Official EU label nameGlossary entry 7867

CYCLOMETHICONE

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 0 of 13 indexed market datasets: 0 country records and 0 EU Annex records. Every result and evidence gap is listed below.

0 markets with evidence

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Markets with evidence

Evidence gaps

Resolved identifiers

Resolved substance identity

CAS:69430-24-6556-67-2541-02-6540-97-6

EC:209-136-7208-764-9208-762-8

Ingredient index records:

CYCLOMETHICONE

Cosmetic functions: HAIR CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SOLVENT

Cyclomethicone is a generic name for a mixture of cyclic dimethyl polysiloxane compounds that conform to the formula, where n has a value between 4 and 6.

Inventory restriction note: II/1388 (Only when Cyclomethicone contains D4)

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2 matched or reported names

CYCLOMETHICONEcyclomethicone

Regulatory evidence across markets

None of the 13 markets tracked here holds an imported rule under the name CYCLOMETHICONE.

That is a statement about this inventory, not about the law: no imported rule is not evidence that a substance is permitted. A rule may exist under a different name, under a CAS or EC number this glossary entry does not carry, or in a dataset not yet imported.

Check the markets and their sources Search every market for this name

Chemical identity and properties

PubChem 2D chemical structure for CAS 540-97-6

CAS 540-97-6PubChem CID 10911

Dodecamethylcyclohexasiloxane

Dodecamethylcyclohexasiloxane is an organosilicon compound. — ChEBI

IUPAC name: 2,2,4,4,6,6,8,8,10,10,12,12-dodecamethyl-1,3,5,7,9,11-hexaoxa-2,4,6,8,10,12-hexasilacyclododecane

Molecular formula: C12H36O6Si6
Molecular weight: 444.92 g/mol
Exact mass: 444.11274807 Da
Topological polar surface area: 55.4 Å²
Hydrogen-bond donors: 0
Hydrogen-bond acceptors: 6
Covalent units: 1
Defined stereocentres: 0

Also known as

Cyclohexasiloxane, dodecamethyl-Cyclomethicone 6XHK3U310BAXIAMETER PMX-0246RefChem:590100208-762-8CyclohexasiloxaneSimethicone Impurity 5

16 more reported names

2,2,4,4,6,6,8,8,10,10,12,12-DodecamethylcyclohexasiloxaneEINECS 208-762-8UNII-XHK3U310BAC12H36O6Si6HSDB 7723DC 246 fluidDodecamethylhexacyclosiloxaneEC 208-762-8dodecamethyl cyclohexasiloxaneIUMSDRXLFWAGNT-UHFFFAOYSA-CHEBI:191103CYCLOMETHICONE 6 [USP-RS]CYCLOHEXASILOXANE, DODECAMETHYLFS-5671DODECAMETHYLCYCLOHEXASILOXANE [MI]DODECAMETHYLCYCLOHEXASILOXANE [HSDB]

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External database identifiers

ChEBI:CHEBI:191103
EPA DTXSID:DTXSID6027183
PubMed:22575024
PubMed:22304371
PubMed:21901312
PubMed:21723663
PubMed:21662991
PubMed:21072629
PubMed:20954717
PubMed:20926089
PubMed:20836489
PubMed:20704203
PubMed:19361861
PubMed:18443842

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 541-02-6

CAS 541-02-6PubChem CID 10913

Decamethylcyclopentasiloxane

Cyclomethicone 5 is member of cyclomethicone, which are a group of liquid methyl siloxanes that have low viscosity and high volatility. Cyclomethicones are cyclic in structure with a monomer backbone of one silicon and two oxygen atoms bonded together. Cyclomethicone 5 is used in cosmetic and personal products as a skin emollient. — DrugBank

IUPAC name: 2,2,4,4,6,6,8,8,10,10-decamethyl-1,3,5,7,9,2,4,6,8,10-pentaoxapentasilecane

Molecular formula: C10H30O5Si5
Molecular weight: 370.77 g/mol
Exact mass: 370.09395673 Da
Topological polar surface area: 46.2 Å²
Hydrogen-bond donors: 0
Hydrogen-bond acceptors: 5
Covalent units: 1
Defined stereocentres: 0

Also known as

Cyclomethicone 5Dimethylsiloxane pentamerDow corning 345Cyclic dimethylsiloxane pentamerNUC silicone VS 7158Silicon SF 1202CiclopentasiloxaneCyclomethicone D5

16 more reported names

DekamethylcyklopentasiloxanD5-silKF 995VS 71580THT5PCI0RSF 1202Cyclopentasiloxane, 2,2,4,4,6,6,8,8,10,10-decamethyl-JEESILC CPS-211XIAMETER PMX-0245KF-995DOW CORNING ST CYCLOMETHICONE 5Lightening SerumRefChem:54914Smooth and Soft Cuticles3CE PINK IM GOOD MASCARAAuQuest Smooth and Soft Cuticles

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External database identifiers

ChEBI:CHEBI:191092
ChEMBL:CHEMBL1885178
EPA DTXSID:DTXSID1027184
PubMed:37551828
PubMed:31836225
PubMed:27601420
PubMed:25680588
PubMed:22966705
PubMed:22575024
PubMed:22571757
PubMed:22304371
PubMed:22221665
PubMed:22197313
PubMed:22097543
PubMed:21912567

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 556-67-2

CAS 556-67-2PubChem CID 11169

Octamethylcyclotetrasiloxane

Octamethylcyclotetrasiloxane is a cyclosiloxane that is the octamethyl derivative of cyclotetrasiloxane. It is an organosilicon compound and a cyclosiloxane. It derives from a hydride of a cyclotetrasiloxane. — ChEBI

IUPAC name: 2,2,4,4,6,6,8,8-octamethyl-1,3,5,7,2,4,6,8-tetraoxatetrasilocane

Molecular formula: C8H24O4Si4
Molecular weight: 296.61 g/mol
Exact mass: 296.07516538 Da
Topological polar surface area: 36.9 Å²
Hydrogen-bond donors: 0
Hydrogen-bond acceptors: 4
Covalent units: 1
Defined stereocentres: 0

Also known as

Cyclotetrasiloxane, octamethyl-OktamethylcyklotetrasiloxanOMCTSCyclic dimethylsiloxane tetramerCyclomethicone 4NUC silicone VS 7207Union carbide 7207Silicone SF 1173

16 more reported names

KF 994SF 1173UC 7207VS 7207NSC-345674CHEBI:25640RefChem:167770209-136-7Simethicone Impurity 3OktamethylzyklotetrasiloxanDimethylsiloxane Cyclic Tetramer2,2,4,4,6,6,8,8-octamethyl-1,3,5,7,2,4,6,8-tetroxatetrasilocaneC8H24O4Si4CAS-556-67-2CCRIS 1327HSDB 6131

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External database identifiers

ChEBI:CHEBI:25640
ChEMBL:CHEMBL1869229
EPA DTXSID:DTXSID7027205
PubMed:36100151
PubMed:28927721
PubMed:27601420
PubMed:25680588
PubMed:22594975
PubMed:22575024
PubMed:22571757
PubMed:22304371
PubMed:22280441
PubMed:22071495
PubMed:21901312
PubMed:21716673

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Additional authoritative substance research

Each link searches that source for this identity. A link is a research route, not a claim that the source holds an exact record. What each source is, and its legal weight

Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal US EPA CompTox CTX APIs

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Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

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