | Source mapped Official source mapped; ingredient rule not imported | 0 | Japanese; official English translation available |
| South Korea | Source mapped Official source mapped; ingredient rule not imported | 0 | Korean with some English names |
| United States | Source mapped Official source mapped; ingredient rule not imported | 0 | English |
| Australia | Source mapped Official source mapped; ingredient rule not imported | 0 | English |
| Brazil | Source mapped Official source mapped; ingredient rule not imported | 0 | Portuguese with INCI crosswalks |
| India | Source mapped Official source mapped; ingredient rule not imported | 0 | English and Hindi |
| Saudi Arabia | Source mapped Official source mapped; ingredient rule not imported | 0 | Arabic and English |
Chemical identity and properties
Dodecamethylcyclohexasiloxane
Dodecamethylcyclohexasiloxane is an organosilicon compound. — ChEBI
- IUPAC name
- 2,2,4,4,6,6,8,8,10,10,12,12-dodecamethyl-1,3,5,7,9,11-hexaoxa-2,4,6,8,10,12-hexasilacyclododecane
- Molecular formula
- C12H36O6Si6
- Molecular weight
- 444.92 g/mol
- Exact mass
- 444.11274807 Da
- Topological polar surface area
- 55.4 Ų
- Hydrogen-bond donors
- 0
- Hydrogen-bond acceptors
- 6
- Covalent units
- 1
- Defined stereocentres
- 0
Also known as
16 more reported names
External database identifiers
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
Decamethylcyclopentasiloxane
Cyclomethicone 5 is member of cyclomethicone, which are a group of liquid methyl siloxanes that have low viscosity and high volatility. Cyclomethicones are cyclic in structure with a monomer backbone of one silicon and two oxygen atoms bonded together. Cyclomethicone 5 is used in cosmetic and personal products as a skin emollient. — DrugBank
- IUPAC name
- 2,2,4,4,6,6,8,8,10,10-decamethyl-1,3,5,7,9,2,4,6,8,10-pentaoxapentasilecane
- Molecular formula
- C10H30O5Si5
- Molecular weight
- 370.77 g/mol
- Exact mass
- 370.09395673 Da
- Topological polar surface area
- 46.2 Ų
- Hydrogen-bond donors
- 0
- Hydrogen-bond acceptors
- 5
- Covalent units
- 1
- Defined stereocentres
- 0
Also known as
16 more reported names
External database identifiers
- ChEBI:CHEBI:191092
- ChEMBL:CHEMBL1885178
- EPA DTXSID:DTXSID1027184
- PubMed:37551828
- PubMed:31836225
- PubMed:27601420
- PubMed:25680588
- PubMed:22966705
- PubMed:22575024
- PubMed:22571757
- PubMed:22304371
- PubMed:22221665
- PubMed:22197313
- PubMed:22097543
- PubMed:21912567
Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
Octamethylcyclotetrasiloxane
Octamethylcyclotetrasiloxane is a cyclosiloxane that is the octamethyl derivative of cyclotetrasiloxane. It is an organosilicon compound and a cyclosiloxane. It derives from a hydride of a cyclotetrasiloxane. — ChEBI
- IUPAC name
- 2,2,4,4,6,6,8,8-octamethyl-1,3,5,7,2,4,6,8-tetraoxatetrasilocane
- Molecular formula
- C8H24O4Si4
- Molecular weight
- 296.61 g/mol
- Exact mass
- 296.07516538 Da
- Topological polar surface area
- 36.9 Ų
- Hydrogen-bond donors
- 0
- Hydrogen-bond acceptors
- 4
- Covalent units
- 1
- Defined stereocentres
- 0
Also known as
16 more reported names
External database identifiers
- ChEBI:CHEBI:25640
- ChEMBL:CHEMBL1869229
- EPA DTXSID:DTXSID7027205
- PubMed:36100151
- PubMed:28927721
- PubMed:27601420
- PubMed:25680588
- PubMed:22594975
- PubMed:22575024
- PubMed:22571757
- PubMed:22304371
- PubMed:22280441
- PubMed:22071495
- PubMed:21901312
- PubMed:21716673
Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
Inventory details for CYCLOMETHICONE
INCI name
CYCLOMETHICONE
INN name
cyclomethicone
Description
Cyclomethicone is a generic name for a mixture of cyclic dimethyl polysiloxane compounds that conform to the formula, where n has a value between 4 and 6.
Record provenance
- Inventory reference
- 33101
- Imported identity
- CYCLOMETHICONE
- Source update
- 30/11/2020
Annex records for CYCLOMETHICONE
Octamethylcyclotetrasiloxane; D4
Key data
- HAIR CONDITIONING
- Enhancing the appearance and feel of hair. Leaving the hair easy to comb, supple, soft and shiny and/or imparting volume, lightness, gloss, texture, etc.
- SKIN CONDITIONING - EMOLLIENT
- Acting as lubricants on the skin surface providing the skin with a soft and smooth appearance.
- SOLVENT
- Dissolving other components of cosmetics. Solvents are usually liquids (aqueous and nonaqueous).
Official EU ingredient-name evidence
The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.
Related inventory evidence
Ingredients with overlapping formulation functions
Additional official and scientific sources
11 external databases to check this identity in
Each link searches that source for this identity. What each source is, and its legal weight
How CYCLOMETHICONE appears in the CosIng inventory
The CosIng inventory lists CYCLOMETHICONE as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.
CYCLOMETHICONE is also tagged with 3 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.
Frequently asked questions
Source note for CYCLOMETHICONE
This page combines the CosIng inventory entry for CYCLOMETHICONE with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.
Use this inventory page to research CYCLOMETHICONE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.
Tools & next steps
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