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InventoryRef 3310430/07/2020

CYCLOTETRASILOXANE

Octamethylcyclotetrasiloxane

CYCLOTETRASILOXANE is linked to 1 EU annex record on this page. Inventory note: II/1388.

Regulatory evidence by market

This matrix separates verified ingredient rules from sources that are mapped but not yet imported. No imported rule does not mean the ingredient is permitted.

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MarketEvidence statusRecordsSource language
European UnionEvidence linked
Prohibited entry found
Open this evidence
1English and EU languages
Great BritainSource mapped
Official source mapped; ingredient rule not imported
0English
CanadaSource mapped
Official source mapped; ingredient rule not imported
0English and French
New ZealandSource mapped
Official source mapped; ingredient rule not imported
0English
ASEANSource mapped
Official source mapped; ingredient rule not imported
0English and national languages
ChinaSource mapped
Official source mapped; ingredient rule not imported
0Chinese with selected English material
JapanSource mapped
Official source mapped; ingredient rule not imported
0Japanese; official English translation available
South KoreaSource mapped
Official source mapped; ingredient rule not imported
0Korean with some English names
United StatesSource mapped
Official source mapped; ingredient rule not imported
0English
AustraliaSource mapped
Official source mapped; ingredient rule not imported
0English
BrazilSource mapped
Official source mapped; ingredient rule not imported
0Portuguese with INCI crosswalks
IndiaSource mapped
Official source mapped; ingredient rule not imported
0English and Hindi
Saudi ArabiaSource mapped
Official source mapped; ingredient rule not imported
0Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 293-51-6
CAS 293-51-6PubChem CID 185471

Cyclotetrasiloxane

Cyclotetrasiloxane is a cyclosiloxane. ChEBI

IUPAC name
1,3,5,7,2,4,6,8-tetraoxatetrasilocane
Molecular formula
H8O4Si4
Molecular weight
184.40 g/mol
Exact mass
183.94996487 Da
Topological polar surface area
36.9 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
4
Covalent units
1
Defined stereocentres
0

Also known as

1,3,5,7,2,4,6,8-tetroxatetrasilocaneCHEBI:481451,3,5,7,2,4,6,8-tetroxatetrasilicocaneRefChem:129999CYCLOTETRASILOXANE [INCI]
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 556-67-2
CAS 556-67-2PubChem CID 11169

Octamethylcyclotetrasiloxane

Octamethylcyclotetrasiloxane is a cyclosiloxane that is the octamethyl derivative of cyclotetrasiloxane. It is an organosilicon compound and a cyclosiloxane. It derives from a hydride of a cyclotetrasiloxane. ChEBI

IUPAC name
2,2,4,4,6,6,8,8-octamethyl-1,3,5,7,2,4,6,8-tetraoxatetrasilocane
Molecular formula
C8H24O4Si4
Molecular weight
296.61 g/mol
Exact mass
296.07516538 Da
Topological polar surface area
36.9 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
4
Covalent units
1
Defined stereocentres
0

Also known as

Cyclotetrasiloxane, octamethyl-OktamethylcyklotetrasiloxanOMCTSCyclic dimethylsiloxane tetramerCyclomethicone 4NUC silicone VS 7207Union carbide 7207Silicone SF 1173
16 more reported names
KF 994SF 1173UC 7207VS 7207NSC-345674CHEBI:25640RefChem:167770209-136-7Simethicone Impurity 3OktamethylzyklotetrasiloxanDimethylsiloxane Cyclic Tetramer2,2,4,4,6,6,8,8-octamethyl-1,3,5,7,2,4,6,8-tetroxatetrasilocaneC8H24O4Si4CAS-556-67-2CCRIS 1327HSDB 6131
External database identifiers

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for CYCLOTETRASILOXANE

INCI name

CYCLOTETRASILOXANE

Description

Octamethylcyclotetrasiloxane

Record provenance

Inventory reference
33104
Imported identity
CYCLOTETRASILOXANE
Source update
30/07/2020
European Commission CosIng source notes

Key data

CAS
556-67-2 / 293-51-6
EC
209-136-7 / -
Restriction
II/1388
Function
HAIR CONDITIONING
Enhancing the appearance and feel of hair. Leaving the hair easy to comb, supple, soft and shiny and/or imparting volume, lightness, gloss, texture, etc.
SKIN CONDITIONING - EMOLLIENT
Acting as lubricants on the skin surface providing the skin with a soft and smooth appearance.
SOLVENT
Dissolving other components of cosmetics. Solvents are usually liquids (aqueous and nonaqueous).

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

Ingredients with overlapping formulation functions

Additional official and scientific sources

11 external databases to check this identity in

How CYCLOTETRASILOXANE appears in the CosIng inventory

The CosIng inventory lists CYCLOTETRASILOXANE as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.

CYCLOTETRASILOXANE is also tagged with 3 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

CYCLOTETRASILOXANE appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

The restriction field for CYCLOTETRASILOXANE reads: "II/1388". This is the restriction note recorded in the CosIng inventory for this ingredient. For authoritative conditions and limits, always refer to the linked annex entries above.

According to the EU CosIng inventory, CYCLOTETRASILOXANE carries the following function designation(s):

CAS 556-67-2 / 293-51-6 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

Source note for CYCLOTETRASILOXANE

This page combines the CosIng inventory entry for CYCLOTETRASILOXANE with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research CYCLOTETRASILOXANE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

Tools & next steps

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